A report in the journal Inorganic Chemistry showed that in liquid solutions pirenoxine could cause decreased cloudiness of a crystallin solution produced to mimic the environment of the eye. Pirenoxine interacts with selenite or calcium ions that have been proven as factors leading to the formation of lens cataract.[1]
Pirenoxine reduces the cloudiness of the lens solution containing calcium by 38% and reduced the cloudiness of the selenite solution by 11%.[2]
“...there are not any proctored studies that prove the utility of these drops. In Canada and in the U.S. they are considered homeopathic—probably do no harm but doubtful that they will have any protective value."[3]
Referencesedit
^Liao JH, Chen CS, Hu CC, Chen WT, Wang SP, Lin IL, et al. (January 2011). "Ditopic complexation of selenite anions or calcium cations by pirenoxine: an implication for anti-cataractogenesis". Inorganic Chemistry. 50 (1): 365–77. doi:10.1021/ic102151p. PMID 21138325.
^Staff, R. O. "Can Chinese Drop Clear Cataracts?". www.reviewofoptometry.com. Retrieved 2022-07-15.
^Can Catalin Eye Drops Protect Eyes From Cataracts? Answered by Jeffrey Whitman MD OCS on Febr. 21, 2014 on the website of the American Academy of Ophthalmology.
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pirenoxine, abbreviated, trade, name, catalin, medication, used, possible, treatment, prevention, cataracts, clinical, datatrade, namescatalinatcvet, codeqs01xa91, identifiersiupac, name, dioxo, pyrido, phenoxazine, carboxylic, acidcas, number1043, 6pubchem, c. Pirenoxine abbreviated PRX trade name Catalin is a medication used in the possible treatment and prevention of cataracts PirenoxineClinical dataTrade namesCatalinATCvet codeQS01XA91 WHO IdentifiersIUPAC name 1 5 Dioxo 4H pyrido 3 2 a phenoxazine 3 carboxylic acidCAS Number1043 21 6PubChem CID4846ChemSpider4846UNII27L0EP6IZKCompTox Dashboard EPA DTXSID6048335ECHA InfoCard100 012 612Chemical and physical dataFormulaC 16H 8N 2O 5Molar mass308 249 g mol 13D model JSmol Interactive imageSMILES C1 CC C2C C1 N C3C CC O C4 C3C O C C N4 C O O O2InChI InChI 1S C16H8N2O5 c19 9 5 8 16 21 22 18 14 10 20 6 12 15 13 9 14 17 7 3 1 2 4 11 7 23 12 h1 6H H 18 19 H 21 22 Key OKPNYGAWTYOBFZ UHFFFAOYSA NA report in the journal Inorganic Chemistry showed that in liquid solutions pirenoxine could cause decreased cloudiness of a crystallin solution produced to mimic the environment of the eye Pirenoxine interacts with selenite or calcium ions that have been proven as factors leading to the formation of lens cataract 1 Pirenoxine reduces the cloudiness of the lens solution containing calcium by 38 and reduced the cloudiness of the selenite solution by 11 2 there are not any proctored studies that prove the utility of these drops In Canada and in the U S they are considered homeopathic probably do no harm but doubtful that they will have any protective value 3 References edit Liao JH Chen CS Hu CC Chen WT Wang SP Lin IL et al January 2011 Ditopic complexation of selenite anions or calcium cations by pirenoxine an implication for anti cataractogenesis Inorganic Chemistry 50 1 365 77 doi 10 1021 ic102151p PMID 21138325 Staff R O Can Chinese Drop Clear Cataracts www reviewofoptometry com Retrieved 2022 07 15 Can Catalin Eye Drops Protect Eyes From Cataracts Answered by Jeffrey Whitman MD OCS on Febr 21 2014 on the website of the American Academy of Ophthalmology nbsp This pharmacology related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Pirenoxine amp oldid 1183387402, wikipedia, wiki, book, books, library,
