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Wikipedia

SPIN1

August 28, 2023

Spindlin-1 is a protein that in humans is encoded by the SPIN1 gene.[5][6]

SPIN1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSPIN1, SPIN, TDRD24, spindlin 1
External IDsOMIM: 609936 MGI: 109242 HomoloGene: 55983 GeneCards: SPIN1
Orthologs
SpeciesHumanMouse
Entrez

10927

20729

Ensembl

ENSG00000106723

ENSMUSG00000021395

UniProt

Q9Y657

Q61142

RefSeq (mRNA)

NM_006717

NM_001283028
NM_001283029
NM_001283030
NM_011462
NM_146043

RefSeq (protein)

NP_006708

NP_001269957
NP_001269958
NP_001269959
NP_035592
NP_666155

Location (UCSC)Chr 9: 88.39 – 88.48 MbChr 13: 51.25 – 51.31 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


References Edit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000106723 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021395 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Gao Y, Yue W, Zhang P, Li L, Xie X, Yuan H, Chen L, Liu D, Yan F, Pei X (Aug 2005). "Spindlin1, a novel nuclear protein with a role in the transformation of NIH3T3 cells". Biochem Biophys Res Commun. 335 (2): 343–50. doi:10.1016/j.bbrc.2005.07.087. PMID 16098913. S2CID 44944387.
  6. ^ "Entrez Gene: SPIN1 spindlin 1".

Further reading Edit

  • Oh B, Hwang SY, Solter D, Knowles BB (1997). "Spindlin, a major maternal transcript expressed in the mouse during the transition from oocyte to embryo". Development. 124 (2): 493–503. doi:10.1242/dev.124.2.493. PMID 9053325.
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. Bibcode:2004Natur.429..369H. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
  • Jiang F, Zhao Q, Qin L, et al. (2006). "Expression, purification, crystallization and preliminary X-ray analysis of human spindlin1, an ovarian cancer-related protein". Protein Pept. Lett. 13 (2): 203–5. doi:10.2174/092986606775101661. PMID 16472086.
  • Zhao Q, Qin L, Jiang F, et al. (2007). "Structure of human spindlin1. Tandem tudor-like domains for cell cycle regulation". J. Biol. Chem. 282 (1): 647–56. doi:10.1074/jbc.M604029200. PMID 17082182.


 

This article on a gene on human chromosome 9 is a stub. You can help Wikipedia by expanding it.

August 28, 2023
spin1, spindlin, protein, that, humans, encoded, gene, available, structurespdbortholog, search, pdbe, rcsblist, codes2ns2, 4h75, 4mzf, 4mzg, 4mzhidentifiersaliases, spin, tdrd24, spindlin, 1external, idsomim, 609936, 109242, homologene, 55983, genecards, gene. Spindlin 1 is a protein that in humans is encoded by the SPIN1 gene 5 6 SPIN1Available structuresPDBOrtholog search PDBe RCSBList of PDB id codes2NS2 4H75 4MZF 4MZG 4MZHIdentifiersAliasesSPIN1 SPIN TDRD24 spindlin 1External IDsOMIM 609936 MGI 109242 HomoloGene 55983 GeneCards SPIN1Gene location Human Chr Chromosome 9 human 1 Band9q22 1Start88 388 430 bp 1 End88 478 694 bp 1 Gene location Mouse Chr Chromosome 13 mouse 2 Band13 A5 13 26 04 cMStart51 254 916 bp 2 End51 306 582 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed inpostcentral gyruscaput epididymiscorpus epididymissuperior vestibular nucleusmiddle temporal gyrusentorhinal cortexBrodmann area 23seminal vesicularenal medullasuperior frontal gyrusTop expressed insecondary oocytefossacondylemotor neuronPaneth cellsubstantia nigrafacial motor nucleusmedial ganglionic eminencevas deferensbarrel cortexMore reference expression dataBioGPSMore reference expression dataGene ontologyMolecular functionmethylated histone binding protein bindingCellular componentnucleus spindle nucleolus nucleoplasm cytosol nuclear membraneBiological processmulticellular organism development Wnt signaling pathway cell cycle meiosis rRNA transcription gamete generation positive regulation of Wnt signaling pathway positive regulation of transcription DNA templated chromatin organizationSources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez1092720729EnsemblENSG00000106723ENSMUSG00000021395UniProtQ9Y657Q61142RefSeq mRNA NM 006717NM 001283028NM 001283029NM 001283030NM 011462NM 146043RefSeq protein NP 006708NP 001269957NP 001269958NP 001269959NP 035592NP 666155Location UCSC Chr 9 88 39 88 48 MbChr 13 51 25 51 31 MbPubMed search 3 4 WikidataView Edit HumanView Edit MouseReferences Edit a b c GRCh38 Ensembl release 89 ENSG00000106723 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000021395 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Gao Y Yue W Zhang P Li L Xie X Yuan H Chen L Liu D Yan F Pei X Aug 2005 Spindlin1 a novel nuclear protein with a role in the transformation of NIH3T3 cells Biochem Biophys Res Commun 335 2 343 50 doi 10 1016 j bbrc 2005 07 087 PMID 16098913 S2CID 44944387 Entrez Gene SPIN1 spindlin 1 Further reading EditOh B Hwang SY Solter D Knowles BB 1997 Spindlin a major maternal transcript expressed in the mouse during the transition from oocyte to embryo Development 124 2 493 503 doi 10 1242 dev 124 2 493 PMID 9053325 Hartley JL Temple GF Brasch MA 2001 DNA cloning using in vitro site specific recombination Genome Res 10 11 1788 95 doi 10 1101 gr 143000 PMC 310948 PMID 11076863 Wiemann S Weil B Wellenreuther R et al 2001 Toward a catalog of human genes and proteins sequencing and analysis of 500 novel complete protein coding human cDNAs Genome Res 11 3 422 35 doi 10 1101 gr GR1547R PMC 311072 PMID 11230166 Simpson JC Wellenreuther R Poustka A et al 2001 Systematic subcellular localization of novel proteins identified by large scale cDNA sequencing EMBO Rep 1 3 287 92 doi 10 1093 embo reports kvd058 PMC 1083732 PMID 11256614 Strausberg RL Feingold EA Grouse LH et al 2003 Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 99 26 16899 903 Bibcode 2002PNAS 9916899M doi 10 1073 pnas 242603899 PMC 139241 PMID 12477932 Ota T Suzuki Y Nishikawa T et al 2004 Complete sequencing and characterization of 21 243 full length human cDNAs Nat Genet 36 1 40 5 doi 10 1038 ng1285 PMID 14702039 Humphray SJ Oliver K Hunt AR et al 2004 DNA sequence and analysis of human chromosome 9 Nature 429 6990 369 74 Bibcode 2004Natur 429 369H doi 10 1038 nature02465 PMC 2734081 PMID 15164053 Gerhard DS Wagner L Feingold EA et al 2004 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 10B 2121 7 doi 10 1101 gr 2596504 PMC 528928 PMID 15489334 Wiemann S Arlt D Huber W et al 2004 From ORFeome to biology a functional genomics pipeline Genome Res 14 10B 2136 44 doi 10 1101 gr 2576704 PMC 528930 PMID 15489336 Mehrle A Rosenfelder H Schupp I et al 2006 The LIFEdb database in 2006 Nucleic Acids Res 34 Database issue D415 8 doi 10 1093 nar gkj139 PMC 1347501 PMID 16381901 Jiang F Zhao Q Qin L et al 2006 Expression purification crystallization and preliminary X ray analysis of human spindlin1 an ovarian cancer related protein Protein Pept Lett 13 2 203 5 doi 10 2174 092986606775101661 PMID 16472086 Zhao Q Qin L Jiang F et al 2007 Structure of human spindlin1 Tandem tudor like domains for cell cycle regulation J Biol Chem 282 1 647 56 doi 10 1074 jbc M604029200 PMID 17082182 This article on a gene on human chromosome 9 is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title SPIN1 amp oldid 1171082315, wikipedia, 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