Porfimer is a mixture of oligomers formed by ether and ester linkages of up to eight porphyrin units.[1] In practice, a red light source emitting at 630 nm is used to excite the Porfimer oligomers.[2]
It was approved in Canada in 1993 for the treatment of bladder cancer.[2] It was approved in Japan in 1994 (for early stage lung cancer?).[2] It was approved by the U.S. FDA in December 1995 for esophageal cancer, and in 1998, it was approved for the treatment of early non-small cell lung cancer.[2]
^"FDA Patient Safety News: Show #20, October 2003". October 2003. Retrieved 2009-08-17.
External linksedit
Photofrin
Photofrin marketing info
Side effects of PDT with Photofrin
History of Photofrin
January 01, 1970
porfimer, sodium, sold, photofrin, photosensitizer, used, photodynamic, therapy, radiation, therapy, palliative, treatment, obstructing, endobronchial, small, cell, lung, carcinoma, obstructing, esophageal, cancer, clinical, dataahfs, drugs, comconsumer, drug,. Porfimer sodium sold as Photofrin is a photosensitizer used in photodynamic therapy and radiation therapy and for palliative treatment of obstructing endobronchial non small cell lung carcinoma and obstructing esophageal cancer Porfimer sodiumClinical dataAHFS Drugs comConsumer Drug InformationLicense dataEU EMA by INN US FDA PhotofrinRoutes ofadministrationIntravenousATC codeL01XD01 WHO Legal statusLegal statusUS onlyPharmacokinetic dataBioavailabilityNAProtein binding 90 Elimination half life21 5 days mean ExcretionFecalIdentifiersCAS Number87806 31 3 Yethyl ether 97067 70 4 YPubChem CID57166DrugBankDB00707 NChemSpider10482283 YUNIIY3834SIK5Fethyl ether 625J2HS54G YChEMBLChEMBL1201707 NChemical and physical dataFormulaC 68H 74N 8O 11 for n 0 Molar mass1179 36 g mol for n 0 g mol 13D model JSmol Interactive imageSMILES Na CC O C1 C C C 2C C5NC CC4 NC CC 3NC C C1N 2 C C C 3CCC O O C CCC O O C4C C C C5C C OC C C6 C C C 7C C 10NC CC9 NC CC 8NC C C6N 7 C C C 8CCC O O C CCC O O C9C C C C 10C C OInChI InChI 1S C68H74N8O11 Na c1 29 41 13 17 61 79 80 53 28 56 44 16 20 64 85 86 32 4 48 72 56 24 59 68 36 8 52 76 59 25 58 65 37 9 77 33 5 49 73 58 21 45 29 69 53 40 12 87 39 11 67 35 7 50 22 46 30 2 42 14 18 62 81 82 54 70 46 27 55 43 15 19 63 83 84 31 3 47 71 55 23 57 66 38 10 78 34 6 51 74 57 26 60 67 75 50 h21 28 37 40 71 73 75 77 78H 13 20H2 1 12H3 H 79 80 H 81 82 H 83 84 H 85 86 q 1 b45 21 46 22 47 23 48 24 49 21 50 22 51 26 52 25 53 28 54 27 55 27 56 28 57 23 58 25 59 24 60 26 YKey CGQHMICGJYKFFJ ZLJVSRBASA N Y N Y what is this verify Porfimer is a mixture of oligomers formed by ether and ester linkages of up to eight porphyrin units 1 In practice a red light source emitting at 630 nm is used to excite the Porfimer oligomers 2 Porfimer is Haematoporphyrin Derivative HpD See PDT Approvals and indications editIt was approved in Canada in 1993 for the treatment of bladder cancer 2 It was approved in Japan in 1994 for early stage lung cancer 2 It was approved by the U S FDA in December 1995 for esophageal cancer and in 1998 it was approved for the treatment of early non small cell lung cancer 2 In August 2003 the FDA approved its use for Barrett s esophagus 3 References edit Porfimer injection Prescribing information PDF a b c d Usuda J Kato H Okunaka T Furukawa K Tsutsui H Yamada K et al June 2006 Photodynamic therapy PDT for lung cancers Journal of Thoracic Oncology 1 5 489 93 doi 10 1016 S1556 0864 15 31616 6 PMID 17409904 FDA Patient Safety News Show 20 October 2003 October 2003 Retrieved 2009 08 17 External links editPhotofrin Photofrin marketing info Side effects of PDT with Photofrin History of Photofrin Retrieved from https en wikipedia org w index php title Porfimer sodium amp oldid 1134851204, wikipedia, wiki, book, books, library,
