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Wikipedia

NME1

December 14, 2023

Nucleoside diphosphate kinase A is an enzyme that in humans is encoded by the NME1 gene.[5] It is thought to be a metastasis suppressor.

NME1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesNME1, AWD, GAAD, NB, NBS, NDKA, NDPK-A, NDPKA, NM23, NM23-H1, NME/NM23 nucleoside diphosphate kinase 1
External IDsOMIM: 156490 MGI: 97355 HomoloGene: 128514 GeneCards: NME1
Orthologs
SpeciesHumanMouse
Entrez

4830

18102

Ensembl

ENSG00000239672

ENSMUSG00000037601

UniProt

P15531

P15532

RefSeq (mRNA)

NM_198175
NM_000269

NM_008704
NM_001378854

RefSeq (protein)

NP_000260
NP_937818

NP_032730
NP_001365783

Location (UCSC)Chr 17: 51.15 – 51.16 MbChr 11: 93.85 – 93.86 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
For the radio station, see NME Radio.

Function edit

This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally occurring transcripts (NME1-NME2), which encodes a fusion protein consisting of sequence sharing identity with each individual gene product.[6]

A bioinformatics study published in 2023 suggested that the NME1 gene might have a prognostic role in neuroblastoma.[7]

Interactions edit

NME1 has been shown to interact with:

See also edit

References edit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000239672 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000037601 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Dooley S, Seib T, Engel M, Theisinger B, Janz H, Piontek K, Zang KD, Welter C (February 1994). "Isolation and characterization of the human genomic locus coding for the putative metastasis control gene nm23-H1". Hum. Genet. 93 (1): 63–6. doi:10.1007/bf00218915. PMID 8270257. S2CID 6373221.
  6. ^ "Entrez Gene: NME1 non-metastatic cells 1, protein (NM23A) expressed in".
  7. ^ Chicco, Davide; Sanavia, Tiziana; Jurman, Giuseppe (4 March 2023). "Signature literature review reveals AHCY, DPYSL3, and NME1 as the most recurrent prognostic genes for neuroblastoma". BioData Mining. 16 (1): 7. doi:10.1186/s13040-023-00325-1. eISSN 1756-0381. PMC 9985261. PMID 36870971.
  8. ^ Du J, Hannon GJ (December 2002). "The centrosomal kinase Aurora-A/STK15 interacts with a putative tumor suppressor NM23-H1". Nucleic Acids Res. 30 (24): 5465–75. doi:10.1093/nar/gkf678. PMC 140054. PMID 12490715.
  9. ^ Fournier HN, Dupé-Manet S, Bouvard D, Lacombe ML, Marie C, Block MR, Albiges-Rizo C (June 2002). "Integrin cytoplasmic domain-associated protein 1alpha (ICAP-1alpha ) interacts directly with the metastasis suppressor nm23-H2, and both proteins are targeted to newly formed cell adhesion sites upon integrin engagement". J. Biol. Chem. 277 (23): 20895–902. doi:10.1074/jbc.M200200200. PMID 11919189.
  10. ^ Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
  11. ^ Negroni A, Venturelli D, Tanno B, Amendola R, Ransac S, Cesi V, Calabretta B, Raschellà G (September 2000). "Neuroblastoma specific effects of DR-nm23 and its mutant forms on differentiation and apoptosis". Cell Death Differ. 7 (9): 843–50. doi:10.1038/sj.cdd.4400720. PMID 11042679.
  12. ^ Chakravarti D, Hong R (March 2003). "SET-ting the stage for life and death". Cell. 112 (5): 589–91. doi:10.1016/s0092-8674(03)00151-x. PMID 12628178. S2CID 16423565.
  13. ^ a b Paravicini G, Steinmayr M, André E, Becker-André M (October 1996). "The metastasis suppressor candidate nucleotide diphosphate kinase NM23 specifically interacts with members of the ROR/RZR nuclear orphan receptor subfamily". Biochem. Biophys. Res. Commun. 227 (1): 82–7. doi:10.1006/bbrc.1996.1471. PMID 8858107.
  14. ^ Nosaka K, Kawahara M, Masuda M, Satomi Y, Nishino H (February 1998). "Association of nucleoside diphosphate kinase nm23-H2 with human telomeres". Biochem. Biophys. Res. Commun. 243 (2): 342–8. doi:10.1006/bbrc.1997.8097. PMID 9480811.

Further reading edit

  • Freije JM, MacDonald NJ, Steeg PS (1998). "Nm23 and tumour metastasis: basic and translational advances". Biochem. Soc. Symp. 63: 261–71. PMID 9513729.
  • Roymans D, Willems R, Van Blockstaele DR, Slegers H (2002). "Nucleoside diphosphate kinase (NDPK/NM23) and the waltz with multiple partners: possible consequences in tumor metastasis". Clin. Exp. Metastasis. 19 (6): 465–76. doi:10.1023/A:1020396722860. PMID 12405283. S2CID 21876557.
  • Tee YT, Chen GD, Lin LY, Ko JL, Wang PH (2006). "Nm23-H1: a metastasis-associated gene". Taiwan J Obstet Gynecol. 45 (2): 107–13. doi:10.1016/S1028-4559(09)60206-0. PMID 17197349.
  • Gilles AM, Presecan E, Vonica A, Lascu I (1991). "Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme". J. Biol. Chem. 266 (14): 8784–9. doi:10.1016/S0021-9258(18)31515-1. PMID 1851158.
  • Leone A, McBride OW, Weston A, Wang MG, Anglard P, Cropp CS, Goepel JR, Lidereau R, Callahan R, Linehan WM (1991). "Somatic allelic deletion of nm23 in human cancer". Cancer Res. 51 (9): 2490–3. PMID 2015608.
  • Hailat N, Keim DR, Melhem RF, Zhu XX, Eckerskorn C, Brodeur GM, Reynolds CP, Seeger RC, Lottspeich F, Strahler JR (1991). "High levels of p19/nm23 protein in neuroblastoma are associated with advanced stage disease and with N-myc gene amplification". J. Clin. Invest. 88 (1): 341–5. doi:10.1172/JCI115299. PMC 296039. PMID 2056128.
  • Rosengard AM, Krutzsch HC, Shearn A, Biggs JR, Barker E, Margulies IM, King CR, Liotta LA, Steeg PS (1989). "Reduced Nm23/Awd protein in tumour metastasis and aberrant Drosophila development". Nature. 342 (6246): 177–80. Bibcode:1989Natur.342..177R. doi:10.1038/342177a0. PMID 2509941. S2CID 4340066.
  • Wang L, Patel U, Ghosh L, Chen HC, Banerjee S (1993). "Mutation in the nm23 gene is associated with metastasis in colorectal cancer". Cancer Res. 53 (4): 717–20. PMID 7916650.
  • Chang CL, Zhu XX, Thoraval DH, Ungar D, Rawwas J, Hora N, Strahler JR, Hanash SM, Radany E (1994). "Nm23-H1 mutation in neuroblastoma" (PDF). Nature. 370 (6488): 335–6. Bibcode:1994Natur.370..335C. doi:10.1038/370335a0. hdl:2027.42/62612. PMID 8047138. S2CID 4356706.
  • MacDonald NJ, De la Rosa A, Benedict MA, Freije JM, Krutsch H, Steeg PS (1993). "A serine phosphorylation of Nm23, and not its nucleoside diphosphate kinase activity, correlates with suppression of tumor metastatic potential". J. Biol. Chem. 268 (34): 25780–9. doi:10.1016/S0021-9258(19)74458-5. PMID 8245015.
  • Postel EH, Berberich SJ, Flint SJ, Ferrone CA (1993). "Human c-myc transcription factor PuF identified as nm23-H2 nucleoside diphosphate kinase, a candidate suppressor of tumor metastasis". Science. 261 (5120): 478–80. Bibcode:1993Sci...261..478P. doi:10.1126/science.8392752. PMID 8392752.
  • Sudbrak R, Golla A, Hogan K, Powers P, Gregg R, Du Chesne I, Lehmann-Horn F, Deufel T (1993). (PDF). Hum. Mol. Genet. 2 (7): 857–62. doi:10.1093/hmg/2.7.857. PMID 8395939. S2CID 86750140. Archived from the original (PDF) on 2020-02-07.
  • MacDonald NJ, Freije JM, Stracke ML, Manrow RE, Steeg PS (1996). "Site-directed mutagenesis of nm23-H1. Mutation of proline 96 or serine 120 abrogates its motility inhibitory activity upon transfection into human breast carcinoma cells". J. Biol. Chem. 271 (41): 25107–16. doi:10.1074/jbc.271.41.25107. PMID 8810265.
  • Paravicini G, Steinmayr M, André E, Becker-André M (1996). "The metastasis suppressor candidate nucleotide diphosphate kinase NM23 specifically interacts with members of the ROR/RZR nuclear orphan receptor subfamily". Biochem. Biophys. Res. Commun. 227 (1): 82–7. doi:10.1006/bbrc.1996.1471. PMID 8858107.
  • Nosaka K, Kawahara M, Masuda M, Satomi Y, Nishino H (1998). "Association of nucleoside diphosphate kinase nm23-H2 with human telomeres". Biochem. Biophys. Res. Commun. 243 (2): 342–8. doi:10.1006/bbrc.1997.8097. PMID 9480811.
  • Schaertl S, Konrad M, Geeves MA (1998). "Substrate specificity of human nucleoside-diphosphate kinase revealed by transient kinetic analysis". J. Biol. Chem. 273 (10): 5662–9. doi:10.1074/jbc.273.10.5662. PMID 9488696.
  • Willems R, Van Bockstaele DR, Lardon F, Lenjou M, Nijs G, Snoeck HW, Berneman ZN, Slegers H (1998). "Decrease in nucleoside diphosphate kinase (NDPK/nm23) expression during hematopoietic maturation". J. Biol. Chem. 273 (22): 13663–8. doi:10.1074/jbc.273.22.13663. PMID 9593706.
  • Manda R, Kohno T, Matsuno Y, Takenoshita S, Kuwano H, Yokota J (1999). "Identification of genes (SPON2 and C20orf2) differentially expressed between cancerous and noncancerous lung cells by mRNA differential display". Genomics. 61 (1): 5–14. doi:10.1006/geno.1999.5939. PMID 10512675.
  • Chicco, Davide; Sanavia, Tiziana; Jurman, Giuseppe (4 March 2023). "Signature literature review reveals AHCY, DPYSL3, and NME1 as the most recurrent prognostic genes for neuroblastoma". BioData Mining. 16 (1): 7. doi:10.1186/s13040-023-00325-1. eISSN 1756-0381. PMC 9985261. PMID 36870971.

December 14, 2023
nme1, nucleoside, diphosphate, kinase, enzyme, that, humans, encoded, gene, thought, metastasis, suppressor, available, structurespdbortholog, search, pdbe, rcsblist, codes1jxv, 1ucn, 2hvd, 2hve, 3l7u, 4enoidentifiersaliases, gaad, ndka, ndpk, ndpka, nm23, nm2. Nucleoside diphosphate kinase A is an enzyme that in humans is encoded by the NME1 gene 5 It is thought to be a metastasis suppressor NME1Available structuresPDBOrtholog search PDBe RCSBList of PDB id codes1JXV 1UCN 2HVD 2HVE 3L7U 4ENOIdentifiersAliasesNME1 AWD GAAD NB NBS NDKA NDPK A NDPKA NM23 NM23 H1 NME NM23 nucleoside diphosphate kinase 1External IDsOMIM 156490 MGI 97355 HomoloGene 128514 GeneCards NME1Gene location Human Chr Chromosome 17 human 1 Band17q21 33Start51 153 559 bp 1 End51 162 428 bp 1 Gene location Mouse Chr Chromosome 11 mouse 2 Band11 11 DStart93 847 805 bp 2 End93 859 347 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed inprefrontal cortexhypothalamusBrodmann area 9superior frontal gyrusislet of Langerhansganglionic eminencehippocampus propercingulate gyrusappendixfrontal poleTop expressed inneural tubeproximal tubuleganglionic eminencemorulasuperior frontal gyrusyolk saclensbone marrowmesencephalonamygdalaMore reference expression dataBioGPSn aGene ontologyMolecular functiontransferase activity nucleotide binding deoxyribonuclease activity ribosomal small subunit binding GTP binding metal ion binding kinase activity protein binding identical protein binding ATP binding magnesium ion binding nucleoside diphosphate kinase activity RNA binding RNA polymerase II transcription regulatory region sequence specific DNA binding single stranded DNA binding intermediate filament binding enzyme binding protein kinase binding gamma tubulin bindingCellular componentruffle membrane extracellular exosome nucleus cytoplasm mitochondrial outer membrane centrosome cytosol intermediate filament membrane perinuclear region of cytoplasm mitochondrion myelin sheathBiological processUTP biosynthetic process regulation of apoptotic process cell differentiation nucleobase containing small molecule interconversion CTP biosynthetic process endocytosis phosphorylation positive regulation of epithelial cell proliferation nucleotide metabolic process nucleoside diphosphate phosphorylation nervous system development positive regulation of DNA binding GTP biosynthetic process negative regulation of cell population proliferation DNA metabolic process negative regulation of myeloid leukocyte differentiation negative regulation of gene expression positive regulation of neuron projection development response to amine hippocampus development response to testosterone response to cAMP cellular response to glucose stimulus cellular response to fatty acid lactation mammary gland developmentSources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez483018102EnsemblENSG00000239672ENSMUSG00000037601UniProtP15531P15532RefSeq mRNA NM 198175NM 000269NM 008704NM 001378854RefSeq protein NP 000260NP 937818NP 032730NP 001365783Location UCSC Chr 17 51 15 51 16 MbChr 11 93 85 93 86 MbPubMed search 3 4 WikidataView Edit HumanView Edit MouseFor the radio station see NME Radio Contents 1 Function 2 Interactions 3 See also 4 References 5 Further readingFunction editThis gene NME1 was identified because of its reduced mRNA transcript levels in highly metastatic cells Nucleoside diphosphate kinase NDK exists as a hexamer composed of A encoded by this gene and B encoded by NME2 isoforms Mutations in this gene have been identified in aggressive neuroblastomas Two transcript variants encoding different isoforms have been found for this gene Co transcription of this gene and the neighboring downstream gene NME2 generates naturally occurring transcripts NME1 NME2 which encodes a fusion protein consisting of sequence sharing identity with each individual gene product 6 A bioinformatics study published in 2023 suggested that the NME1 gene might have a prognostic role in neuroblastoma 7 Interactions editNME1 has been shown to interact with Aurora A kinase 8 CD29 9 NME3 10 11 Protein SET 12 RAR related orphan receptor alpha 13 RAR related orphan receptor beta 13 and TERF1 14 See also editNucleoside diphosphate kinaseReferences edit a b c GRCh38 Ensembl release 89 ENSG00000239672 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000037601 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Dooley S Seib T Engel M Theisinger B Janz H Piontek K Zang KD Welter C February 1994 Isolation and characterization of the human genomic locus coding for the putative metastasis control gene nm23 H1 Hum Genet 93 1 63 6 doi 10 1007 bf00218915 PMID 8270257 S2CID 6373221 Entrez Gene NME1 non metastatic cells 1 protein NM23A expressed in Chicco Davide Sanavia Tiziana Jurman Giuseppe 4 March 2023 Signature literature review reveals AHCY DPYSL3 and NME1 as the most recurrent prognostic genes for neuroblastoma BioData Mining 16 1 7 doi 10 1186 s13040 023 00325 1 eISSN 1756 0381 PMC 9985261 PMID 36870971 Du J Hannon GJ December 2002 The centrosomal kinase Aurora A STK15 interacts with a putative tumor suppressor NM23 H1 Nucleic Acids Res 30 24 5465 75 doi 10 1093 nar gkf678 PMC 140054 PMID 12490715 Fournier HN Dupe Manet S Bouvard D Lacombe ML Marie C Block MR Albiges Rizo C June 2002 Integrin cytoplasmic domain associated protein 1alpha ICAP 1alpha interacts directly with the metastasis suppressor nm23 H2 and both proteins are targeted to newly formed cell adhesion sites upon integrin engagement J Biol Chem 277 23 20895 902 doi 10 1074 jbc M200200200 PMID 11919189 Rual JF Venkatesan K Hao T Hirozane Kishikawa T Dricot A Li N Berriz GF Gibbons FD Dreze M Ayivi Guedehoussou N Klitgord N Simon C Boxem M Milstein S Rosenberg J Goldberg DS Zhang LV Wong SL Franklin G Li S Albala JS Lim J Fraughton C Llamosas E Cevik S Bex C Lamesch P Sikorski RS Vandenhaute J Zoghbi HY Smolyar A Bosak S Sequerra R Doucette Stamm L Cusick ME Hill DE Roth FP Vidal M October 2005 Towards a proteome scale map of the human protein protein interaction network Nature 437 7062 1173 8 Bibcode 2005Natur 437 1173R doi 10 1038 nature04209 PMID 16189514 S2CID 4427026 Negroni A Venturelli D Tanno B Amendola R Ransac S Cesi V Calabretta B Raschella G September 2000 Neuroblastoma specific effects of DR nm23 and its mutant forms on differentiation and apoptosis Cell Death Differ 7 9 843 50 doi 10 1038 sj cdd 4400720 PMID 11042679 Chakravarti D Hong R March 2003 SET ting the stage for life and death Cell 112 5 589 91 doi 10 1016 s0092 8674 03 00151 x PMID 12628178 S2CID 16423565 a b Paravicini G Steinmayr M Andre E Becker Andre M October 1996 The metastasis suppressor candidate nucleotide diphosphate kinase NM23 specifically interacts with members of the ROR RZR nuclear orphan receptor subfamily Biochem Biophys Res Commun 227 1 82 7 doi 10 1006 bbrc 1996 1471 PMID 8858107 Nosaka K Kawahara M Masuda M Satomi Y Nishino H February 1998 Association of nucleoside diphosphate kinase nm23 H2 with human telomeres Biochem Biophys Res Commun 243 2 342 8 doi 10 1006 bbrc 1997 8097 PMID 9480811 Further reading editFreije JM MacDonald NJ Steeg PS 1998 Nm23 and tumour metastasis basic and translational advances Biochem Soc Symp 63 261 71 PMID 9513729 Roymans D Willems R Van Blockstaele DR Slegers H 2002 Nucleoside diphosphate kinase NDPK NM23 and the waltz with multiple partners possible consequences in tumor metastasis Clin Exp Metastasis 19 6 465 76 doi 10 1023 A 1020396722860 PMID 12405283 S2CID 21876557 Tee YT Chen GD Lin LY Ko JL Wang PH 2006 Nm23 H1 a metastasis associated gene Taiwan J Obstet Gynecol 45 2 107 13 doi 10 1016 S1028 4559 09 60206 0 PMID 17197349 Gilles AM Presecan E Vonica A Lascu I 1991 Nucleoside diphosphate kinase from human erythrocytes Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme J Biol Chem 266 14 8784 9 doi 10 1016 S0021 9258 18 31515 1 PMID 1851158 Leone A McBride OW Weston A Wang MG Anglard P Cropp CS Goepel JR Lidereau R Callahan R Linehan WM 1991 Somatic allelic deletion of nm23 in human cancer Cancer Res 51 9 2490 3 PMID 2015608 Hailat N Keim DR Melhem RF Zhu XX Eckerskorn C Brodeur GM Reynolds CP Seeger RC Lottspeich F Strahler JR 1991 High levels of p19 nm23 protein in neuroblastoma are associated with advanced stage disease and with N myc gene amplification J Clin Invest 88 1 341 5 doi 10 1172 JCI115299 PMC 296039 PMID 2056128 Rosengard AM Krutzsch HC Shearn A Biggs JR Barker E Margulies IM King CR Liotta LA Steeg PS 1989 Reduced Nm23 Awd protein in tumour metastasis and aberrant Drosophila development Nature 342 6246 177 80 Bibcode 1989Natur 342 177R doi 10 1038 342177a0 PMID 2509941 S2CID 4340066 Wang L Patel U Ghosh L Chen HC Banerjee S 1993 Mutation in the nm23 gene is associated with metastasis in colorectal cancer Cancer Res 53 4 717 20 PMID 7916650 Chang CL Zhu XX Thoraval DH Ungar D Rawwas J Hora N Strahler JR Hanash SM Radany E 1994 Nm23 H1 mutation in neuroblastoma PDF Nature 370 6488 335 6 Bibcode 1994Natur 370 335C doi 10 1038 370335a0 hdl 2027 42 62612 PMID 8047138 S2CID 4356706 MacDonald NJ De la Rosa A Benedict MA Freije JM Krutsch H Steeg PS 1993 A serine phosphorylation of Nm23 and not its nucleoside diphosphate kinase activity correlates with suppression of tumor metastatic potential J Biol Chem 268 34 25780 9 doi 10 1016 S0021 9258 19 74458 5 PMID 8245015 Postel EH Berberich SJ Flint SJ Ferrone CA 1993 Human c myc transcription factor PuF identified as nm23 H2 nucleoside diphosphate kinase a candidate suppressor of tumor metastasis Science 261 5120 478 80 Bibcode 1993Sci 261 478P doi 10 1126 science 8392752 PMID 8392752 Sudbrak R Golla A Hogan K Powers P Gregg R Du Chesne I Lehmann Horn F Deufel T 1993 Exclusion of malignant hyperthermia susceptibility MHS from a putative MHS2 locus on chromosome 17q and of the alpha 1 beta 1 and gamma subunits of the dihydropyridine receptor calcium channel as candidates for the molecular defect PDF Hum Mol Genet 2 7 857 62 doi 10 1093 hmg 2 7 857 PMID 8395939 S2CID 86750140 Archived from the original PDF on 2020 02 07 MacDonald NJ Freije JM Stracke ML Manrow RE Steeg PS 1996 Site directed mutagenesis of nm23 H1 Mutation of proline 96 or serine 120 abrogates its motility inhibitory activity upon transfection into human breast carcinoma cells J Biol Chem 271 41 25107 16 doi 10 1074 jbc 271 41 25107 PMID 8810265 Paravicini G Steinmayr M Andre E Becker Andre M 1996 The metastasis suppressor candidate nucleotide diphosphate kinase NM23 specifically interacts with members of the ROR RZR nuclear orphan receptor subfamily Biochem Biophys Res Commun 227 1 82 7 doi 10 1006 bbrc 1996 1471 PMID 8858107 Nosaka K Kawahara M Masuda M Satomi Y Nishino H 1998 Association of nucleoside diphosphate kinase nm23 H2 with human telomeres Biochem Biophys Res Commun 243 2 342 8 doi 10 1006 bbrc 1997 8097 PMID 9480811 Schaertl S Konrad M Geeves MA 1998 Substrate specificity of human nucleoside diphosphate kinase revealed by transient kinetic analysis J Biol Chem 273 10 5662 9 doi 10 1074 jbc 273 10 5662 PMID 9488696 Willems R Van Bockstaele DR Lardon F Lenjou M Nijs G Snoeck HW Berneman ZN Slegers H 1998 Decrease in nucleoside diphosphate kinase NDPK nm23 expression during hematopoietic maturation J Biol Chem 273 22 13663 8 doi 10 1074 jbc 273 22 13663 PMID 9593706 Manda R Kohno T Matsuno Y Takenoshita S Kuwano H Yokota J 1999 Identification of genes SPON2 and C20orf2 differentially expressed between cancerous and noncancerous lung cells by mRNA differential display Genomics 61 1 5 14 doi 10 1006 geno 1999 5939 PMID 10512675 Chicco Davide Sanavia Tiziana Jurman Giuseppe 4 March 2023 Signature literature review reveals AHCY DPYSL3 and NME1 as the most recurrent prognostic genes for neuroblastoma BioData Mining 16 1 7 doi 10 1186 s13040 023 00325 1 eISSN 1756 0381 PMC 9985261 PMID 36870971 Retrieved from https en wikipedia org w index php title NME1 amp oldid 1179507582, wikipedia, wiki, book, books, library,

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