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Wikipedia

Oral administration

Oral administration is a route of administration whereby a substance is taken through the mouth, swallowed, and then processed via the digestive system. This is a common route of administration for many medications.

Oral administration
Oral administration of a tablet
Other namesBy mouth, per os (PO)
[edit on Wikidata]
A health professional demonstrates how to offer oral medication to a dummy.
Oral administration of a liquid

Oral administration can be easier and less painful than other routes of administration, such as injection. However, the onset of action is relatively low, and the effectiveness is reduced if it is not absorbed properly in the digestive system, or if it is broken down by digestive enzymes before it can reach the bloodstream. Some medications may cause gastrointestinal side effects, such as nausea or vomiting, when taken orally. Oral administration can also only be applied to conscious patients, and patients able to swallow.[1]

Terminology edit

Per os (/ˌpɜːrˈs/; P.O.) is an adverbial phrase meaning literally from Latin "through the mouth" or "by mouth". The expression is used in medicine to describe a treatment that is taken orally (but not used in the mouth such as, for example, caries prophylaxis).[2] The abbreviation P.O. is often used on medical prescriptions.

Scope edit

Enteral administration includes:

  • Buccal, dissolved inside the cheek
  • Sublabial, dissolved under the lip
  • Sublingual administration (SL), dissolved under the tongue, but due to rapid absorption many consider SL a parenteral route
  • Oral (PO), swallowed tablet, capsule or liquid

Enteral medications come in various forms, including[3] oral solid dosage (OSD) forms:[4]

  • Tablets to swallow, chew or dissolve in water or under the tongue
  • Capsules and chewable capsules (with a coating that dissolves in the stomach or bowel to release the medication there)
  • Time-release or sustained-release tablets and capsules (which release the medication gradually)
  • Powders or granules

and oral liquid dosage forms:[5]

  • Teas
  • Drops
  • Liquid medications or syrups

Facilitating methods edit

Concomitant ingestion of water facilitates in swallowing tablets and capsules.[6] If the substance has disagreeable taste, addition of a flavor may facilitate ingestion.[6] Substances that are harmful to the teeth are preferably given through a straw.[6]

See also edit

References edit

  1. ^ "Oral Administration of Drugs: Advantages and Disadvantages". Retrieved December 8, 2022.
  2. ^ Hunnius Pharmazeutisches Wörterbuch (in German) (8th ed.). Berlin: Walter de Gruyter. 1998. p. 1048. ISBN 3-11-015793-4.
  3. ^ Institute for Quality and Efficiency in Health Care. "Oral medications". Informed Health Online. Institute for Quality and Efficiency in Health Care. Retrieved 22 June 2013.
  4. ^ Jacobs, Terry; Signore, Andrew A. (2016-08-19). Good Design Practices for GMP Pharmaceutical Facilities. CRC Press. ISBN 978-1-4822-5891-2.
  5. ^ McCabe-Sellers, Beverly; Frankel, Eric H.; Wolfe, Jonathan J. (2003-04-29). Handbook of Food-Drug Interactions. CRC Press. ISBN 978-0-203-49024-2.
  6. ^ a b c TheFreeDictionary > oral administration of medication Citing: Mosby's Medical Dictionary, 8th edition. 2009

oral, administration, route, administration, whereby, substance, taken, through, mouth, swallowed, then, processed, digestive, system, this, common, route, administration, many, medications, tabletother, namesby, mouth, edit, wikidata, health, professional, de. Oral administration is a route of administration whereby a substance is taken through the mouth swallowed and then processed via the digestive system This is a common route of administration for many medications Oral administrationOral administration of a tabletOther namesBy mouth per os PO edit on Wikidata A health professional demonstrates how to offer oral medication to a dummy Oral administration of a liquidOral administration can be easier and less painful than other routes of administration such as injection However the onset of action is relatively low and the effectiveness is reduced if it is not absorbed properly in the digestive system or if it is broken down by digestive enzymes before it can reach the bloodstream Some medications may cause gastrointestinal side effects such as nausea or vomiting when taken orally Oral administration can also only be applied to conscious patients and patients able to swallow 1 Contents 1 Terminology 2 Scope 3 Facilitating methods 4 See also 5 ReferencesTerminology editPer os ˌ p ɜːr ˈ oʊ s P O is an adverbial phrase meaning literally from Latin through the mouth or by mouth The expression is used in medicine to describe a treatment that is taken orally but not used in the mouth such as for example caries prophylaxis 2 The abbreviation P O is often used on medical prescriptions Scope editEnteral administration includes Buccal dissolved inside the cheek Sublabial dissolved under the lip Sublingual administration SL dissolved under the tongue but due to rapid absorption many consider SL a parenteral route Oral PO swallowed tablet capsule or liquidEnteral medications come in various forms including 3 oral solid dosage OSD forms 4 Tablets to swallow chew or dissolve in water or under the tongue Capsules and chewable capsules with a coating that dissolves in the stomach or bowel to release the medication there Time release or sustained release tablets and capsules which release the medication gradually Powders or granulesand oral liquid dosage forms 5 Teas Drops Liquid medications or syrupsFacilitating methods editConcomitant ingestion of water facilitates in swallowing tablets and capsules 6 If the substance has disagreeable taste addition of a flavor may facilitate ingestion 6 Substances that are harmful to the teeth are preferably given through a straw 6 See also editNothing by mouth List of abbreviations used in medical prescriptions List of Latin phrases Medical prescription Thin film drug deliveryReferences edit Oral Administration of Drugs Advantages and Disadvantages Retrieved December 8 2022 Hunnius Pharmazeutisches Worterbuch in German 8th ed Berlin Walter de Gruyter 1998 p 1048 ISBN 3 11 015793 4 Institute for Quality and Efficiency in Health Care Oral medications Informed Health Online Institute for Quality and Efficiency in Health Care Retrieved 22 June 2013 Jacobs Terry Signore Andrew A 2016 08 19 Good Design Practices for GMP Pharmaceutical Facilities CRC Press ISBN 978 1 4822 5891 2 McCabe Sellers Beverly Frankel Eric H Wolfe Jonathan J 2003 04 29 Handbook of Food Drug Interactions CRC Press ISBN 978 0 203 49024 2 a b c TheFreeDictionary gt oral administration of medication Citing Mosby s Medical Dictionary 8th edition 2009 Retrieved from https en wikipedia org w index php title Oral administration amp oldid 1211950358, wikipedia, wiki, book, books, library,

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