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Wikipedia

SERTAD1

April 15, 2024

SERTA domain-containing protein 1 is a protein that in humans is encoded by the SERTAD1 gene.[5][6][7]

SERTAD1
Identifiers
AliasesSERTAD1, SEI1, TRIP-Br1, SERTA domain containing 1, TRIPBR1
External IDsOMIM: 617850 MGI: 1913438 HomoloGene: 8365 GeneCards: SERTAD1
Orthologs
SpeciesHumanMouse
Entrez

29950

55942

Ensembl

ENSG00000197019

ENSMUSG00000008384

UniProt

Q9UHV2
Q53GC0

Q9JL10

RefSeq (mRNA)

NM_013376

NM_018820

RefSeq (protein)

NP_037508
NP_037508.2

NP_061290

Location (UCSC)Chr 19: 40.42 – 40.43 MbChr 7: 27.19 – 27.19 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions edit

SERTAD1 has been shown to interact with:

References edit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000197019 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000008384 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Besley GT, Broadhead DM, Lawlor E (Nov 1984). "Acid Esterase Deficiency: Comparison of Biochemical Findings in Infantile and Adult Forms". Organic Acidurias. Vol. 7. pp. 155–6. doi:10.1007/978-94-009-5612-4_52. ISBN 978-94-010-8975-3. PMID 6434876. {{cite book}}: |journal= ignored (help)
  6. ^ a b c Sugimoto M, Nakamura T, Ohtani N, Hampson L, Hampson IN, Shimamoto A, Furuichi Y, Okumura K, Niwa S, Taya Y, Hara E (Jan 2000). "Regulation of CDK4 activity by a novel CDK4-binding protein, p34SEI-1". Genes Dev. 13 (22): 3027–33. doi:10.1101/gad.13.22.3027. PMC 317153. PMID 10580009.
  7. ^ "Entrez Gene: SERTAD1 SERTA domain containing 1".
  8. ^ Hirose T, Fujii R, Nakamura H, Aratani S, Fujita H, Nakazawa M, Nakamura K, Nishioka K, Nakajima T (Jun 2003). "Regulation of CREB-mediated transcription by association of CDK4 binding protein p34SEI-1 with CBP". Int. J. Mol. Med. 11 (6): 705–12. doi:10.3892/ijmm.11.6.705. PMID 12736710.
  9. ^ a b Li J, Melvin WS, Tsai MD, Muscarella P (Apr 2004). "The nuclear protein p34SEI-1 regulates the kinase activity of cyclin-dependent kinase 4 in a concentration-dependent manner". Biochemistry. 43 (14): 4394–9. doi:10.1021/bi035601s. PMID 15065884.

Further reading edit

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Hsu SI, Yang CM, Sim KG, Hentschel DM, O'Leary E, Bonventre JV (2001). "TRIP-Br: a novel family of PHD zinc finger- and bromodomain-interacting proteins that regulate the transcriptional activity of E2F-1/DP-1". EMBO J. 20 (9): 2273–85. doi:10.1093/emboj/20.9.2273. PMC 125435. PMID 11331592.
  • Hirose T, Fujii R, Nakamura H, Aratani S, Fujita H, Nakazawa M, Nakamura K, Nishioka K, Nakajima T (2004). "Regulation of CREB-mediated transcription by association of CDK4 binding protein p34SEI-1 with CBP". Int. J. Mol. Med. 11 (6): 705–12. doi:10.3892/ijmm.11.6.705. PMID 12736710.
  • Gupta S, Takhar PP, Degenkolbe R, Koh CH, Zimmermann H, Yang CM, Guan Sim K, Hsu SI, Bernard HU (2004). "The human papillomavirus type 11 and 16 E6 proteins modulate the cell-cycle regulator and transcription cofactor TRIP-Br1". Virology. 317 (1): 155–64. doi:10.1016/j.virol.2003.08.008. PMID 14675634.
  • Li J, Melvin WS, Tsai MD, Muscarella P (2004). "The nuclear protein p34SEI-1 regulates the kinase activity of cyclin-dependent kinase 4 in a concentration-dependent manner". Biochemistry. 43 (14): 4394–9. doi:10.1021/bi035601s. PMID 15065884.
  • Li J, Muscarella P, Joo SH, Knobloch TJ, Melvin WS, Weghorst CM, Tsai MD (2006). "Dissection of CDK4-binding and transactivation activities of p34(SEI-1) and comparison between functions of p34(SEI-1) and p16(INK4A)". Biochemistry. 44 (40): 13246–56. doi:10.1021/bi0504658. PMID 16201750.
  • Otsuki T, Ota T, Nishikawa T, Hayashi K, Suzuki Y, Yamamoto J, Wakamatsu A, Kimura K, Sakamoto K, Hatano N, Kawai Y, Ishii S, Saito K, Kojima S, Sugiyama T, Ono T, Okano K, Yoshikawa Y, Aotsuka S, Sasaki N, Hattori A, Okumura K, Nagai K, Sugano S, Isogai T (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
  • Lim J, Hao T, Shaw C, Patel AJ, Szabó G, Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, Barabási AL, Vidal M, Zoghbi HY (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. S2CID 13709685.


 

This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by expanding it.

April 15, 2024
sertad1, serta, domain, containing, protein, protein, that, humans, encoded, gene, identifiersaliases, sei1, trip, serta, domain, containing, tripbr1external, idsomim, 617850, 1913438, homologene, 8365, genecards, gene, location, human, chromosome, human, band. SERTA domain containing protein 1 is a protein that in humans is encoded by the SERTAD1 gene 5 6 7 SERTAD1IdentifiersAliasesSERTAD1 SEI1 TRIP Br1 SERTA domain containing 1 TRIPBR1External IDsOMIM 617850 MGI 1913438 HomoloGene 8365 GeneCards SERTAD1Gene location Human Chr Chromosome 19 human 1 Band19q13 2Start40 421 589 bp 1 End40 425 992 bp 1 Gene location Mouse Chr Chromosome 7 mouse 2 Band7 7 A3Start27 186 335 bp 2 End27 189 741 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed invena cavaamniotic fluidlower lobe of lungsaphenous veintracheatibialis anterior musclepancreatic epithelial cellgastric mucosapericardiumnippleTop expressed inintestinal villusascending aortaaortic valvesciatic nervelipgastric mucosamucous cell of stomachepithelium of stomachileumskin of backMore reference expression dataBioGPSMore reference expression dataGene ontologyMolecular functionprotein bindingCellular componentcytoplasm nucleusBiological processpositive regulation of transcription DNA templated positive regulation of cell population proliferation positive regulation of transcription by RNA polymerase II transcription DNA templated regulation of cyclin dependent protein serine threonine kinase activity regulation of transcription DNA templated negative regulation of cell growthSources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez2995055942EnsemblENSG00000197019ENSMUSG00000008384UniProtQ9UHV2Q53GC0Q9JL10RefSeq mRNA NM 013376NM 018820RefSeq protein NP 037508NP 037508 2NP 061290Location UCSC Chr 19 40 42 40 43 MbChr 7 27 19 27 19 MbPubMed search 3 4 WikidataView Edit HumanView Edit MouseInteractions editSERTAD1 has been shown to interact with CREB binding protein 8 Cyclin dependent kinase 4 6 9 and P16 6 9 References edit a b c GRCh38 Ensembl release 89 ENSG00000197019 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000008384 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Besley GT Broadhead DM Lawlor E Nov 1984 Acid Esterase Deficiency Comparison of Biochemical Findings in Infantile and Adult Forms Organic Acidurias Vol 7 pp 155 6 doi 10 1007 978 94 009 5612 4 52 ISBN 978 94 010 8975 3 PMID 6434876 a href Template Cite book html title Template Cite book cite book a journal ignored help a b c Sugimoto M Nakamura T Ohtani N Hampson L Hampson IN Shimamoto A Furuichi Y Okumura K Niwa S Taya Y Hara E Jan 2000 Regulation of CDK4 activity by a novel CDK4 binding protein p34SEI 1 Genes Dev 13 22 3027 33 doi 10 1101 gad 13 22 3027 PMC 317153 PMID 10580009 Entrez Gene SERTAD1 SERTA domain containing 1 Hirose T Fujii R Nakamura H Aratani S Fujita H Nakazawa M Nakamura K Nishioka K Nakajima T Jun 2003 Regulation of CREB mediated transcription by association of CDK4 binding protein p34SEI 1 with CBP Int J Mol Med 11 6 705 12 doi 10 3892 ijmm 11 6 705 PMID 12736710 a b Li J Melvin WS Tsai MD Muscarella P Apr 2004 The nuclear protein p34SEI 1 regulates the kinase activity of cyclin dependent kinase 4 in a concentration dependent manner Biochemistry 43 14 4394 9 doi 10 1021 bi035601s PMID 15065884 Further reading editMaruyama K Sugano S 1994 Oligo capping a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides Gene 138 1 2 171 4 doi 10 1016 0378 1119 94 90802 8 PMID 8125298 Suzuki Y Yoshitomo Nakagawa K Maruyama K Suyama A Sugano S 1997 Construction and characterization of a full length enriched and a 5 end enriched cDNA library Gene 200 1 2 149 56 doi 10 1016 S0378 1119 97 00411 3 PMID 9373149 Hsu SI Yang CM Sim KG Hentschel DM O Leary E Bonventre JV 2001 TRIP Br a novel family of PHD zinc finger and bromodomain interacting proteins that regulate the transcriptional activity of E2F 1 DP 1 EMBO J 20 9 2273 85 doi 10 1093 emboj 20 9 2273 PMC 125435 PMID 11331592 Hirose T Fujii R Nakamura H Aratani S Fujita H Nakazawa M Nakamura K Nishioka K Nakajima T 2004 Regulation of CREB mediated transcription by association of CDK4 binding protein p34SEI 1 with CBP Int J Mol Med 11 6 705 12 doi 10 3892 ijmm 11 6 705 PMID 12736710 Gupta S Takhar PP Degenkolbe R Koh CH Zimmermann H Yang CM Guan Sim K Hsu SI Bernard HU 2004 The human papillomavirus type 11 and 16 E6 proteins modulate the cell cycle regulator and transcription cofactor TRIP Br1 Virology 317 1 155 64 doi 10 1016 j virol 2003 08 008 PMID 14675634 Li J Melvin WS Tsai MD Muscarella P 2004 The nuclear protein p34SEI 1 regulates the kinase activity of cyclin dependent kinase 4 in a concentration dependent manner Biochemistry 43 14 4394 9 doi 10 1021 bi035601s PMID 15065884 Li J Muscarella P Joo SH Knobloch TJ Melvin WS Weghorst CM Tsai MD 2006 Dissection of CDK4 binding and transactivation activities of p34 SEI 1 and comparison between functions of p34 SEI 1 and p16 INK4A Biochemistry 44 40 13246 56 doi 10 1021 bi0504658 PMID 16201750 Otsuki T Ota T Nishikawa T Hayashi K Suzuki Y Yamamoto J Wakamatsu A Kimura K Sakamoto K Hatano N Kawai Y Ishii S Saito K Kojima S Sugiyama T Ono T Okano K Yoshikawa Y Aotsuka S Sasaki N Hattori A Okumura K Nagai K Sugano S Isogai T 2007 Signal sequence and keyword trap in silico for selection of full length human cDNAs encoding secretion or membrane proteins from oligo capped cDNA libraries DNA Res 12 2 117 26 doi 10 1093 dnares 12 2 117 PMID 16303743 Lim J Hao T Shaw C Patel AJ Szabo G Rual JF Fisk CJ Li N Smolyar A Hill DE Barabasi AL Vidal M Zoghbi HY 2006 A protein protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration Cell 125 4 801 14 doi 10 1016 j cell 2006 03 032 PMID 16713569 S2CID 13709685 nbsp This article on a gene on human chromosome 19 is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title SERTAD1 amp oldid 1194582376, wikipedia, wiki, book, books, library,

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