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Wikipedia

Metaphysis

The metaphysis is the neck portion of a long bone between the epiphysis and the diaphysis.[1] It contains the growth plate, the part of the bone that grows during childhood, and as it grows it ossifies near the diaphysis and the epiphyses. The metaphysis contains a diverse population of cells including mesenchymal stem cells, which give rise to bone and fat cells, as well as hematopoietic stem cells which give rise to a variety of blood cells as well as bone-destroying cells called osteoclasts. Thus the metaphysis contains a highly metabolic set of tissues including trabecular (spongy) bone, blood vessels , as well as Marrow Adipose Tissue (MAT).

Metaphysis
Structure of a long bone, showing the metaphysis
Details
Pronunciation/mətˈæfɪsɪs/
Part ofLong bones
Identifiers
Latinmetaphysis
TA98A02.0.00.022
TA2392
FMA24014
Anatomical terminology
[edit on Wikidata]

The metaphysis may be divided anatomically into three components based on tissue content: a cartilaginous component (epiphyseal plate), a bony component (metaphysis) and a fibrous component surrounding the periphery of the plate. The growth plate synchronizes chondrogenesis with osteogenesis or interstitial cartilage growth with both appositional bone elongation in conjunction with growth in width, so bearing load and responding to local and systemic forces and factors balance one another mechanically.

During childhood, the growth plate contains the connecting cartilage enabling the bone to grow; at adulthood (between the ages of 18 to 25 years), the components of the growth plate stop growing altogether and completely ossify into solid bone.[2] In an adult, the metaphysis functions to transfer loads from weight-bearing joint surfaces to the diaphysis.[3]

Clinical significance

 
An X ray demonstrating the characteristic finding of lead poisoning in humans—dense metaphyseal lines.

Because of their rich blood supply and vascular stasis, metaphyses of long bones are prone to hematogenous spread of osteomyelitis in children.[4]

Metaphyseal tumors or lesions include osteosarcoma, chondrosarcoma, fibrosarcoma, osteoblastoma, enchondroma, fibrous dysplasia, simple bone cyst, aneurysmal bone cyst, non-ossifying fibroma, and osteoid osteoma.[5]

One of the clinical signs of rickets that doctors look for is cupping and fraying at the metaphyses when seen on X-ray.

See also

References

  1. ^ Dorland's Pocket Medical Dictionary, 27th edition
  2. ^ Visual dictionary of Merriam-Webster http://visual.merriam-webster.com/human-being/anatomy/skeleton/parts-long-bone.php
  3. ^ Encyclopædia Britannica, http://www.britannica.com/EBchecked/topic/377978/metaphysis
  4. ^ Luqmani, Raashid; Robb, James; Daniel, Porter; Benjamin, Joseph (2013). Orthopaedics, Trauma and Rheumatology (second ed.). Mosby. p. 96. ISBN 9780723436805.
  5. ^ . Archived from the original on 2009-03-06. Retrieved 2009-03-12.

External links

  • - Comparative Organology at University of California, Davis - "Bone, structure (Gross, Low)"

metaphysis, confused, with, metaphysics, metaphysis, neck, portion, long, bone, between, epiphysis, diaphysis, contains, growth, plate, part, bone, that, grows, during, childhood, grows, ossifies, near, diaphysis, epiphyses, metaphysis, contains, diverse, popu. Not to be confused with Metaphysics The metaphysis is the neck portion of a long bone between the epiphysis and the diaphysis 1 It contains the growth plate the part of the bone that grows during childhood and as it grows it ossifies near the diaphysis and the epiphyses The metaphysis contains a diverse population of cells including mesenchymal stem cells which give rise to bone and fat cells as well as hematopoietic stem cells which give rise to a variety of blood cells as well as bone destroying cells called osteoclasts Thus the metaphysis contains a highly metabolic set of tissues including trabecular spongy bone blood vessels as well as Marrow Adipose Tissue MAT MetaphysisStructure of a long bone showing the metaphysisDetailsPronunciation m e t ˈ ae f ɪ s ɪ s Part ofLong bonesIdentifiersLatinmetaphysisTA98A02 0 00 022TA2392FMA24014Anatomical terminology edit on Wikidata The metaphysis may be divided anatomically into three components based on tissue content a cartilaginous component epiphyseal plate a bony component metaphysis and a fibrous component surrounding the periphery of the plate The growth plate synchronizes chondrogenesis with osteogenesis or interstitial cartilage growth with both appositional bone elongation in conjunction with growth in width so bearing load and responding to local and systemic forces and factors balance one another mechanically During childhood the growth plate contains the connecting cartilage enabling the bone to grow at adulthood between the ages of 18 to 25 years the components of the growth plate stop growing altogether and completely ossify into solid bone 2 In an adult the metaphysis functions to transfer loads from weight bearing joint surfaces to the diaphysis 3 Contents 1 Clinical significance 2 See also 3 References 4 External linksClinical significance Edit An X ray demonstrating the characteristic finding of lead poisoning in humans dense metaphyseal lines Because of their rich blood supply and vascular stasis metaphyses of long bones are prone to hematogenous spread of osteomyelitis in children 4 Metaphyseal tumors or lesions include osteosarcoma chondrosarcoma fibrosarcoma osteoblastoma enchondroma fibrous dysplasia simple bone cyst aneurysmal bone cyst non ossifying fibroma and osteoid osteoma 5 One of the clinical signs of rickets that doctors look for is cupping and fraying at the metaphyses when seen on X ray See also EditDiaphysis EpiphysisReferences Edit Dorland s Pocket Medical Dictionary 27th edition Visual dictionary of Merriam Webster http visual merriam webster com human being anatomy skeleton parts long bone php Encyclopaedia Britannica http www britannica com EBchecked topic 377978 metaphysis Luqmani Raashid Robb James Daniel Porter Benjamin Joseph 2013 Orthopaedics Trauma and Rheumatology second ed Mosby p 96 ISBN 9780723436805 New Jersey Medical School Pathology Department Introductory Course on Bone Tumours Archived from the original on 2009 03 06 Retrieved 2009 03 12 External links EditAnatomy photo Musculoskeletal bone structure0 structure2 Comparative Organology at University of California Davis Bone structure Gross Low Retrieved from https en wikipedia org w index php title Metaphysis amp oldid 1097209717, wikipedia, wiki, book, books, library,

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