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Wikipedia

Nucleoporin 188

Nucleoporin 188 (Nup188) is a protein that in humans is encoded by the NUP188 gene.[5][6]

NUP188
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesNUP188, KIAA0169, hNup188, nucleoporin 188kDa, nucleoporin 188, SANDSTEF
External IDsOMIM: 615587 MGI: 2446190 HomoloGene: 45683 GeneCards: NUP188
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015354

NM_198304

RefSeq (protein)

NP_056169

NP_938046

Location (UCSC)Chr 9: 128.95 – 129.01 MbChr 2: 30.18 – 30.23 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function edit

Transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP188 is part of one such subcomplex.[5]

References edit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000095319 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000052533 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: NUP188 nucleoporin 188kDa".
  6. ^ Miller BR, Powers M, Park M, Fischer W, Forbes DJ (October 2000). "Identification of a New Vertebrate Nucleoporin, Nup188, with the Use of a Novel Organelle Trap Assay". Mol. Biol. Cell. 11 (10): 3381–96. doi:10.1091/mbc.11.10.3381. PMC 15000. PMID 11029043.

External links edit

  • Overview of all the structural information available in the PDB for UniProt: Q5SRE5 (Human Nucleoporin NUP188 homolog (NUP188)) at the PDBe-KB.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


nucleoporin, nup188, protein, that, humans, encoded, nup188, gene, nup188available, structurespdbortholog, search, pdbe, rcsblist, codes5ijoidentifiersaliasesnup188, kiaa0169, hnup188, nucleoporin, 188kda, nucleoporin, sandstefexternal, idsomim, 615587, 244619. Nucleoporin 188 Nup188 is a protein that in humans is encoded by the NUP188 gene 5 6 NUP188Available structuresPDBOrtholog search PDBe RCSBList of PDB id codes5IJOIdentifiersAliasesNUP188 KIAA0169 hNup188 nucleoporin 188kDa nucleoporin 188 SANDSTEFExternal IDsOMIM 615587 MGI 2446190 HomoloGene 45683 GeneCards NUP188Gene location Human Chr Chromosome 9 human 1 Band9q34 11Start128 947 699 bp 1 End129 007 096 bp 1 Gene location Mouse Chr Chromosome 2 mouse 2 Band2 2 BStart30 176 409 bp 2 End30 234 278 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed incerebellar hemisphereanterior pituitarystromal cell of endometriumgastric mucosaright uterine tubeskin of abdomenleft lobe of thyroid glandganglionic eminenceleft uterine tuberight lobe of thyroid glandTop expressed inspermatocytespermatidseminiferous tubulemaxillary prominencesomitethymussecondary oocyteyolk sacmolarinternal carotid arteryMore reference expression dataBioGPSn aGene ontologyMolecular functionstructural constituent of nuclear poreCellular componentnuclear pore nucleus nuclear pore inner ring nuclear envelope membrane host cellBiological processmitotic nuclear membrane disassembly viral transcription protein import into nucleus viral process RNA export from nucleus protein sumoylation protein transport mRNA transport regulation of cellular response to heat intracellular transport of virus glomerular visceral epithelial cell migration mRNA export from nucleus tRNA export from nucleus regulation of gene silencing by miRNA regulation of glycolytic process transportSources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez23511227699EnsemblENSG00000095319ENSMUSG00000052533UniProtQ5SRE5Q6ZQH8RefSeq mRNA NM 015354NM 198304RefSeq protein NP 056169NP 938046Location UCSC Chr 9 128 95 129 01 MbChr 2 30 18 30 23 MbPubMed search 3 4 WikidataView Edit HumanView Edit MouseFunction editTransport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes NPCs embedded in the nuclear envelope NPCs are composed of subcomplexes and NUP188 is part of one such subcomplex 5 References edit a b c GRCh38 Ensembl release 89 ENSG00000095319 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000052533 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine a b Entrez Gene NUP188 nucleoporin 188kDa Miller BR Powers M Park M Fischer W Forbes DJ October 2000 Identification of a New Vertebrate Nucleoporin Nup188 with the Use of a Novel Organelle Trap Assay Mol Biol Cell 11 10 3381 96 doi 10 1091 mbc 11 10 3381 PMC 15000 PMID 11029043 External links editOverview of all the structural information available in the PDB for UniProt Q5SRE5 Human Nucleoporin NUP188 homolog NUP188 at the PDBe KB This article incorporates text from the United States National Library of Medicine which is in the public domain nbsp This article on a gene on human chromosome 9 is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Nucleoporin 188 amp oldid 1079674425, wikipedia, wiki, book, books, library,

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