Zeta variant, also known as lineage P.2,[a] is a variant of SARS-CoV-2, the virus that causes COVID-19. It was first detected in the state of Rio de Janeiro; it harbors the E484K mutation, but not the N501Y and K417T mutations. It evolved independently in Rio de Janeiro without being directly related to the Gamma variant from Manaus.[1][2]
Under the simplified naming scheme proposed by the World Health Organization, P.2 was labeled "Zeta variant", and was considered a variant of interest (VOI), but not a variant of concern.[3] A second wave was preceded in November 2020 by an increase in the prevalence of the Zeta variant among genetic sequences from São Paulo state, deposited into the GISAID database.[4] As of July 2021, Zeta is no longer considered a variant of interest by the WHO.[5]
^. COV lineages. Archived from the original on April 28, 2021. Retrieved January 28, 2021. P.2… Alias of B.1.1.28.2, Brazilian lineage
^Voloch, Carolina M.; da Silva Francisco, Ronaldo; de Almeida, Luiz G. P.; Cardoso, Cynthia C.; Brustolini, Otavio J.; Gerber, Alexandra L.; Guimarães, Ana Paula de C.; Mariani, Diana; da Costa, Raissa Mirella; Ferreira, Orlando C.; Cavalcanti, Adriana Cony (April 26, 2021). "Genomic Characterization of a Novel SARS-CoV-2 Lineage from Rio de Janeiro, Brazil". Journal of Virology. 95 (10). doi:10.1128/JVI.00119-21. ISSN 0022-538X. PMC8139668. PMID 33649194.
^"Genomic characterisation of an emergent SARS-CoV-2 lineage in Manaus: preliminary findings". Virological. January 12, 2021. Retrieved June 26, 2021.
^Ranzani, Otavio (2021). "Effectiveness of the CoronaVac vaccine in the elderly population during a Gamma variant-associated epidemic of COVID-19 in Brazil". medRxiv10.1101/2021.05.19.21257472v3.
^"Tracking SARS-CoV-2 variants". who.int. World Health Organization.
^ ab"Spike Variants: Zeta variant, aka P.2". covdb.stanford.edu. Stanford University Coronavirus Antiviral & Resistance Database. July 1, 2021. Retrieved July 5, 2021.
^"SARS-CoV-2 Variant Classifications and Definitions". CDC.gov. Centers for Disease Control and Prevention. February 11, 2020. Retrieved July 5, 2021.
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sars, zeta, variant, zeta, variant, also, known, lineage, variant, sars, virus, that, causes, covid, first, detected, state, janeiro, harbors, e484k, mutation, n501y, k417t, mutations, evolved, independently, janeiro, without, being, directly, related, gamma, . Zeta variant also known as lineage P 2 a is a variant of SARS CoV 2 the virus that causes COVID 19 It was first detected in the state of Rio de Janeiro it harbors the E484K mutation but not the N501Y and K417T mutations It evolved independently in Rio de Janeiro without being directly related to the Gamma variant from Manaus 1 2 Under the simplified naming scheme proposed by the World Health Organization P 2 was labeled Zeta variant and was considered a variant of interest VOI but not a variant of concern 3 A second wave was preceded in November 2020 by an increase in the prevalence of the Zeta variant among genetic sequences from Sao Paulo state deposited into the GISAID database 4 As of July 2021 Zeta is no longer considered a variant of interest by the WHO 5 Mutations editThe Zeta genome has 3 amino acid mutations E484K D614G and V1176F all of which are found in the virus s spike protein code 6 According to the Centers for Disease Control and Prevention F565L has been detected in some of the Zeta variant sequences but not all 7 nbsp Amino acid mutations of SARS CoV 2 Zeta variant plotted on a genome map of SARS CoV 2 with a focus on the spike 6 Notes edit A sub lineage of B 1 1 28References edit PANGO lineages Lineage P 2 COV lineages Archived from the original on April 28 2021 Retrieved January 28 2021 P 2 Alias of B 1 1 28 2 Brazilian lineage Voloch Carolina M da Silva Francisco Ronaldo de Almeida Luiz G P Cardoso Cynthia C Brustolini Otavio J Gerber Alexandra L Guimaraes Ana Paula de C Mariani Diana da Costa Raissa Mirella Ferreira Orlando C Cavalcanti Adriana Cony April 26 2021 Genomic Characterization of a Novel SARS CoV 2 Lineage from Rio de Janeiro Brazil Journal of Virology 95 10 doi 10 1128 JVI 00119 21 ISSN 0022 538X PMC 8139668 PMID 33649194 Genomic characterisation of an emergent SARS CoV 2 lineage in Manaus preliminary findings Virological January 12 2021 Retrieved June 26 2021 Ranzani Otavio 2021 Effectiveness of the CoronaVac vaccine in the elderly population during a Gamma variant associated epidemic of COVID 19 in Brazil medRxiv 10 1101 2021 05 19 21257472v3 Tracking SARS CoV 2 variants who int World Health Organization a b Spike Variants Zeta variant aka P 2 covdb stanford edu Stanford University Coronavirus Antiviral amp Resistance Database July 1 2021 Retrieved July 5 2021 SARS CoV 2 Variant Classifications and Definitions CDC gov Centers for Disease Control and Prevention February 11 2020 Retrieved July 5 2021 nbsp This article about the COVID 19 pandemic is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title SARS CoV 2 Zeta variant amp oldid 1179877276, wikipedia, wiki, book, books, library,
