Pyranocoumarin

Pyranocoumarins are a class of chemical compounds that have a core structure that consists of a pyran ring fused to a coumarin. As phytochemicals, pyranocoumarins are uncommon and found mainly the plant families Apiaceae and Rutaceae.^[1] For example, Citrus sinensis and Citrus limonia are sources of xanthyletin and seselin.^[2]

Chemical structures of xanthyletin (top) and seselin

In the biosyntheses of pyranocoumarins, the pyran ring is formed via the methylerythritol phosphate pathway and the coumarin is derived from the shikimate pathway.^[2]

See also

• Furanocoumarin

References

1. Khandy, Maria T.; Sofronova, Anastasia K.; Gorpenchenko, Tatiana Y.; Chirikova, Nadezhda K. (2022). "Plant Pyranocoumarins: Description, Biosynthesis, Application". Plants. 11 (22): 3135. doi:10.3390/plants11223135. PMC 9693251. PMID 36432864.
2. Amaral, Jéssica C.; Da Silva, Michelli M.; Da Silva, M. Fátima G. F.; Alves, Thayana C.; Ferreira, A. Gilberto; Forim, Moacir R.; Fernandes, João B.; Pina, Edieidia S.; Lopes, Adriana A.; Pereira, Ana M. S.; Novelli, Valdenice M. (2020). "Advances in the Biosynthesis of Pyranocoumarins: Isolation and 13C-Incorporation Analysis by High-Performance Liquid Chromatography–Ultraviolet–Solid-Phase Extraction–Nuclear Magnetic Resonance Data". Journal of Natural Products. 83 (5): 1409–1415. doi:10.1021/acs.jnatprod.9b00607. PMID 32372647. S2CID 218519965.