^ abcGRCh38: Ensembl release 89: ENSG00000052126 - Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000030231 - Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Nagase T, Kikuno R, Hattori A, Kondo Y, Okumura K, Ohara O (Feb 2001). "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (6): 347–55. doi:10.1093/dnares/7.6.347. PMID 11214970.
^Dowler S, Currie RA, Campbell DG, Deak M, Kular G, Downes CP, Alessi DR (Jan 2001). "Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities". Biochem J. 351 (Pt 1): 19–31. doi:10.1042/0264-6021:3510019. PMC1221362. PMID 11001876.
^"Entrez Gene: PLEKHA5 pleckstrin homology domain containing, family A member 5".
Further readingEdit
Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC442147. PMID 15231747.
Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–50. doi:10.1016/j.cub.2004.07.051. PMID 15324660.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC528928. PMID 15489334.
Zhang Y, Wolf-Yadlin A, Ross PL, et al. (2005). "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules". Mol. Cell. Proteomics. 4 (9): 1240–50. doi:10.1074/mcp.M500089-MCP200. PMID 15951569.
Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
External linksEdit
Overview of all the structural information available in the PDB for UniProt: P00698 (Pleckstrin homology domain-containing family A member 5) at the PDBe-KB.
This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by expanding it.
plekha5, pleckstrin, homology, domain, containing, family, member, protein, that, humans, encoded, gene, available, structurespdbhuman, uniprot, search, pdbe, rcsblist, codes2dkpidentifiersaliases, pepp, pepp2, pleckstrin, homology, domain, containing, a5exter. Pleckstrin homology domain containing family A member 5 is a protein that in humans is encoded by the PLEKHA5 gene 5 6 7 PLEKHA5Available structuresPDBHuman UniProt search PDBe RCSBList of PDB id codes2DKPIdentifiersAliasesPLEKHA5 PEPP 2 PEPP2 pleckstrin homology domain containing A5External IDsOMIM 607770 MGI 1923802 HomoloGene 10377 GeneCards PLEKHA5Gene location Human Chr Chromosome 12 human 1 Band12p12 3Start19 129 752 bp 1 End19 376 400 bp 1 Gene location Mouse Chr Chromosome 6 mouse 2 Band6 6 G2Start140 369 780 bp 2 End140 542 836 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed inbronchial epithelial cellendometriumcaput epididymisrenal medullacorpus epididymisright adrenal glandleft adrenal glandBrodmann area 23adrenal cortexseminal vesiculaTop expressed inspermatocytesuperior frontal gyrusolfactory tuberclecerebellar cortexsecondary oocyteolfactory bulbspermatidlipinferior ganglion of glossopharyngeal nervecerebellar vermisMore reference expression dataBioGPSMore reference expression dataGene ontologyMolecular functionphosphatidylinositol 4 phosphate binding phosphatidylinositol 5 phosphate binding protein binding phosphatidylinositol 3 phosphate binding phosphatidylinositol 3 5 bisphosphate bindingCellular componentmembrane nucleoplasm cytoplasm cytosol postsynaptic density glutamatergic synapseBiological processreproductive system development biological processSources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez54477109135EnsemblENSG00000052126ENSMUSG00000030231UniProtQ9HAU0n aRefSeq mRNA NM 001143821NM 001190860NM 001256470NM 001256787NM 019012NM 144920RefSeq protein NP 001137293NP 001177789NP 001243399NP 001243716NP 061885NP 001137293 2n aLocation UCSC Chr 12 19 13 19 38 MbChr 6 140 37 140 54 MbPubMed search 3 4 WikidataView Edit HumanView Edit MouseReferences Edit a b c GRCh38 Ensembl release 89 ENSG00000052126 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000030231 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Nagase T Kikuno R Hattori A Kondo Y Okumura K Ohara O Feb 2001 Prediction of the coding sequences of unidentified human genes XIX The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro DNA Res 7 6 347 55 doi 10 1093 dnares 7 6 347 PMID 11214970 Dowler S Currie RA Campbell DG Deak M Kular G Downes CP Alessi DR Jan 2001 Identification of pleckstrin homology domain containing proteins with novel phosphoinositide binding specificities Biochem J 351 Pt 1 19 31 doi 10 1042 0264 6021 3510019 PMC 1221362 PMID 11001876 Entrez Gene PLEKHA5 pleckstrin homology domain containing family A member 5 Further reading EditNakajima D Okazaki N Yamakawa H et al 2003 Construction of expression ready cDNA clones for KIAA genes manual curation of 330 KIAA cDNA clones DNA Res 9 3 99 106 doi 10 1093 dnares 9 3 99 PMID 12168954 Strausberg RL Feingold EA Grouse LH et al 2003 Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 99 26 16899 903 Bibcode 2002PNAS 9916899M doi 10 1073 pnas 242603899 PMC 139241 PMID 12477932 Ota T Suzuki Y Nishikawa T et al 2004 Complete sequencing and characterization of 21 243 full length human cDNAs Nat Genet 36 1 40 5 doi 10 1038 ng1285 PMID 14702039 Lehner B Sanderson CM 2004 A protein interaction framework for human mRNA degradation Genome Res 14 7 1315 23 doi 10 1101 gr 2122004 PMC 442147 PMID 15231747 Jin J Smith FD Stark C et al 2004 Proteomic functional and domain based analysis of in vivo 14 3 3 binding proteins involved in cytoskeletal regulation and cellular organization Curr Biol 14 16 1436 50 doi 10 1016 j cub 2004 07 051 PMID 15324660 Gerhard DS Wagner L Feingold EA et al 2004 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 10B 2121 7 doi 10 1101 gr 2596504 PMC 528928 PMID 15489334 Zhang Y Wolf Yadlin A Ross PL et al 2005 Time resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules Mol Cell Proteomics 4 9 1240 50 doi 10 1074 mcp M500089 MCP200 PMID 15951569 Lim J Hao T Shaw C et al 2006 A protein protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration Cell 125 4 801 14 doi 10 1016 j cell 2006 03 032 PMID 16713569 Beausoleil SA Villen J Gerber SA et al 2006 A probability based approach for high throughput protein phosphorylation analysis and site localization Nat Biotechnol 24 10 1285 92 doi 10 1038 nbt1240 PMID 16964243 S2CID 14294292 Olsen JV Blagoev B Gnad F et al 2006 Global in vivo and site specific phosphorylation dynamics in signaling networks Cell 127 3 635 48 doi 10 1016 j cell 2006 09 026 PMID 17081983 External links EditOverview of all the structural information available in the PDB for UniProt P00698 Pleckstrin homology domain containing family A member 5 at the PDBe KB This article on a gene on human chromosome 12 is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title PLEKHA5 amp oldid 1142723538, wikipedia, wiki, book, books, library,
