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López-Ríos J, Tessmar K, Loosli F, et al. (2003). "Six3 and Six6 activity is modulated by members of the groucho family". Development. 130 (1): 185–95. doi:10.1242/dev.00185. PMID 12441302.
Ikeda K, Watanabe Y, Ohto H, Kawakami K (2002). "Molecular interaction and synergistic activation of a promoter by Six, Eya, and Dach proteins mediated through CREB binding protein". Mol. Cell. Biol. 22 (19): 6759–66. doi:10.1128/MCB.22.19.6759-6766.2002. PMC134036. PMID 12215533.
Buller C, Xu X, Marquis V, et al. (2002). "Molecular effects of Eya1 domain mutations causing organ defects in BOR syndrome". Hum. Mol. Genet. 10 (24): 2775–81. doi:10.1093/hmg/10.24.2775. PMID 11734542.
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Celli J, van Beusekom E, Hennekam RC, et al. (2000). "Familial syndromic esophageal atresia maps to 2p23-p24". Am. J. Hum. Genet. 66 (2): 436–44. doi:10.1086/302779. PMC1288096. PMID 10677303.
Kawakami K, Ohto H, Takizawa T, Saito T (1996). "Identification and expression of six family genes in mouse retina". FEBS Lett. 393 (2–3): 259–63. doi:10.1016/0014-5793(96)00899-X. PMID 8814301. S2CID 20829948.
This article on a gene on human chromosome 2 is a stub. You can help Wikipedia by expanding it.
six2, homeobox, protein, protein, that, humans, encoded, gene, identifiersaliases, homeobox, 2external, idsomim, 604994, 102778, homologene, 56518, genecards, gene, location, human, chromosome, human, band2p21start45, end45, gene, location, mouse, chromosome, . Homeobox protein SIX2 is a protein that in humans is encoded by the SIX2 gene 5 6 SIX2IdentifiersAliasesSIX2 SIX homeobox 2External IDsOMIM 604994 MGI 102778 HomoloGene 56518 GeneCards SIX2Gene location Human Chr Chromosome 2 human 1 Band2p21Start45 005 182 bp 1 End45 009 452 bp 1 Gene location Mouse Chr Chromosome 17 mouse 2 Band17 E4 17 55 72 cMStart85 991 705 bp 2 End85 995 702 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed ingastrocnemius muscleparotid glandtibialis anterior musclepalpebral conjunctivapituitary glandperiodontal fiberislet of LangerhansAchilles tendonanterior pituitarydeltoid muscleTop expressed inmaxillary prominenceparotid glandexternal carotid arteryinternal carotid arteryurethrautriclemolarsacculemale urethraconjunctival fornixMore reference expression dataBioGPSMore reference expression dataGene ontologyMolecular functionDNA binding sequence specific DNA binding DNA binding transcription factor activity DNA binding transcription activator activity RNA polymerase II specific transcription factor binding RNA polymerase II cis regulatory region sequence specific DNA binding protein containing complex binding DNA binding transcription factor activity RNA polymerase II specific transcription cis regulatory region bindingCellular componentnucleus transcription regulator complexBiological processembryonic skeletal system morphogenesis regulation of chondrocyte differentiation regulation of transcription DNA templated positive regulation of chondrocyte proliferation chondrocyte differentiation protein import into nucleus kidney development negative regulation of cell differentiation anatomical structure morphogenesis mesenchymal stem cell maintenance involved in nephron morphogenesis mesenchymal to epithelial transition involved in metanephros morphogenesis mesenchymal cell differentiation involved in kidney development mesenchymal stem cell proliferation transcription by RNA polymerase II regulation of branching involved in ureteric bud morphogenesis multicellular organism development nephron morphogenesis nephron development middle ear morphogenesis embryonic digestive tract morphogenesis embryonic cranial skeleton morphogenesis regulation of ossification cell population proliferation mesodermal cell fate specification anterior posterior axis specification metanephros development cell migration positive regulation of transcription by RNA polymerase II condensed mesenchymal cell proliferation negative regulation of transcription DNA templated anatomical structure developmentSources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez1073620472EnsemblENSG00000170577ENSMUSG00000024134UniProtQ9NPC8Q8TBA2Q62232RefSeq mRNA NM 016932NM 011380RefSeq protein NP 058628NP 058628 3NP 035510Location UCSC Chr 2 45 01 45 01 MbChr 17 85 99 86 MbPubMed search 3 4 WikidataView Edit HumanView Edit MouseReferences edit a b c GRCh38 Ensembl release 89 ENSG00000170577 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000024134 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Entrez Gene SIX2 sine oculis homeobox homolog 2 Drosophila Oliver Guillermo 1995 Homeobox genes and connective tissue patterning PDF Development 121 3 693 705 doi 10 1242 dev 121 3 693 hdl 11858 00 001M 0000 0013 037D E PMID 7720577 Further reading editStrausberg RL Feingold EA Grouse LH et al 2003 Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 99 26 16899 903 Bibcode 2002PNAS 9916899M doi 10 1073 pnas 242603899 PMC 139241 PMID 12477932 Lopez Rios J Tessmar K Loosli F et al 2003 Six3 and Six6 activity is modulated by members of the groucho family Development 130 1 185 95 doi 10 1242 dev 00185 PMID 12441302 Ikeda K Watanabe Y Ohto H Kawakami K 2002 Molecular interaction and synergistic activation of a promoter by Six Eya and Dach proteins mediated through CREB binding protein Mol Cell Biol 22 19 6759 66 doi 10 1128 MCB 22 19 6759 6766 2002 PMC 134036 PMID 12215533 Buller C Xu X Marquis V et al 2002 Molecular effects of Eya1 domain mutations causing organ defects in BOR syndrome Hum Mol Genet 10 24 2775 81 doi 10 1093 hmg 10 24 2775 PMID 11734542 Boucher CA Winchester CL Hamilton GM et al 2000 Structure mapping and expression of the human gene encoding the homeodomain protein SIX2 Gene 247 1 2 145 51 doi 10 1016 S0378 1119 00 00105 0 PMID 10773454 Celli J van Beusekom E Hennekam RC et al 2000 Familial syndromic esophageal atresia maps to 2p23 p24 Am J Hum Genet 66 2 436 44 doi 10 1086 302779 PMC 1288096 PMID 10677303 Kawakami K Ohto H Takizawa T Saito T 1996 Identification and expression of six family genes in mouse retina FEBS Lett 393 2 3 259 63 doi 10 1016 0014 5793 96 00899 X PMID 8814301 S2CID 20829948 nbsp This article on a gene on human chromosome 2 is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title SIX2 amp oldid 1170133010, wikipedia, wiki, book, books, library,
