Río Hortega was born in Portillo, Valladolid on 5 May 1882.[1] He studied locally and qualified to practice medicine in 1905. He obtained his doctorate at the University of Madrid by researching the pathology of brain tumours. In 1913, he was funded to study research histology in France and Germany but the outbreak of war between them forced him to return to Spain.[1]
He managed to identify microglia between 1919 and 1921 by staining the cells with silver carbonate.[3] His method of staining also led to the discovery of oligodendroglia in 1921,[4] which both he and Penfield are now credited with.[2] However it was Rio Hortega who named the cells.[1]
His discoveries in 1920 created issues with Ramón y Cajal, who led the lab, as he had earlier won the Nobel Prize. By 1931 del Río Hortega was leading Spain's cancer institute, but he left the country when the civil war broke out in 1936.[1]
War spreading across Europe found him in Paris at the Pitié-Salpêtrière Hospital before he went to the University of Oxford to work with the British neurosurgeon Hugh Cairns.[5] The bombing of Britain by Germany in World War II drove him on to Argentina in August 1940. His move was funded by the Spanish Cultural Institute, who continued to support him as he created his own laboratory in 1942. In Buenos Aires he developed a fruitful scientific school with former disciples who worked with him in Europe (Moisés Polak,[6] Washington Buño[7]) and new ones, including chronologically the last one, Amanda Pellegrino de Iraldi.[8] Río Hortega died in Buenos Aires on 1 June 1945 from a malignant neoplasm.[1]
Referencesedit
Wikimedia Commons has media related to Pío del Río Hortega.
^ abcde"Historical perspective on oligodendrocytes and myelin". University of Illinois at Chicago. Retrieved 18 December 2012.
^ abGill, Amandip S.; Binder, Devin K. (1 May 2007). "Wilder Penfield, Pío Del Río-hortega, and the Discovery of Oligodendroglia". Neurosurgery. 60 (5): 940–948. doi:10.1227/01.NEU.0000255448.97730.34. PMID 17460531. S2CID 6282005.
^ ab"Pio del Rio Hortega". Encyclopædia Britannica. Retrieved 18 December 2012.
^James, Owen G; Mehta, Arpan R; Behari, Madhuri; Chandran, Siddharthan (June 2021). "Centenary of the oligodendrocyte". The Lancet Neurology. 20 (6): 422. doi:10.1016/S1474-4422(21)00136-8. PMC7610932. PMID 34022167.
^"Pío del Río Hortega (1882-1945)". Historia de la Medicina.
^Cruz-Sánchez (2002). "La escuela española de neurología cajaliana – La semilla iberoamericana" (PDF). Revista Española de Patología.
^Nombela, Cristina; Fernández-Egea, Emilio; Giné, Elena; Worbe, Yulia; del Río-Hortega Bereciartu, Juan; de Castro, Fernando (2021). "Women Neuroscientist Disciples of Pío del Río-Hortega: the Cajal School Spreads in Europe and South America". Frontiers in Neuroanatomy. 15. doi:10.3389/fnana.2021.666938. hdl:10261/249909. ISSN 1662-5129. PMID 34040507.
January 25, 2024
pío, río, hortega, 1882, 1945, spanish, neuroscientist, discovered, microglia, statue, outside, valladolid, science, museumborn5, 1882portillo, valladoliddied1, june, 1945, aged, buenos, airesnationalityspanishknown, fordiscovering, microgliabiography, editrío. Pio del Rio Hortega 1882 1945 was a Spanish neuroscientist who discovered microglia Pio del Rio HortegaStatue of Pio del Rio Hortega outside Valladolid Science MuseumBorn5 May 1882Portillo ValladolidDied1 June 1945 aged 63 Buenos AiresNationalitySpanishKnown fordiscovering microgliaBiography editRio Hortega was born in Portillo Valladolid on 5 May 1882 1 He studied locally and qualified to practice medicine in 1905 He obtained his doctorate at the University of Madrid by researching the pathology of brain tumours In 1913 he was funded to study research histology in France and Germany but the outbreak of war between them forced him to return to Spain 1 He worked with the histologist Santiago Ramon y Cajal and briefly with Wilder Penfield Ramon y Cajal discovered neurons Penfield helped explain oligodendroglia 2 whilst Rio Hortega discovered microglia 3 which are the cells that protect the brain from infection He managed to identify microglia between 1919 and 1921 by staining the cells with silver carbonate 3 His method of staining also led to the discovery of oligodendroglia in 1921 4 which both he and Penfield are now credited with 2 However it was Rio Hortega who named the cells 1 His discoveries in 1920 created issues with Ramon y Cajal who led the lab as he had earlier won the Nobel Prize By 1931 del Rio Hortega was leading Spain s cancer institute but he left the country when the civil war broke out in 1936 1 War spreading across Europe found him in Paris at the Pitie Salpetriere Hospital before he went to the University of Oxford to work with the British neurosurgeon Hugh Cairns 5 The bombing of Britain by Germany in World War II drove him on to Argentina in August 1940 His move was funded by the Spanish Cultural Institute who continued to support him as he created his own laboratory in 1942 In Buenos Aires he developed a fruitful scientific school with former disciples who worked with him in Europe Moises Polak 6 Washington Buno 7 and new ones including chronologically the last one Amanda Pellegrino de Iraldi 8 Rio Hortega died in Buenos Aires on 1 June 1945 from a malignant neoplasm 1 References edit nbsp Wikimedia Commons has media related to Pio del Rio Hortega a b c d e Historical perspective on oligodendrocytes and myelin University of Illinois at Chicago Retrieved 18 December 2012 a b Gill Amandip S Binder Devin K 1 May 2007 Wilder Penfield Pio Del Rio hortega and the Discovery of Oligodendroglia Neurosurgery 60 5 940 948 doi 10 1227 01 NEU 0000255448 97730 34 PMID 17460531 S2CID 6282005 a b Pio del Rio Hortega Encyclopaedia Britannica Retrieved 18 December 2012 James Owen G Mehta Arpan R Behari Madhuri Chandran Siddharthan June 2021 Centenary of the oligodendrocyte The Lancet Neurology 20 6 422 doi 10 1016 S1474 4422 21 00136 8 PMC 7610932 PMID 34022167 Pio del Rio Hortega 1882 1945 Historia de la Medicina Cruz Sanchez 2002 La escuela espanola de neurologia cajaliana La semilla iberoamericana PDF Revista Espanola de Patologia Bio bibliografia de Washington Buno PDF Nombela Cristina Fernandez Egea Emilio Gine Elena Worbe Yulia del Rio Hortega Bereciartu Juan de Castro Fernando 2021 Women Neuroscientist Disciples of Pio del Rio Hortega the Cajal School Spreads in Europe and South America Frontiers in Neuroanatomy 15 doi 10 3389 fnana 2021 666938 hdl 10261 249909 ISSN 1662 5129 PMID 34040507 Retrieved from https en wikipedia org w index php title Pio del Rio Hortega amp oldid 1193910587, wikipedia, wiki, book, books, library,
