D'Este was the son of Prince Augustus Frederick, Duke of Sussex, and Lady Augusta Murray, and a grandson of King George III. His parents were secretly married on 4 April 1793, in a Church of England ceremony in Rome at the Hotel Sarmiento, and later married again on 5 December 1793 at St George's, Hanover Square, Westminster, using their correct names but without revealing their identities. Both marriages were in defiance of the Royal Marriages Act 1772 and were thus legally null and void, at least in English law. After the birth of their first child, the marriage was discovered by the King and formally annulled, making their son illegitimate in Great Britain. Christened "Augustus Frederick", he was briefly given the surname of "Hanover", but later took the name of d'Este. He attended Harrow School.
He was commissioned into the Army as a lieutenant in the 7th Regiment of Foot in 1811.[1] He was promoted to be captain of a company in the York Chasseurs in 1815,[2] shortly afterwards transferring to the 12th Regiment of Foot,[3] and then to the captaincy of a troop in the 9th Regiment of Light Dragoons in 1817.[4] In 1822 he purchased the rank of major in the 11th Regiment of Foot,[5] exchanging into the 4th Regiment of Dragoon Guards later that year.[6] He was promoted by purchase to lieutenant-colonel on the unattached list in 1824,[7] and granted the brevet rank of colonel in 1838.[8] In 1830 the new king William IV appointed him a knight commander in the civil division of the Hanoverian Guelphic Order[9] and a British knight bachelor.[10] He was also granted a civil list pension and made deputy ranger of St James's Park and Hyde Park.[11]
An active member of the Aborigines Protection Society particularly interested in Native Americans, d'Este gave considerable assistance to Peter Jones, the Mississauga missionary and leader, who argued for Native Americans to have title to their lands in Upper Canada.[11]
When his father died in 1843, Sir Augustus d'Este attempted to claim his dukedom of Sussex and other peerages, but the House of Lords decided against his claim, as the prince's marriage had been null and void.[11] Although he had affairs with women, he never married[12] and, therefore, even if he had succeeded to his father's titles, they would have become extinct on his own death.
Illnessedit
Augustus d'Este is the earliest recorded person for whom a definite diagnosis of multiple sclerosis can be made.[13][14][15] The course of his MS, which was not diagnosed during his lifetime, is known from the diaries he kept. D'Este left a detailed diary describing his 22 years living with the disease. He began his diary in 1822 and it had its last entry in 1846; only to remain unknown until 1948.[16] His symptoms began at age 28, with a sudden transient visual loss after the funeral of a friend. During the course of his disease he developed weakness of the legs, clumsiness of the hands, numbness, dizziness, bladder disturbances, and erectile dysfunction. By 1843 he was experiencing persistent symptoms including tremor and nocturnal spasms, and in 1844 he began to use a wheelchair. In his last years he was confined to his bed. Despite his illness, he kept an optimistic view of life.[11]
^Landtblom, Anne-Marie; Fazio Patrik; Fredrikson Sten; Granieri Enrico (February 2010). "The first case history of multiple sclerosis: Augustus d'Este (1794–1848)". Neurol. Sci. 31 (1): 29–33. doi:10.1007/s10072-009-0161-4. PMID 19838623. S2CID 12209261.
^Landtblom, Anne-Marie; Granieri, Enrico; Fredrikson, Sten (2007). "Augustus d'Este — the first documented case of MS". Läkartidningen (in Swedish). 104 (26–27): 2009–11. ISSN 0023-7205. PMID 17639800.
^Firth, D (1948). The Case of August d'Esté. Cambridge: Cambridge University Press.
April 18, 2024
augustus, este, augustus, frederick, este, january, 1794, december, 1848, relative, british, royal, family, earliest, recorded, person, whom, definite, diagnosis, multiple, sclerosis, made, only, prince, augustus, frederick, duke, sussex, wife, lady, augusta, . Sir Augustus Frederick d Este KCH 13 January 1794 28 December 1848 was a relative of the British royal family and the earliest recorded person for whom a definite diagnosis of multiple sclerosis can be made He was the only son of Prince Augustus Frederick Duke of Sussex and his wife Lady Augusta Murray He was a grandson of George III nephew of George IV and William IV and a first cousin to Victoria Queen of the United Kingdom SirAugustus d EsteKCHBornAugustus Frederick Hanover 1794 01 13 13 January 1794London Great BritainDied28 December 1848 1848 12 28 aged 54 Ramsgate KentParent s Prince Augustus Frederick Duke of SussexLady Augusta Murray Contents 1 Family and career 2 Illness 3 Ancestry 4 ReferencesFamily and career editD Este was the son of Prince Augustus Frederick Duke of Sussex and Lady Augusta Murray and a grandson of King George III His parents were secretly married on 4 April 1793 in a Church of England ceremony in Rome at the Hotel Sarmiento and later married again on 5 December 1793 at St George s Hanover Square Westminster using their correct names but without revealing their identities Both marriages were in defiance of the Royal Marriages Act 1772 and were thus legally null and void at least in English law After the birth of their first child the marriage was discovered by the King and formally annulled making their son illegitimate in Great Britain Christened Augustus Frederick he was briefly given the surname of Hanover but later took the name of d Este He attended Harrow School He was commissioned into the Army as a lieutenant in the 7th Regiment of Foot in 1811 1 He was promoted to be captain of a company in the York Chasseurs in 1815 2 shortly afterwards transferring to the 12th Regiment of Foot 3 and then to the captaincy of a troop in the 9th Regiment of Light Dragoons in 1817 4 In 1822 he purchased the rank of major in the 11th Regiment of Foot 5 exchanging into the 4th Regiment of Dragoon Guards later that year 6 He was promoted by purchase to lieutenant colonel on the unattached list in 1824 7 and granted the brevet rank of colonel in 1838 8 In 1830 the new king William IV appointed him a knight commander in the civil division of the Hanoverian Guelphic Order 9 and a British knight bachelor 10 He was also granted a civil list pension and made deputy ranger of St James s Park and Hyde Park 11 An active member of the Aborigines Protection Society particularly interested in Native Americans d Este gave considerable assistance to Peter Jones the Mississauga missionary and leader who argued for Native Americans to have title to their lands in Upper Canada 11 When his father died in 1843 Sir Augustus d Este attempted to claim his dukedom of Sussex and other peerages but the House of Lords decided against his claim as the prince s marriage had been null and void 11 Although he had affairs with women he never married 12 and therefore even if he had succeeded to his father s titles they would have become extinct on his own death Illness editAugustus d Este is the earliest recorded person for whom a definite diagnosis of multiple sclerosis can be made 13 14 15 The course of his MS which was not diagnosed during his lifetime is known from the diaries he kept D Este left a detailed diary describing his 22 years living with the disease He began his diary in 1822 and it had its last entry in 1846 only to remain unknown until 1948 16 His symptoms began at age 28 with a sudden transient visual loss after the funeral of a friend During the course of his disease he developed weakness of the legs clumsiness of the hands numbness dizziness bladder disturbances and erectile dysfunction By 1843 he was experiencing persistent symptoms including tremor and nocturnal spasms and in 1844 he began to use a wheelchair In his last years he was confined to his bed Despite his illness he kept an optimistic view of life 11 Ancestry editAncestors of Augustus d Este8 Frederick Prince of Wales4 George III of the United Kingdom9 Princess Augusta of Saxe Gotha2 Prince Augustus Frederick Duke of Sussex10 Duke Charles Louis Frederick of Mecklenburg Strelitz5 Duchess Charlotte of Mecklenburg Strelitz11 Princess Elisabeth Albertine of Saxe Hildburghausen1 Augustus d Este12 William Murray 3rd Earl of Dunmore6 John Murray 4th Earl of Dunmore13 The Honourable Catherine Murray3 Lady Augusta Murray14 Alexander Stewart 6th Earl of Galloway7 Lady Charlotte Stewart15 Lady Catherine CochraneReferences edit No 16526 The London Gazette 28 September 1 October 1811 p 1914 No 16998 The London Gazette 28 March 1815 p 586 No 17040 The London Gazette 15 July 1815 p 1426 No 17248 The London Gazette 6 May 1817 p 1087 No 17836 The London Gazette 20 July 1822 p 1194 No 17872 The London Gazette 23 November 1822 p 1915 No 18043 The London Gazette 10 July 1824 p 1132 No 19631 The London Gazette 3 July 1838 p 1489 William A Shaw The Knights of England London 1906 vol I p 456 William A Shaw The Knights of England London 1906 vol II p 329 a b c d Reynolds K D 2004 d Este Sir Augustus Frederick 1794 1848 Oxford Dictionary of National Biography Oxford University Press Kenny James 18 September 2015 My case Sir Augustus Frederick d Este Royal College of Physicians website Retrieved 16 May 2018 Compston Alastair et al 2005 McAlpine s Multiple Sclerosis 4th ed Churchill Livingstone Landtblom Anne Marie Fazio Patrik Fredrikson Sten Granieri Enrico February 2010 The first case history of multiple sclerosis Augustus d Este 1794 1848 Neurol Sci 31 1 29 33 doi 10 1007 s10072 009 0161 4 PMID 19838623 S2CID 12209261 Landtblom Anne Marie Granieri Enrico Fredrikson Sten 2007 Augustus d Este the first documented case of MS Lakartidningen in Swedish 104 26 27 2009 11 ISSN 0023 7205 PMID 17639800 Firth D 1948 The Case of August d Este Cambridge Cambridge University Press Retrieved from https en wikipedia org w index php title Augustus d 27Este amp oldid 1204036593, wikipedia, wiki, book, books, library,
