An ovotestis is a gonad with both testicular and ovarian aspects.[1][2] In humans, ovotestes are an infrequent anatomical variation associated with gonadal dysgenesis.[3] The only mammals where ovotestes are not symptomatic of an intersex variation are moles, wherein females possess ovotestes along with a masculinized clitoris. These ovotestes in nonpregnant female moles secrete eight times as much testosterone as the ovotestes of pregnant moles.[4] In invertebrates that are normally hermaphroditic, such as most gastropods (snails and slugs) in the clade Eupulmonata, an ovotestis is a common feature of the reproductive anatomy.
In mice, ovotestes are structured such that the central region is testicular tissue while the poles both contain ovarian tissue. Experiments involving the SOX9 gene, which is initiated by the SRY region of the Y chromosome, have shown the gene's requirement for testicular differentiation from the presence of ovotestis formation within XX Sox9 trangenic mice. (6) Ovotestis within B6-XYPOS mice allow for gonadal development research within the same tissue to take place in ways previously unavailable.[5][6]
^"eMedicine - Ovotestis : Article by Gail F Whitman-Elia, MD". Retrieved 2008-01-02.
^"ovo-testes (formerly called "true hermaphroditism")". Intersex Society of North America. Retrieved 2007-12-08.
^Salas-Cortés L, Jaubert F, Nihoul-Feketé C, Brauner R, Rosemblatt M, Fellous M (2000). "SRY protein is expressed in ovotestis and streak gonads from human sex-reversal". Cytogenet. Cell Genet. 91 (1–4): 212–6. doi:10.1159/000056847. PMID 11173859. S2CID 32843904.
^Whitworth, Deanne; Licht, Paul; Racey, Paul; Glickman, Stephen (1999-02-01). "Testis-Like Steroidogenesis in the Ovotestis of the European Mole, Talpa europaea". Biology of Reproduction. 60 (2): 413–418. doi:10.1095/biolreprod60.2.413. PMID 9916009.
^Gregoire EP et al. (2011). “Transient development of ovotestes in XX Sox9 transgenic mice.” Dev Biol. 394(1):65-77
^Wilhelm D, Washburn LL, Truong V, Fellous M, Eicher EM, Koopman P. Antagonism of the testis- and ovary-determining pathways during ovotestis development in mice. Mechanisms of Development. 2009;126(5-6):324-336.
^Páll-Gergely, Barna (2008). "A Stylommatophora csigák ivarszervrendszerének magyar nyelvű nevezéktana" (PDF). Malacological Newsletter (in Hungarian). 26: 37–42.
^Chase R, Antkowiak T, Geoffroy E, Weatherill D (2004). "Why the ovotestis of Helix aspersa is innervated". Acta Biol. Hung. 55 (1–4): 239–49. doi:10.1556/ABiol.55.2004.1-4.29. PMID 15270240.
^""А не догадается ли она, что со мной что-то "не так"?": Интерсекс-люди о своём сексуальном опыте". Wonderzine. 2021-02-19. Retrieved 2021-03-21.
December 18, 2023
ovotestis, ovotestis, gonad, with, both, testicular, ovarian, aspects, humans, ovotestes, infrequent, anatomical, variation, associated, with, gonadal, dysgenesis, only, mammals, where, ovotestes, symptomatic, intersex, variation, moles, wherein, females, poss. An ovotestis is a gonad with both testicular and ovarian aspects 1 2 In humans ovotestes are an infrequent anatomical variation associated with gonadal dysgenesis 3 The only mammals where ovotestes are not symptomatic of an intersex variation are moles wherein females possess ovotestes along with a masculinized clitoris These ovotestes in nonpregnant female moles secrete eight times as much testosterone as the ovotestes of pregnant moles 4 In invertebrates that are normally hermaphroditic such as most gastropods snails and slugs in the clade Eupulmonata an ovotestis is a common feature of the reproductive anatomy In mice ovotestes are structured such that the central region is testicular tissue while the poles both contain ovarian tissue Experiments involving the SOX9 gene which is initiated by the SRY region of the Y chromosome have shown the gene s requirement for testicular differentiation from the presence of ovotestis formation within XX Sox9 trangenic mice 6 Ovotestis within B6 XYPOS mice allow for gonadal development research within the same tissue to take place in ways previously unavailable 5 6 Contents 1 In gastropods 2 People with Ovotestis 3 See also 4 ReferencesIn gastropods edit nbsp The ovotestis of the freshwater snail Biomphalaria glabrata The area around the ovotestis is the hepatopancreas 10 magnification An ovotestis or hermaphroditic gland Latin glandula hermaphroditica 7 is found as normal anatomical feature in the reproductive system of some gastropods including such species as the land snail Cornu aspersum 8 People with Ovotestis editCheryl Chase activist Anton Krzyzanowski 9 See also editIntersex True hermaphroditismReferences edit eMedicine Ovotestis Article by Gail F Whitman Elia MD Retrieved 2008 01 02 ovo testes formerly called true hermaphroditism Intersex Society of North America Retrieved 2007 12 08 Salas Cortes L Jaubert F Nihoul Fekete C Brauner R Rosemblatt M Fellous M 2000 SRY protein is expressed in ovotestis and streak gonads from human sex reversal Cytogenet Cell Genet 91 1 4 212 6 doi 10 1159 000056847 PMID 11173859 S2CID 32843904 Whitworth Deanne Licht Paul Racey Paul Glickman Stephen 1999 02 01 Testis Like Steroidogenesis in the Ovotestis of the European Mole Talpa europaea Biology of Reproduction 60 2 413 418 doi 10 1095 biolreprod60 2 413 PMID 9916009 Gregoire EP et al 2011 Transient development of ovotestes in XX Sox9 transgenic mice Dev Biol 394 1 65 77 Wilhelm D Washburn LL Truong V Fellous M Eicher EM Koopman P Antagonism of the testis and ovary determining pathways during ovotestis development in mice Mechanisms of Development 2009 126 5 6 324 336 Pall Gergely Barna 2008 A Stylommatophora csigak ivarszervrendszerenek magyar nyelvu nevezektana PDF Malacological Newsletter in Hungarian 26 37 42 Chase R Antkowiak T Geoffroy E Weatherill D 2004 Why the ovotestis of Helix aspersa is innervated Acta Biol Hung 55 1 4 239 49 doi 10 1556 ABiol 55 2004 1 4 29 PMID 15270240 A ne dogadaetsya li ona chto so mnoj chto to ne tak Interseks lyudi o svoyom seksualnom opyte Wonderzine 2021 02 19 Retrieved 2021 03 21 Retrieved from https en wikipedia org w index php title Ovotestis amp oldid 1167476366, wikipedia, wiki, book, books, library,
