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Wikipedia

PPP2R2D

PP2A subunit B isoform delta also known as serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform is a protein that in humans is encoded by the PPP2R2D gene.[5] It is a regulatory subunit of the heterotrimeric protein phosphatase 2 enzyme.

PPP2R2D
Identifiers
AliasesPPP2R2D, MDS026, protein phosphatase 2 regulatory subunit Bdelta, B55delta, B55D
External IDsOMIM: 613992 MGI: 1289252 HomoloGene: 81915 GeneCards: PPP2R2D
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001003656
NM_001291310
NM_018461

NM_026391
NM_001347618

RefSeq (protein)

NP_001278239
NP_060931

NP_001334547
NP_080667

Location (UCSC)Chr 10: 131.9 – 131.96 MbChr 7: 138.85 – 138.88 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References edit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000175470 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000041769 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Protein phosphatase 2 regulatory subunit Bdelta".

Further reading edit

  • Batut J, Schmierer B, Cao J, Raftery LA, Hill CS, Howell M (September 2008). "Two highly related regulatory subunits of PP2A exert opposite effects on TGF-beta/Activin/Nodal signalling". Development. 135 (17): 2927–37. doi:10.1242/dev.020842. PMC 4940033. PMID 18697906.
  • Chen HF, Lin LN, Chen YX, Wan JX, Luo J, Zhang CZ, Li XJ, Hu YM, Mai JR, Chen W, Lin ZN, Lin YC (2012). "Identification and functional analysis of variant haplotypes in the 5'-flanking region of protein phosphatase 2A-Bδ gene". PLOS ONE. 7 (4): e35524. Bibcode:2012PLoSO...735524C. doi:10.1371/journal.pone.0035524. PMC 3335092. PMID 22539979.

ppp2r2d, pp2a, subunit, isoform, delta, also, known, serine, threonine, protein, phosphatase, regulatory, subunit, delta, isoform, protein, that, humans, encoded, gene, regulatory, subunit, heterotrimeric, protein, phosphatase, enzyme, identifiersaliases, mds0. PP2A subunit B isoform delta also known as serine threonine protein phosphatase 2A 55 kDa regulatory subunit B delta isoform is a protein that in humans is encoded by the PPP2R2D gene 5 It is a regulatory subunit of the heterotrimeric protein phosphatase 2 enzyme PPP2R2DIdentifiersAliasesPPP2R2D MDS026 protein phosphatase 2 regulatory subunit Bdelta B55delta B55DExternal IDsOMIM 613992 MGI 1289252 HomoloGene 81915 GeneCards PPP2R2DGene location Human Chr Chromosome 10 human 1 Band10q26 3Start131 901 008 bp 1 End131 959 834 bp 1 Gene location Mouse Chr Chromosome 7 mouse 2 Band7 F4 7 82 95 cMStart138 846 079 bp 2 End138 883 057 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed inbody of pancreascerebellar hemisphereleft adrenal glandganglionic eminenceanterior pituitaryprefrontal cortexAchilles tendonBrodmann area 23gastrocnemius muscleleft ventricleTop expressed ininternal carotid arteryfacial motor nucleusexternal carotid arteryseminiferous tubuleprimitive streakright ventriclespermatidbrown adipose tissuemotor neuronmedial ganglionic eminenceMore reference expression dataBioGPSn aGene ontologyMolecular functionprotein serine threonine phosphatase activity protein binding protein phosphatase regulator activityCellular componentcytoplasm protein phosphatase type 2A complex cytosolBiological processcell division cell cycle exit from mitosis peptidyl serine dephosphorylation mitotic cell cycle developmental process regulation of phosphoprotein phosphatase activitySources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez5584452432EnsemblENSG00000175470ENSMUSG00000041769UniProtQ66LE6Q925E7RefSeq mRNA NM 001003656NM 001291310NM 018461NM 026391NM 001347618RefSeq protein NP 001278239NP 060931NP 001334547NP 080667Location UCSC Chr 10 131 9 131 96 MbChr 7 138 85 138 88 MbPubMed search 3 4 WikidataView Edit HumanView Edit MouseReferences edit a b c GRCh38 Ensembl release 89 ENSG00000175470 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000041769 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Entrez Gene Protein phosphatase 2 regulatory subunit Bdelta Further reading editBatut J Schmierer B Cao J Raftery LA Hill CS Howell M September 2008 Two highly related regulatory subunits of PP2A exert opposite effects on TGF beta Activin Nodal signalling Development 135 17 2927 37 doi 10 1242 dev 020842 PMC 4940033 PMID 18697906 Chen HF Lin LN Chen YX Wan JX Luo J Zhang CZ Li XJ Hu YM Mai JR Chen W Lin ZN Lin YC 2012 Identification and functional analysis of variant haplotypes in the 5 flanking region of protein phosphatase 2A Bd gene PLOS ONE 7 4 e35524 Bibcode 2012PLoSO 735524C doi 10 1371 journal pone 0035524 PMC 3335092 PMID 22539979 nbsp This article on a gene on human chromosome 10 is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title PPP2R2D amp oldid 1116601659, wikipedia, wiki, book, books, library,

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