^ abcGRCh38: Ensembl release 89: ENSG00000165349 - Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000031297 - Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Vekony N, Wolf S, Boissel JP, Gnauert K, Closs EI (Oct 2001). "Human cationic amino acid transporter hCAT-3 is preferentially expressed in peripheral tissues". Biochemistry. 40 (41): 12387–94. doi:10.1021/bi011345c. PMID 11591158.
^ ab"Entrez Gene: SLC7A3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3".
Further readingEdit
Hosokawa H, Sawamura T, Kobayashi S, et al. (1997). "Cloning and characterization of a brain-specific cationic amino acid transporter". J. Biol. Chem. 272 (13): 8717–22. doi:10.1074/jbc.272.13.8717. PMID 9079705.
Ito K, Groudine M (1997). "A new member of the cationic amino acid transporter family is preferentially expressed in adult mouse brain". J. Biol. Chem. 272 (42): 26780–6. doi:10.1074/jbc.272.42.26780. PMID 9334265.
Hosokawa H, Ninomiya H, Sawamura T, et al. (1999). "Neuron-specific expression of cationic amino acid transporter 3 in the adult rat brain". Brain Res. 838 (1–2): 158–65. doi:10.1016/S0006-8993(99)01686-8. PMID 10446328. S2CID 33405664.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC528928. PMID 15489334.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
Rotmann A, Vékony N, Gassner D, et al. (2006). "Activation of classical protein kinase C reduces the expression of human cationic amino acid transporter 3 (hCAT-3) in the plasma membrane". Biochem. J. 395 (1): 117–23. doi:10.1042/BJ20051558. PMC1409692. PMID 16332251.
cationic, amino, acid, transporter, protein, that, humans, encoded, slc7a3, gene, slc7a3identifiersaliasesslc7a3, atrc3, cat3, solute, carrier, family, member, 3external, idsomim, 300443, 1100521, homologene, 56382, genecards, slc7a3gene, location, human, chro. Cationic amino acid transporter 3 is a protein that in humans is encoded by the SLC7A3 gene 5 6 SLC7A3IdentifiersAliasesSLC7A3 ATRC3 CAT 3 CAT3 solute carrier family 7 member 3External IDsOMIM 300443 MGI 1100521 HomoloGene 56382 GeneCards SLC7A3Gene location Human Chr X chromosome human 1 BandXq13 1Start70 925 579 bp 1 End70 931 125 bp 1 Gene location Mouse Chr X chromosome mouse 2 BandX X C3 DStart100 122 816 bp 2 End100 129 626 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed intibialis anterior musclethymusganglionic eminencegastric mucosadeltoid musclehypothalamusspermsmooth muscle tissuecorpus epididymiscaput epididymisTop expressed indorsomedial hypothalamic nucleusotic placodeventral tegmental areaparaventricular nucleus of hypothalamuslateral hypothalamusprimitive streakventromedial nucleussubstantia nigrasubiculumarcuate nucleusMore reference expression dataBioGPSn aGene ontologyMolecular functionbasic amino acid transmembrane transporter activity L lysine transmembrane transporter activity amino acid transmembrane transporter activity transmembrane transporter activity L ornithine transmembrane transporter activityCellular componentintegral component of membrane membrane plasma membraneBiological processbasic amino acid transmembrane transport L lysine transmembrane transport L alpha amino acid transmembrane transport L arginine transmembrane transport amino acid transport transmembrane transport L arginine import across plasma membrane L ornithine transmembrane transportSources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez8488911989EnsemblENSG00000165349ENSMUSG00000031297UniProtQ8WY07P70423RefSeq mRNA NM 032803NM 001048164NM 001301840NM 007515RefSeq protein NP 001041629NP 116192NP 001288769NP 031541Location UCSC Chr X 70 93 70 93 MbChr X 100 12 100 13 MbPubMed search 3 4 WikidataView Edit HumanView Edit MouseSLC7A3 is a member of the system y family of transporters characterized by sodium independent transport of cationic amino acids supplied by OMIM 6 See also EditSolute carrier familyReferences Edit a b c GRCh38 Ensembl release 89 ENSG00000165349 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000031297 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Vekony N Wolf S Boissel JP Gnauert K Closs EI Oct 2001 Human cationic amino acid transporter hCAT 3 is preferentially expressed in peripheral tissues Biochemistry 40 41 12387 94 doi 10 1021 bi011345c PMID 11591158 a b Entrez Gene SLC7A3 solute carrier family 7 cationic amino acid transporter y system member 3 Further reading EditHosokawa H Sawamura T Kobayashi S et al 1997 Cloning and characterization of a brain specific cationic amino acid transporter J Biol Chem 272 13 8717 22 doi 10 1074 jbc 272 13 8717 PMID 9079705 Ito K Groudine M 1997 A new member of the cationic amino acid transporter family is preferentially expressed in adult mouse brain J Biol Chem 272 42 26780 6 doi 10 1074 jbc 272 42 26780 PMID 9334265 Hosokawa H Ninomiya H Sawamura T et al 1999 Neuron specific expression of cationic amino acid transporter 3 in the adult rat brain Brain Res 838 1 2 158 65 doi 10 1016 S0006 8993 99 01686 8 PMID 10446328 S2CID 33405664 Strausberg RL Feingold EA Grouse LH et al 2003 Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 99 26 16899 903 Bibcode 2002PNAS 9916899M doi 10 1073 pnas 242603899 PMC 139241 PMID 12477932 Ota T Suzuki Y Nishikawa T et al 2004 Complete sequencing and characterization of 21 243 full length human cDNAs Nat Genet 36 1 40 5 doi 10 1038 ng1285 PMID 14702039 Gerhard DS Wagner L Feingold EA et al 2004 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 10B 2121 7 doi 10 1101 gr 2596504 PMC 528928 PMID 15489334 Gilles W Vulcu SD Liewald JF et al 2005 Monovalent cation conductance in Xenopus laevis oocytes expressing hCAT 3 Biochim Biophys Acta 1668 2 234 9 doi 10 1016 j bbamem 2004 12 011 PMID 15737334 Otsuki T Ota T Nishikawa T et al 2007 Signal sequence and keyword trap in silico for selection of full length human cDNAs encoding secretion or membrane proteins from oligo capped cDNA libraries DNA Res 12 2 117 26 doi 10 1093 dnares 12 2 117 PMID 16303743 Rotmann A Vekony N Gassner D et al 2006 Activation of classical protein kinase C reduces the expression of human cationic amino acid transporter 3 hCAT 3 in the plasma membrane Biochem J 395 1 117 23 doi 10 1042 BJ20051558 PMC 1409692 PMID 16332251 This article incorporates text from the United States National Library of Medicine which is in the public domain This membrane protein related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Cationic amino acid 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