Phenicarbazide can be obtained by mixing phenylhydrazine with acetic acid in aqueous solution with the addition of potassium cyanide. It is also obtained from the reaction of phenylhydrazine with urea.[2]
Propertiesedit
Phenicarbazide is a flammable, hard to ignite, crystalline, beige solid that is practically insoluble in water. It decomposes on heating.[3]
Usesedit
Phenicarbazide is an intermediate in the syntheses of a series of chemical compounds by cyclocondensation reactions.[4] It was investigated as an analgesic and antipyretic in the 1970s and was used in combination preparations.
Referencesedit
^"Phenicarbazide". International Agency for Research on Cancer (IARC) - Summaries & Evaluations. 25 March 1998.
^Bruchhausen F, Ebel S, Hackenthal E, Holzgrabe U, Albinus M, Amschler G, Angerer E (1999). Hagers Handbuch der Pharmazeutischen Praxis : Stoffe L-Z Folgeband 5 (5. vollständig neubearbeitete Auflage ed.). Berlin, Heidelberg. p. 420. ISBN978-3-642-58388-9. OCLC 913646782.{{cite book}}: CS1 maint: location missing publisher (link)
phenicarbazide, semicarbazide, antipyretic, substance, carcinogenic, mice, clinical, dataother, names1, phenylsemicarbazide, kryogeninatc, codenoneidentifiersiupac, name, phenylhydrazinecarboxamidecas, number103, nchemspider54963, yunii1lr2578324keggc19498, nc. Phenicarbazide is a semicarbazide and an antipyretic substance It is carcinogenic in mice 1 PhenicarbazideClinical dataOther names1 Phenylsemicarbazide KryogeninATC codenoneIdentifiersIUPAC name 2 PhenylhydrazinecarboxamideCAS Number103 03 7 NChemSpider54963 YUNII1LR2578324KEGGC19498 NCompTox Dashboard EPA DTXSID9020245ECHA InfoCard100 002 794Chemical and physical dataFormulaC 7H 9N 3OMolar mass151 169 g mol 1InChI InChI 1S C7H9N3O c8 7 11 10 9 6 4 2 1 3 5 6 h1 5 9H H3 8 10 11 YKey AVKHCKXGKPAGEI UHFFFAOYSA N Y N Y what is this verify Contents 1 Preparation 2 Properties 3 Uses 4 ReferencesPreparation editPhenicarbazide can be obtained by mixing phenylhydrazine with acetic acid in aqueous solution with the addition of potassium cyanide It is also obtained from the reaction of phenylhydrazine with urea 2 Properties editPhenicarbazide is a flammable hard to ignite crystalline beige solid that is practically insoluble in water It decomposes on heating 3 Uses editPhenicarbazide is an intermediate in the syntheses of a series of chemical compounds by cyclocondensation reactions 4 It was investigated as an analgesic and antipyretic in the 1970s and was used in combination preparations References edit Phenicarbazide International Agency for Research on Cancer IARC Summaries amp Evaluations 25 March 1998 Bruchhausen F Ebel S Hackenthal E Holzgrabe U Albinus M Amschler G Angerer E 1999 Hagers Handbuch der Pharmazeutischen Praxis Stoffe L Z Folgeband 5 5 vollstandig neubearbeitete Auflage ed Berlin Heidelberg p 420 ISBN 978 3 642 58388 9 OCLC 913646782 a href Template Cite book html title Template Cite book cite book a CS1 maint location missing publisher link Phenicarbazid GESTIS Stoffdatenbank Retrieved 2022 10 18 1 Phenylsemicarbazide Sigma Aldrich nbsp This analgesic related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Phenicarbazide amp oldid 1119203976, wikipedia, wiki, book, books, library,