A plaque-forming unit (PFU) is a measure used in virology to describe the number of virus particles capable of forming plaques per unit volume. It is a proxy measurement rather than a measurement of the absolute quantity of particles: viral particles that are defective or which fail to infect their target cell will not produce a plaque and thus will not be counted.
For example, a solution of tick-borne encephalitis virus with a concentration of 1,000 PFU/μL indicates that 1 μL of the solution contains enough virus particles to produce 1000 infectious plaques in a cell mono-layer, but no inference can be made about the relationship of PFU to number of virus particles. The concept of plaque-forming units of virus is equivalent to the concept of colony-forming units of bacteria.
plaque, forming, unit, this, article, does, cite, sources, please, help, improve, this, article, adding, citations, reliable, sources, unsourced, material, challenged, removed, find, sources, news, newspapers, books, scholar, jstor, 2020, learn, when, remove, . This article does not cite any sources Please help improve this article by adding citations to reliable sources Unsourced material may be challenged and removed Find sources Plaque forming unit news newspapers books scholar JSTOR May 2020 Learn how and when to remove this template message A plaque forming unit PFU is a measure used in virology to describe the number of virus particles capable of forming plaques per unit volume It is a proxy measurement rather than a measurement of the absolute quantity of particles viral particles that are defective or which fail to infect their target cell will not produce a plaque and thus will not be counted For example a solution of tick borne encephalitis virus with a concentration of 1 000 PFU mL indicates that 1 mL of the solution contains enough virus particles to produce 1000 infectious plaques in a cell mono layer but no inference can be made about the relationship of PFU to number of virus particles The concept of plaque forming units of virus is equivalent to the concept of colony forming units of bacteria See also edit nbsp Viruses portalViral load Minimal infective dose Virus quantificationReferences edithttps www sciencedirect com topics immunology and microbiology plaque forming unitExternal links editDefinition from Biology Online org nbsp This virus related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Plaque forming unit amp oldid 1177514012, wikipedia, wiki, book, books, library,
