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Russell Morse Wilder

April 14, 2024

Russell Morse Wilder Sr. (November 24, 1885 – December 16, 1959)[1] was an American physician, diabetologist, epileptologist, and medical researcher, known as one of the originators of the ketogenic ("classic keto") diet as a therapy for both epilepsy[2][3] and diabetes.[4][5] He coined the term "ketogenic diet."[2] He was also among the first American physicians to use insulin for patients with diabetes.[5]

Russell Morse Wilder
BornNovember 24, 1885
Cincinnati, Ohio
DiedDecember 16, 1959
Rochester, Minnesota
OccupationPhysician

Biography edit

At the University of Chicago he graduated with a B.S. in 1907 and with a Ph.D. in pathology in 1911. At Rush Medical College he was an instructor from 1909 to 1910 in pathology and anatomy and graduated there in 1911 with an M.D.[6] (Rush Medical College was affiliated with the University of Chicago until 1942.) During his undergraduate study he spent a year at Heidelberg University. As a medical student, he went to Mexico City in December 1909 with the physician and medical researcher Howard Taylor Ricketts to study typhus fever in the Valley of Mexico. Ricketts died of the disease on May 5, 1910, but Wilder returned to Mexico to carry on the research. He studied for eight months in 1914 in Vienna, principally at the First Medical Clinic under the pathologist Albert Müller-Deham (1881–1971), who had studied as a medical assistant under Carl von Noorden. Upon his return from Vienna, Wilder became a physician at Chicago's Presbyterian Hospital,[1] where he worked from 1914 to 1917[6] and completed his medical residency.[1] While he worked at Presbyterian Hospital, he was a fellow at the Sprague Memorial Institute from 1915 to 1917.[6]

At the Mayo Clinic, Wilder was a staff member from 1919 to 1929[6] and was section head for all the diabetic patients.[1] At the Mayo Foundation he was an assistant professor from 1919 to 1922 and an associate professor from 1922 to 1929.[6] From 1929 to 1931 he was a professor of medicine and chair of the department of medicine at the University of Chicago. In 1931 he rejoined the staff of the Mayo Clinic and became, at the Mayo Foundation, a full professor and head of the department of medicine. At the Mayo Clinic he investigated clinical problems of metabolism and nutrition. In 1950 he retired from the Mayo Clinic and Mayo Foundation to become the first director of the newly formed National Institute of Arthritis and Metabolic Diseases. In 1953, due to health problems, he retired as the institute's director and returned to Rochester, Minnesota.[1]

Wilder was the author or co-author of more than 250 papers and contributed to several medical textbooks and to the Encyclopaedia Britannica. He served "at various times on the editorial board of the Journal of Nutrition and the Archives of Internal Medicine, the editorial committee of Nutrition Reviews and as an associate editor of Public Health Reports."[1] He used his expertise in medicine and nutrition to serve the U.S. Federal government in several committees and agencies, especially during WW II.[1] For a one-year term from 1946 to 1947 he was the president of the American Diabetes Association.[1] In 1950 he delivered the Frank Billings Lecture.[7] In 1954 he received the American Medical Association's Joseph Goldberger Award in Clinical Nutrition. In 1956 he was the president of the National Vitamin Foundation, which in 1954 created the Russell M. Wilder Fellowship. In 1956 he received an award from the American Bakers Association "in recognition of his leadership in promoting enrichment of white flour and bread with vitamins."[1]

On March 18, 1911, in Butler, Ohio, he married Lucy Elizabeth Beeler (1889–1968). Upon his death he was survived by his widow and two sons, Russell Morse Wilder, Jr., M.D. (1912–1979) and Thomas Carroll Wilder, M.D. (1915–1961).

Selected publications edit

Articles edit

  • Ricketts, H. T.; Wilder, R. M. (1910). "The Typhus Fever of Mexico (Tarbadillo)". Journal of the American Medical Association (6): 463–467. doi:10.1001/jama.1910.92550320009002o.
  • Ricketts, H. T.; Wilder, R. M. (1910). "The Transmission of the Typhus Fever of Mexico (Tabardillo) by Means of the Louse (Pediculus Vestamenti)". Journal of the American Medical Association (16): 1304–1307. doi:10.1001/jama.1910.92550420001001h.
  • Ricketts, H. T.; Wilder, R. M. (1910). "The Etiology of the Typhus Fever (Tabardillo) of Mexico City". Journal of the American Medical Association (17): 1373–1375. doi:10.1001/jama.1910.92550430001001o.
  • Ricketts, H. T.; Wilder, R. M. (1910). "The Relation of Typhus Fever (Tabardillo) to Rocky Mountain Spotted Fever". Archives of Internal Medicine. V (4): 361–370. doi:10.1001/archinte.1910.00050260038003.
  • Wilder, Russell M. (1917). "d-Glucose tolerance in health and disease". Archives of Internal Medicine (2): 311–334. doi:10.1001/archinte.1917.00080210152008.
  • Russell M. Wilder (1924) [reprinted from Minnesota Medicine, 1923, vi, 524–529]. "How is the overworked general practitioner to use insulin?". In M. H. Mellish (ed.). Collected Papers of the Mayo Clinic and the Mayo Foundation. Vol. XV. W. B. Saunders. pp. 645–655.
  • Wilder, Russell M. (1926). "Hyperthyroidism, Myxedema and Diabetes". Archives of Internal Medicine. 38 (6): 736–760. doi:10.1001/archinte.1926.00120300053005.
  • Wilder, Russell M.; Allan, Frank N.; Power, M. H.; Robertson, H. E. (1927). "Carcinoma of the Islands of the Pancreas". Journal of the American Medical Association. 89 (5): 348–355. doi:10.1001/jama.1927.02690050014007.
  • Woltman, Henry W.; Wilder, R. M. (1929). "Diabetes Mellitus". Archives of Internal Medicine. 44 (4): 576–603. doi:10.1001/archinte.1929.00140040114010.
  • Wilder, Russell M. (1929). "Hyperparathyroidism: Tumor of the Parathyroid Glands Associated with Osteitis Fibrosa". Endocrinology. 13 (3): 231–244. doi:10.1210/endo-13-3-231.
  • Wagener, Henry P.; Dry, Thomas J. Story; Wilder, Russell M. (1934). "Retinitis in Diabetes". New England Journal of Medicine. 211 (25): 1131–1137. doi:10.1056/NEJM193412202112502.
  • Sprague, R.G.; Blum, B.B.; Osterberg, A.E.; Kepler, E.J.; Wilder, R.M. (1936). "Clinical Observations with Insulin Protamine Compound". Journal of the American Medical Association. 106 (20): 1701–1705. doi:10.1001/jama.1936.02770200007003.
  • Wilder, R. M.; Kendall, E. C.; Snell, A. M.; Kepler, E. J.; Rynearson, E. H.; Adams, M. (1937). "Intake of Potassium, an Important Consideration in Addison's Disease". Archives of Internal Medicine. 59 (3): 367–393. doi:10.1001/archinte.1937.00170190002001.
  • Cutler, Haydn H.; Power, M. H.; Wilder, R. H. (1938). "Concentrations of Chloride, Sodium and Potassium in Urine and Blood". Journal of the American Medical Association. 111 (2): 117–122. doi:10.1001/jama.1938.02790280007002.
  • Williams, R. D.; Mason, H. L.; Wilder, R. M.; Smith, B. F. (1940). "Observations on Induced Thiamine (Vitamin B1) Deficiency in Man". Archives of Internal Medicine. 66 (4): 785–799. doi:10.1001/archinte.1940.00190160002001.
  • Williams, R. D.; Mason, H. L.; Smith, B. F.; Wilder, R. M. (1942). "Induced Thiamine (Vitamin B1) Deficiency and the Thiamine Requirement of Man". Archives of Internal Medicine. 69 (5): 721–738. doi:10.1001/archinte.1942.00200170003001.
  • Williams, R. D.; Mason, H. L.; Power, M. H.; Wilder, R. M. (1943). "Induced Thiamine (Vitamin B1) Deficiency in Man". Archives of Internal Medicine. 71: 38–53. doi:10.1001/archinte.1943.00210010044003.
  • Williams, Ray D.; Mason, Harold L.; Cusick, Paul L.; Wilder, Russell M. (1943). "Observations on Induced Riboflavin Deficiency and the Riboflavin Requirement of Man". The Journal of Nutrition. 25 (4): 361–377. doi:10.1093/jn/25.4.361.
  • Adamson, J. D.; Jolliffe, N.; Kruse, H. D.; Lowry, O. H.; Moore, P. E.; Platt, B. S.; Sebrell, W. H.; Tice, J. W.; Tisdall, F. F.; Wilder, R. M.; Zamecnik, P. C. (1945). "Medical Survey of Nutrition in Newfoundland". Canadian Medical Association Journal. 52 (3): 227–250. PMC 1582114. PMID 20323369.
  • Wilder, Russell M. (1948). "The Unknown Diabetic and How to Recognize Him". Journal of the American Medical Association. 138 (5): 349–51, Disc., 355. doi:10.1001/jama.1948.02900050017005. PMID 18881479.
  • Aykroyd, W.R.; Jolliffe, N.; Lowry, O.H.; Moore, P.E.; Sebrell, W.H.; Shank, R.E.; Tisdall, F.F. (1949). "Medical resurvey of nutrition in Newfoundland 1948". Canadian Medical Association Journal. 60 (4): 329–352. PMC 1591368. PMID 18113857.
  • Steinberg, A. G.; Wilder, R. M. (1952). "A study of the genetics of diabetes mellitus". American Journal of Human Genetics. 4 (2): 113–135. PMC 1716433. PMID 14943712.

Books edit

  • Wilder, Russell Morse; Foley, Mary A.; Ellithorpe, Daisy (1921). A Primer for Diabetic Patients: A Brief Outline of the Principles of Diabetic Treatment, Sample Menus, Recipes and Food Tables. W. B. Saunders; 76 pages; 5th edition (1934). 172 pages[8]

References edit

  1. ^ a b c d e f g h i Sprague, Randall G. (1960). "Russell Morse Wilder, Sr. 1885–1959". Diabetes. 9 (5): 419–420. doi:10.2337/diab.9.5.419. S2CID 88436752.
  2. ^ a b Wheless, James W. (2008). "History of the ketogenic diet". Epilepsia. 49: 3–5. doi:10.1111/j.1528-1167.2008.01821.x. PMID 19049574. S2CID 45340697.
  3. ^ Höhn, Sophie; Dozières-Puyravel, Blandine; Auvin, Stéphane (2019). "History of dietary treatment from Wilder's hypothesis to the first open studies in the 1920s". Epilepsy & Behavior. 101 (Pt A): 106588. doi:10.1016/j.yebeh.2019.106588. PMID 31677579. S2CID 204963505.
  4. ^ Macleod, John James Rickard; Campbell, Walter Ruggles (1925). Insulin: Its Use in the Treatment of Diabetes. Williams & Wilkins. p. 124.
  5. ^ a b "A Line in the Sand – Mayo Clinic's role in insulin research". Discovery's Edge, Mayo Clinic's Research Magazine. March 2015.
  6. ^ a b c d e Cattell, J., ed. (1949). American Men of Science: A Biographical Dictionary (8th ed.). Lancaster, Pennsylvania: The Science Press. p. 2706.
  7. ^ Wilder, Russell M. (1950). "Reflections on the Causation of Diabetes Mellitus". Journal of the American Medical Association. 144 (15): 1234–1238. doi:10.1001/jama.1950.02920150008003. PMID 14778728. (1950 Frank Billings Lecture)
  8. ^ Struve, Mildred (1935). "Review of A Primer for Diabetic Patients by R. M. Wilder". American Journal of Nursing. 35 (7): 714. doi:10.2307/3411460. JSTOR 3411460.
  • Peter Wolf; Katia Lin; Marina Nikanorova (2013). "Non-Pharmacological Therapy". In Shorvon, Simon; Guerrinini, Renzo; Cook, Mark; Lhatoo, Samden D. (eds.). Oxford Textbook of Epilepsy and Epileptic Seizures. p. 140. ISBN 978-0-19-965904-3.

External links edit

  • "Russell M. Wilder, Evolution of Nutrition, Thursday, December 10, 1953, Lectures for the Laity". WNYC Radio.
  • Parmar, Arundhati (December 22, 2011). "The 50 best Mayo Clinic doctors. Ever". MedCity News, MinnPost.

April 14, 2024
russell, morse, wilder, november, 1885, december, 1959, american, physician, diabetologist, epileptologist, medical, researcher, known, originators, ketogenic, classic, keto, diet, therapy, both, epilepsy, diabetes, coined, term, ketogenic, diet, also, among, . Russell Morse Wilder Sr November 24 1885 December 16 1959 1 was an American physician diabetologist epileptologist and medical researcher known as one of the originators of the ketogenic classic keto diet as a therapy for both epilepsy 2 3 and diabetes 4 5 He coined the term ketogenic diet 2 He was also among the first American physicians to use insulin for patients with diabetes 5 Russell Morse WilderBornNovember 24 1885Cincinnati OhioDiedDecember 16 1959Rochester MinnesotaOccupationPhysician Contents 1 Biography 2 Selected publications 2 1 Articles 2 2 Books 3 References 4 External linksBiography editAt the University of Chicago he graduated with a B S in 1907 and with a Ph D in pathology in 1911 At Rush Medical College he was an instructor from 1909 to 1910 in pathology and anatomy and graduated there in 1911 with an M D 6 Rush Medical College was affiliated with the University of Chicago until 1942 During his undergraduate study he spent a year at Heidelberg University As a medical student he went to Mexico City in December 1909 with the physician and medical researcher Howard Taylor Ricketts to study typhus fever in the Valley of Mexico Ricketts died of the disease on May 5 1910 but Wilder returned to Mexico to carry on the research He studied for eight months in 1914 in Vienna principally at the First Medical Clinic under the pathologist Albert Muller Deham 1881 1971 who had studied as a medical assistant under Carl von Noorden Upon his return from Vienna Wilder became a physician at Chicago s Presbyterian Hospital 1 where he worked from 1914 to 1917 6 and completed his medical residency 1 While he worked at Presbyterian Hospital he was a fellow at the Sprague Memorial Institute from 1915 to 1917 6 At the Mayo Clinic Wilder was a staff member from 1919 to 1929 6 and was section head for all the diabetic patients 1 At the Mayo Foundation he was an assistant professor from 1919 to 1922 and an associate professor from 1922 to 1929 6 From 1929 to 1931 he was a professor of medicine and chair of the department of medicine at the University of Chicago In 1931 he rejoined the staff of the Mayo Clinic and became at the Mayo Foundation a full professor and head of the department of medicine At the Mayo Clinic he investigated clinical problems of metabolism and nutrition In 1950 he retired from the Mayo Clinic and Mayo Foundation to become the first director of the newly formed National Institute of Arthritis and Metabolic Diseases In 1953 due to health problems he retired as the institute s director and returned to Rochester Minnesota 1 Wilder was the author or co author of more than 250 papers and contributed to several medical textbooks and to the Encyclopaedia Britannica He served at various times on the editorial board of the Journal of Nutrition and the Archives of Internal Medicine the editorial committee of Nutrition Reviewsand as an associate editor of Public Health Reports 1 He used his expertise in medicine and nutrition to serve the U S Federal government in several committees and agencies especially during WW II 1 For a one year term from 1946 to 1947 he was the president of the American Diabetes Association 1 In 1950 he delivered the Frank Billings Lecture 7 In 1954 he received the American Medical Association s Joseph Goldberger Award in Clinical Nutrition In 1956 he was the president of the National Vitamin Foundation which in 1954 created the Russell M Wilder Fellowship In 1956 he received an award from the American Bakers Association in recognition of his leadership in promoting enrichment of white flour and bread with vitamins 1 On March 18 1911 in Butler Ohio he married Lucy Elizabeth Beeler 1889 1968 Upon his death he was survived by his widow and two sons Russell Morse Wilder Jr M D 1912 1979 and Thomas Carroll Wilder M D 1915 1961 Selected publications editArticles edit Ricketts H T Wilder R M 1910 The Typhus Fever of Mexico Tarbadillo Journal of the American Medical Association 6 463 467 doi 10 1001 jama 1910 92550320009002o Ricketts H T Wilder R M 1910 The Transmission of the Typhus Fever of Mexico Tabardillo by Means of the Louse Pediculus Vestamenti Journal of the American Medical Association 16 1304 1307 doi 10 1001 jama 1910 92550420001001h Ricketts H T Wilder R M 1910 The Etiology of the Typhus Fever Tabardillo of Mexico City Journal of the American Medical Association 17 1373 1375 doi 10 1001 jama 1910 92550430001001o Ricketts H T Wilder R M 1910 The Relation of Typhus Fever Tabardillo to Rocky Mountain Spotted Fever Archives of Internal Medicine V 4 361 370 doi 10 1001 archinte 1910 00050260038003 Wilder Russell M 1917 d Glucose tolerance in health and disease Archives of Internal Medicine 2 311 334 doi 10 1001 archinte 1917 00080210152008 Russell M Wilder 1924 reprinted from Minnesota Medicine 1923 vi 524 529 How is the overworked general practitioner to use insulin In M H Mellish ed Collected Papers of the Mayo Clinic and the Mayo Foundation Vol XV W B Saunders pp 645 655 Wilder Russell M 1926 Hyperthyroidism Myxedema and Diabetes Archives of Internal Medicine 38 6 736 760 doi 10 1001 archinte 1926 00120300053005 Wilder Russell M Allan Frank N Power M H Robertson H E 1927 Carcinoma of the Islands of the Pancreas Journal of the American Medical Association 89 5 348 355 doi 10 1001 jama 1927 02690050014007 Woltman Henry W Wilder R M 1929 Diabetes Mellitus Archives of Internal Medicine 44 4 576 603 doi 10 1001 archinte 1929 00140040114010 Wilder Russell M 1929 Hyperparathyroidism Tumor of the Parathyroid Glands Associated with Osteitis Fibrosa Endocrinology 13 3 231 244 doi 10 1210 endo 13 3 231 Wagener Henry P Dry Thomas J Story Wilder Russell M 1934 Retinitis in Diabetes New England Journal of Medicine 211 25 1131 1137 doi 10 1056 NEJM193412202112502 Sprague R G Blum B B Osterberg A E Kepler E J Wilder R M 1936 Clinical Observations with Insulin Protamine Compound Journal of the American Medical Association 106 20 1701 1705 doi 10 1001 jama 1936 02770200007003 Wilder R M Kendall E C Snell A M Kepler E J Rynearson E H Adams M 1937 Intake of Potassium an Important Consideration in Addison s Disease Archives of Internal Medicine 59 3 367 393 doi 10 1001 archinte 1937 00170190002001 Cutler Haydn H Power M H Wilder R H 1938 Concentrations of Chloride Sodium and Potassium in Urine and Blood Journal of the American Medical Association 111 2 117 122 doi 10 1001 jama 1938 02790280007002 Williams R D Mason H L Wilder R M Smith B F 1940 Observations on Induced Thiamine Vitamin B1 Deficiency in Man Archives of Internal Medicine 66 4 785 799 doi 10 1001 archinte 1940 00190160002001 Williams R D Mason H L Smith B F Wilder R M 1942 Induced Thiamine Vitamin B1 Deficiency and the Thiamine Requirement of Man Archives of Internal Medicine 69 5 721 738 doi 10 1001 archinte 1942 00200170003001 Williams R D Mason H L Power M H Wilder R M 1943 Induced Thiamine Vitamin B1 Deficiency in Man Archives of Internal Medicine 71 38 53 doi 10 1001 archinte 1943 00210010044003 Williams Ray D Mason Harold L Cusick Paul L Wilder Russell M 1943 Observations on Induced Riboflavin Deficiency and the Riboflavin Requirement of Man The Journal of Nutrition 25 4 361 377 doi 10 1093 jn 25 4 361 Adamson J D Jolliffe N Kruse H D Lowry O H Moore P E Platt B S Sebrell W H Tice J W Tisdall F F Wilder R M Zamecnik P C 1945 Medical Survey of Nutrition in Newfoundland Canadian Medical Association Journal 52 3 227 250 PMC 1582114 PMID 20323369 Wilder Russell M 1948 The Unknown Diabetic and How to Recognize Him Journal of the American Medical Association 138 5 349 51 Disc 355 doi 10 1001 jama 1948 02900050017005 PMID 18881479 Aykroyd W R Jolliffe N Lowry O H Moore P E Sebrell W H Shank R E Tisdall F F 1949 Medical resurvey of nutrition in Newfoundland 1948 Canadian Medical Association Journal 60 4 329 352 PMC 1591368 PMID 18113857 Steinberg A G Wilder R M 1952 A study of the genetics of diabetes mellitus American Journal of Human Genetics 4 2 113 135 PMC 1716433 PMID 14943712 Books edit Wilder Russell Morse Foley Mary A Ellithorpe Daisy 1921 A Primer for Diabetic Patients A Brief Outline of the Principles of Diabetic Treatment Sample Menus Recipes and Food Tables W B Saunders 76 pages 5th edition 1934 172 pages 8 References edit a b c d e f g h i Sprague Randall G 1960 Russell Morse Wilder Sr 1885 1959 Diabetes 9 5 419 420 doi 10 2337 diab 9 5 419 S2CID 88436752 a b Wheless James W 2008 History of the ketogenic diet Epilepsia 49 3 5 doi 10 1111 j 1528 1167 2008 01821 x PMID 19049574 S2CID 45340697 Hohn Sophie Dozieres Puyravel Blandine Auvin Stephane 2019 History of dietary treatment from Wilder s hypothesis to the first open studies in the 1920s Epilepsy amp Behavior 101 Pt A 106588 doi 10 1016 j yebeh 2019 106588 PMID 31677579 S2CID 204963505 Macleod John James Rickard Campbell Walter Ruggles 1925 Insulin Its Use in the Treatment of Diabetes Williams amp Wilkins p 124 a b A Line in the Sand Mayo Clinic s role in insulin research Discovery s Edge Mayo Clinic s Research Magazine March 2015 a b c d e Cattell J ed 1949 American Men of Science A Biographical Dictionary 8th ed Lancaster Pennsylvania The Science Press p 2706 Wilder Russell M 1950 Reflections on the Causation of Diabetes Mellitus Journal of the American Medical Association 144 15 1234 1238 doi 10 1001 jama 1950 02920150008003 PMID 14778728 1950 Frank Billings Lecture Struve Mildred 1935 Review of A Primer for Diabetic Patients by R M Wilder American Journal of Nursing 35 7 714 doi 10 2307 3411460 JSTOR 3411460 Peter Wolf Katia Lin Marina Nikanorova 2013 Non Pharmacological Therapy In Shorvon Simon Guerrinini Renzo Cook Mark Lhatoo Samden D eds Oxford Textbook of Epilepsy and Epileptic Seizures p 140 ISBN 978 0 19 965904 3 External links edit Russell M Wilder Evolution of Nutrition Thursday December 10 1953 Lectures for the Laity WNYC Radio Parmar Arundhati December 22 2011 The 50 best Mayo Clinic doctors Ever MedCity News MinnPost Retrieved from https en wikipedia org w index php title Russell Morse Wilder amp oldid 1205763303, wikipedia, wiki, book, books, library,

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