This article needs attention from an expert in Molecular Biology. The specific problem is: highly technical subject.WikiProject Molecular Biology may be able to help recruit an expert.(January 2019)
The letters TIG stand for TIS granules and letters ER stands for the endoplasmic reticulum. TIS granules form a network of interconnected proteins that bind RNA and the endoplasmic reticulum is where protein synthesis occurs. This combination of the TIS proteins and the endoplasmic reticulum creates a distinct place in which mRNA and proteins collect, interact, and grow. The striped pattern of the TIS granules that are interweaving with the endoplasmic reticulum also resemble the orange and black stripes of a tiger. The TIGER domain has been found in all types of cells scientists have looked at so far.[1][2][3][4][5][6]
Referencesedit
^ abMa, Weiru; Mayr, Christine (November 15, 2018). "A Membraneless Organelle Associated with the Endoplasmic Reticulum Enables 3′UTR-Mediated Protein-Protein Interactions". Cell. 175 (6). Cell Press: 1492–1506.e19. doi:10.1016/j.cell.2018.10.007. PMC6711188. PMID 30449617.
^ ab"A Membraneless Organelle Associated with the Endoplasmic Reticulum Enables 3′UTR-Mediated Protein-Protein Interactions". ScienceDirect. November 15, 2018. Retrieved November 21, 2018.
tiger, domain, this, article, needs, attention, from, expert, molecular, biology, specific, problem, highly, technical, subject, wikiproject, molecular, biology, able, help, recruit, expert, january, 2019, minor, membraneless, organelle, which, messenger, mrna. This article needs attention from an expert in Molecular Biology The specific problem is highly technical subject WikiProject Molecular Biology may be able to help recruit an expert January 2019 The TIGER domain is a minor membraneless organelle in which messenger RNA mRNA encodes certain types of proteins to find the appropriate environment for growth It is closely associated with the endoplasmic reticulum during protein synthesis The TIGER domain was first documented by cell biologists Christine Mayr and Weirui Ma at the Gerstner Sloan Kettering Graduate School of Biomedical Sciences in 2018 1 2 3 4 5 6 The letters TIG stand for TIS granules and letters ER stands for the endoplasmic reticulum TIS granules form a network of interconnected proteins that bind RNA and the endoplasmic reticulum is where protein synthesis occurs This combination of the TIS proteins and the endoplasmic reticulum creates a distinct place in which mRNA and proteins collect interact and grow The striped pattern of the TIS granules that are interweaving with the endoplasmic reticulum also resemble the orange and black stripes of a tiger The TIGER domain has been found in all types of cells scientists have looked at so far 1 2 3 4 5 6 References edit a b Ma Weiru Mayr Christine November 15 2018 A Membraneless Organelle Associated with the Endoplasmic Reticulum Enables 3 UTR Mediated Protein Protein Interactions Cell 175 6 Cell Press 1492 1506 e19 doi 10 1016 j cell 2018 10 007 PMC 6711188 PMID 30449617 a b A Membraneless Organelle Associated with the Endoplasmic Reticulum Enables 3 UTR Mediated Protein Protein Interactions ScienceDirect November 15 2018 Retrieved November 21 2018 a b Otto Grant November 27 2018 Protein trafficking through TIGER domains Nature Reviews Molecular Cell Biology 20 1 3 doi 10 1038 s41580 018 0088 9 PMID 30479375 a b Tontonoz Matthew November 15 2018 This Newly Discovered Organelle Is Fierce Memorial Sloan Kettering Cancer Center Retrieved November 21 2018 a b The Christine Mayr Lab Gerstner Sloan Kettering Graduate School of Biomedical Sciences Retrieved November 21 2018 a b Christine Mayr Overview Gerstner Sloan Kettering Graduate School of Biomedical Sciences Retrieved November 21 2018 oi popk u nbsp This cell biology article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title TIGER domain amp oldid 1022571531, wikipedia, wiki, book, books, library,
