Wikipedia
Scutelarin
Scutelarin (EC 3.4.21.60, taipan activator, Oxyuranus scutellatus prothrombin-activating proteinase) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction
| Scutelarin | |
|---|---|
| Identifiers | |
| EC no. | 3.4.21.60 |
| CAS no. | 93389-45-8 |
| Databases | |
| IntEnz | IntEnz view |
| BRENDA | BRENDA entry |
| ExPASy | NiceZyme view |
| KEGG | KEGG entry |
| MetaCyc | metabolic pathway |
| PRIAM | profile |
| PDB structures | RCSB PDB PDBe PDBsum |
- Selective cleavage of Arg-Thr and Arg-Ile in prothrombin to form thrombin and two inactive fragments
This enzyme is isolated from the venom of the Taipan snake (Oxyuranus scutellatus).
References edit
- ^ Walker FJ, Owen WG, Esmon CT (March 1980). "Characterization of the prothrombin activator from the venom of Oxyuranus scutellatus scutellatus (taipan venom)". Biochemistry. 19 (5): 1020–3. doi:10.1021/bi00546a029. PMID 6986908.
- ^ Speijer H, Govers-Riemslag JW, Zwaal RF, Rosing J (October 1986). "Prothrombin activation by an activator from the venom of Oxyuranus scutellatus (Taipan snake)". The Journal of Biological Chemistry. 261 (28): 13258–67. PMID 3531198.
External links edit
- Scutelarin at the U.S. National Library of Medicine Medical Subject Headings (MeSH)