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Wikipedia

SPRR2A

January 01, 1970

Small proline-rich protein 2A is a protein that in humans is encoded by the SPRR2A gene.[5][6]

SPRR2A
Identifiers
AliasesSPRR2A, small proline rich protein 2A
External IDsOMIM: 182267 MGI: 1330343 HomoloGene: 130544 GeneCards: SPRR2A
Orthologs
SpeciesHumanMouse
Entrez

6700

20762

Ensembl

ENSG00000241794

ENSMUSG00000046259

UniProt

P35326

O70559

RefSeq (mRNA)

NM_005988

NM_011474

RefSeq (protein)

NP_005979

NP_035604

Location (UCSC)Chr 1: 153.06 – 153.06 MbChr 3: 92.29 – 92.29 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References edit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000241794 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000046259 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Gibbs S, Fijneman R, Wiegant J, van Kessel AG, van De Putte P, Backendorf C (Aug 1993). "Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins". Genomics. 16 (3): 630–7. doi:10.1006/geno.1993.1240. PMID 8325635.
  6. ^ "Entrez Gene: SPRR2A small proline-rich protein 2A".

Further reading edit

  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
  • Tong L, Corrales RM, Chen Z, et al. (2006). "Expression and Regulation of Cornified Envelope Proteins in Human Corneal Epithelium". Invest. Ophthalmol. Vis. Sci. 47 (5): 1938–46. doi:10.1167/iovs.05-1129. PMC 2906387. PMID 16639001.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Hong SH, Nah HY, Lee JY, et al. (2004). "Estrogen regulates the expression of the small proline-rich 2 gene family in the mouse uterus". Mol. Cells. 17 (3): 477–84. doi:10.1016/S1016-8478(23)13069-X. PMID 15232223.
  • Cabral A, Fischer DF, Vermeij WP, Backendorf C (2003). "Distinct functional interactions of human Skn-1 isoforms with Ese-1 during keratinocyte terminal differentiation". J. Biol. Chem. 278 (20): 17792–9. doi:10.1074/jbc.M300508200. hdl:1887/50054. PMID 12624109.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. Bibcode:2000PNAS...97.3491D. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800.
  • Fischer DF, van Drunen CM, Winkler GS, et al. (1999). "Involvement of a nuclear matrix association region in the regulation of the SPRR2A keratinocyte terminal differentiation marker". Nucleic Acids Res. 26 (23): 5288–94. doi:10.1093/nar/26.23.5288. PMC 147987. PMID 9826750.
  • Steinert PM, Marekov LN (1997). "Direct evidence that involucrin is a major early isopeptide cross-linked component of the keratinocyte cornified cell envelope". J. Biol. Chem. 272 (3): 2021–30. doi:10.1074/jbc.272.3.2021. PMID 8999895.
  • Fischer DF, Gibbs S, van De Putte P, Backendorf C (1996). "Interdependent transcription control elements regulate the expression of the SPRR2A gene during keratinocyte terminal differentiation". Mol. Cell. Biol. 16 (10): 5365–74. doi:10.1128/MCB.16.10.5365. PMC 231535. PMID 8816448.
  • Gibbs S, Lohman F, Teubel W, et al. (1990). "Characterization of the human spr2 promoter: induction after UV irradiation or TPA treatment and regulation during differentiation of cultured primary keratinocytes". Nucleic Acids Res. 18 (15): 4401–7. doi:10.1093/nar/18.15.4401. PMC 331257. PMID 2388825.


 

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it.

January 01, 1970
sprr2a, small, proline, rich, protein, protein, that, humans, encoded, gene, identifiersaliases, small, proline, rich, protein, 2aexternal, idsomim, 182267, 1330343, homologene, 130544, genecards, gene, location, human, chromosome, human, band1q21, 3start153, . Small proline rich protein 2A is a protein that in humans is encoded by the SPRR2A gene 5 6 SPRR2AIdentifiersAliasesSPRR2A small proline rich protein 2AExternal IDsOMIM 182267 MGI 1330343 HomoloGene 130544 GeneCards SPRR2AGene location Human Chr Chromosome 1 human 1 Band1q21 3Start153 056 120 bp 1 End153 057 512 bp 1 Gene location Mouse Chr Chromosome 3 mouse 2 Band3 F1 3 40 14 cMStart92 292 992 bp 2 End92 294 631 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed ingumsbody of tongueamniotic fluidoral cavityhuman penisvulvasuperior surface of tonguepalpebral conjunctivaspermvaginaTop expressed incervixskin of backlipskin of abdomenbelly cordsexually immature organismesophagushair follicleforegutlimbMore reference expression dataBioGPSMore reference expression dataGene ontologyMolecular functionprotein binding structural molecule activityCellular componentcytoplasm cornified envelope cytosolBiological processpeptide cross linking keratinization keratinocyte differentiation epidermis development cornificationSources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez670020762EnsemblENSG00000241794ENSMUSG00000046259UniProtP35326O70559RefSeq mRNA NM 005988NM 011474RefSeq protein NP 005979NP 035604Location UCSC Chr 1 153 06 153 06 MbChr 3 92 29 92 29 MbPubMed search 3 4 WikidataView Edit HumanView Edit MouseReferences edit a b c GRCh38 Ensembl release 89 ENSG00000241794 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000046259 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Gibbs S Fijneman R Wiegant J van Kessel AG van De Putte P Backendorf C Aug 1993 Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline rich proteins Genomics 16 3 630 7 doi 10 1006 geno 1993 1240 PMID 8325635 Entrez Gene SPRR2A small proline rich protein 2A Further reading editGregory SG Barlow KF McLay KE et al 2006 The DNA sequence and biological annotation of human chromosome 1 Nature 441 7091 315 21 Bibcode 2006Natur 441 315G doi 10 1038 nature04727 PMID 16710414 Tong L Corrales RM Chen Z et al 2006 Expression and Regulation of Cornified Envelope Proteins in Human Corneal Epithelium Invest Ophthalmol Vis Sci 47 5 1938 46 doi 10 1167 iovs 05 1129 PMC 2906387 PMID 16639001 Gerhard DS Wagner L Feingold EA et al 2004 The Status Quality and Expansion of the NIH Full Length cDNA Project The Mammalian Gene Collection MGC Genome Res 14 10B 2121 7 doi 10 1101 gr 2596504 PMC 528928 PMID 15489334 Hong SH Nah HY Lee JY et al 2004 Estrogen regulates the expression of the small proline rich 2 gene family in the mouse uterus Mol Cells 17 3 477 84 doi 10 1016 S1016 8478 23 13069 X PMID 15232223 Cabral A Fischer DF Vermeij WP Backendorf C 2003 Distinct functional interactions of human Skn 1 isoforms with Ese 1 during keratinocyte terminal differentiation J Biol Chem 278 20 17792 9 doi 10 1074 jbc M300508200 hdl 1887 50054 PMID 12624109 Strausberg RL Feingold EA Grouse LH et al 2003 Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 99 26 16899 903 Bibcode 2002PNAS 9916899M doi 10 1073 pnas 242603899 PMC 139241 PMID 12477932 Dias Neto E Correa RG Verjovski Almeida S et al 2000 Shotgun sequencing of the human transcriptome with ORF expressed sequence tags Proc Natl Acad Sci U S A 97 7 3491 6 Bibcode 2000PNAS 97 3491D doi 10 1073 pnas 97 7 3491 PMC 16267 PMID 10737800 Fischer DF van Drunen CM Winkler GS et al 1999 Involvement of a nuclear matrix association region in the regulation of the SPRR2A keratinocyte terminal differentiation marker Nucleic Acids Res 26 23 5288 94 doi 10 1093 nar 26 23 5288 PMC 147987 PMID 9826750 Steinert PM Marekov LN 1997 Direct evidence that involucrin is a major early isopeptide cross linked component of the keratinocyte cornified cell envelope J Biol Chem 272 3 2021 30 doi 10 1074 jbc 272 3 2021 PMID 8999895 Fischer DF Gibbs S van De Putte P Backendorf C 1996 Interdependent transcription control elements regulate the expression of the SPRR2A gene during keratinocyte terminal differentiation Mol Cell Biol 16 10 5365 74 doi 10 1128 MCB 16 10 5365 PMC 231535 PMID 8816448 Gibbs S Lohman F Teubel W et al 1990 Characterization of the human spr2 promoter induction after UV irradiation or TPA treatment and regulation during differentiation of cultured primary keratinocytes Nucleic Acids Res 18 15 4401 7 doi 10 1093 nar 18 15 4401 PMC 331257 PMID 2388825 nbsp This article on a gene on human chromosome 1 is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title SPRR2A amp oldid 1193893575, wikipedia, wiki, book, books, library,

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