^ abIvanova D, Deneva V, Nedeltcheva D, Kamounah FS, Gergov G, Hansen PE, Kawauchi S, Antonov L (March 2015). "Tautomeric transformations of piroxicam in solution: a combined experimental and theoretical study". RSC Advances. England, UK: Royal Society of Chemistry. 5 (40): 31852–31860. Bibcode:2015RSCAd...531852I. doi:10.1039/c5ra03653d.
^Mutschler, Ernst; Gerd Geisslinger; Heyo K. Kroemer; Monika Schäfer-Korting (2001). Mutschler Arzneimittelwirkungen: Lehrbuch der Pharmakologie und Toxikologie ; mit einführenden Kapiteln in die Anatomie, Physiologie und Pathophysiologie [Mutster medicine effects: Textbook of pharmacology and toxicology; with introductory chapters in anatomy, physiology and pathophysiology] (in German) (8 ed.). Stuttgart, Germany: Wissenschaftliche Verlagsgesellschaft. p. 233. ISBN3-8047-1763-2. OCLC 48723029. OL 12928661M.
^Banerjee R, Chakraborty H, Sarkar M (April 2003). "Photophysical studies of oxicam group of NSAIDs: piroxicam, meloxicam and tenoxicam". Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. Elsevier. 59 (6): 1213–22. Bibcode:2003AcSpA..59.1213B. doi:10.1016/S1386-1425(02)00300-1. PMID 12659890.
oxicam, class, steroidal, anti, inflammatory, drugs, nsaids, meaning, that, they, have, anti, inflammatory, analgesic, antipyretic, therapeutic, effects, bind, closely, plasma, proteins, most, oxicams, unselective, inhibitors, cyclooxygenase, enzymes, exceptio. Oxicam is a class of non steroidal anti inflammatory drugs NSAIDs 2 meaning that they have anti inflammatory analgesic and antipyretic therapeutic effects Oxicams bind closely to plasma proteins 1 Most oxicams are unselective inhibitors of the cyclooxygenase COX enzymes The exception is meloxicam with a slight 10 1 preference for COX 2 which however is only clinically relevant at low doses 3 Piroxicam the most popular drug of the oxicam class 1 The most popular drug of the oxicam class is piroxicam 1 Other examples include ampiroxicam droxicam pivoxicam tenoxicam lornoxicam 1 and meloxicam Isoxicam has been suspended as a result of fatal skin reactions 1 Chemistry editThe physico chemical characteristics of these molecules vary greatly depending upon the environment 4 In contrast to most other NSAIDs oxicams are not carboxylic acids They are tautomeric and can exist as a number of tautomers keto enol tautomerism here exemplified by piroxicam 2 nbsp Side effects editThis section has no medical references for verification or relies exclusively on non medical sources Please review the contents of the section and add the appropriate references if you can Unsourced or poorly sourced material may be challenged and removed February 2022 Learn how and when to remove this template message nbsp The oxicams are associated with drug related erythema multiforme EM Stevens Johnson syndrome and toxic epidermal necrolysis TEN This association is one of the reasons oxicams are not regularly prescribed References edit a b c d e Olkkola KT Brunetto AV Mattila MJ February 1994 Pharmacokinetics of oxicam nonsteroidal anti inflammatory agents Clinical Pharmacokinetics 26 2 107 20 doi 10 2165 00003088 199426020 00004 PMID 8162655 S2CID 13300943 a b Ivanova D Deneva V Nedeltcheva D Kamounah FS Gergov G Hansen PE Kawauchi S Antonov L March 2015 Tautomeric transformations of piroxicam in solution a combined experimental and theoretical study RSC Advances England UK Royal Society of Chemistry 5 40 31852 31860 Bibcode 2015RSCAd 531852I doi 10 1039 c5ra03653d Mutschler Ernst Gerd Geisslinger Heyo K Kroemer Monika Schafer Korting 2001 Mutschler Arzneimittelwirkungen Lehrbuch der Pharmakologie und Toxikologie mit einfuhrenden Kapiteln in die Anatomie Physiologie und Pathophysiologie Mutster medicine effects Textbook of pharmacology and toxicology with introductory chapters in anatomy physiology and pathophysiology in German 8 ed Stuttgart Germany Wissenschaftliche Verlagsgesellschaft p 233 ISBN 3 8047 1763 2 OCLC 48723029 OL 12928661M Banerjee R Chakraborty H Sarkar M April 2003 Photophysical studies of oxicam group of NSAIDs piroxicam meloxicam and tenoxicam Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy Elsevier 59 6 1213 22 Bibcode 2003AcSpA 59 1213B doi 10 1016 S1386 1425 02 00300 1 PMID 12659890 nbsp This drug article relating to the musculoskeletal system is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Oxicam amp oldid 1161412910, wikipedia, wiki, book, books, library,
