Maxwell Myer Wintrobe (October 27, 1901 – December 9, 1986) was an Austrian-born American physician who was a 20th-century authority in the medical field of hematology. His 1942 textbook on hematology, Clinical Hematology, was the first dedicated work in the field and he contributed to the diagnostic approach of anemia and copper metabolism, amongst many other achievements.
Wintrobe was born in Austria (Fred 2007), contrary to previous historical records. His family name reflects the Jewish origin of his parents, Herman and Ethel, who emigrated from Austria with their son Max in 1906. Canadian census records show that the family arrived in Halifax, Nova Scotia in 1906, where Ethel's four brothers were living at the time. The family moved to Manitoba in 1912. Wintrobe attended the University of Manitoba from the early age of 15, where he graduated in 1921 and obtained his M.D. in 1926. He married Becky Zamphir, and moved to the United States, where he obtained a PhD at Tulane University in New Orleans, Louisiana in 1929; his thesis was titled "The Erythrocyte in Man".
Initially working in Johns Hopkins Hospital, where he served on the faculty, he was appointed as professor of internal medicine at the College of Medicine of the University of Utah in 1943; he also served as the first Chairman of the Department of Medicine and physician-in-chief for the Salt Lake County General Hospital.
In Salt Lake City he led research in hereditary and metabolic disorders (1945–1973) and cardiovascular research (1969–1973). He retired officially in 1965, but remained in function until 1973 (Valentine 1990). In that year he was elected to the National Academy of Sciences.
Wintrobe was the principal editor of Clinical Hematology, which first appeared in 1942 and is in its eleventh edition (Greer et al. as of 2003[update]), still bearing his name. He was part of the team that pioneered the use of chemotherapy in cancer (Goodman et al. 1946). He was one of the editors of the first edition (1950) of Harrison's Principles of Internal Medicine.
In 1980, he published Blood, pure and eloquent, and in 1985 he published Hematology, the Blossoming of a Science. Both works are historical overviews of his field.
Referencesedit
Fred, H. L. (2007). "Maxwell Myer Wintrobe: New history and a new appreciation". Texas Heart Institute Journal. 34 (3): 328–335. PMC1995040. PMID 17948084.
Goodman, L. S.; Wintrobe, M. M.; Dameshek, W.; Goodman, M. J.; Gilman, A.; McLennan, M. T. (1984). "Landmark article Sept. 21, 1946: Nitrogen mustard therapy. Use of methyl-bis(beta-chloroethyl)amine hydrochloride and tris(beta-chloroethyl)amine hydrochloride for Hodgkin's disease, lymphosarcoma, leukemia and certain allied and miscellaneous disorders. By Louis S. Goodman, Maxwell M. Wintrobe, William Dameshek, Morton J. Goodman, Alfred Gilman and Margaret T. McLennan". JAMA: The Journal of the American Medical Association. 251 (17): 2255–2261. doi:10.1001/jama.251.17.2255. PMID 6368885.
Valentine WN. Maxwell Myer Wintrobe. In "Biographical Memoirs". National Academy of Sciences 1990;59:446-472. ISBN0-309-04198-8. Fulltext.
Wintrobe, M. M. (1990). "The size and hemoglobin content of the erythrocyte. Methods of determination and clinical application. 1932". The Journal of Laboratory and Clinical Medicine. 115 (3): 374–387. PMID 2179436.
Wintrobe MM. Blood, pure and eloquent; a story of discovery, of people and ideas. New York: McGraw-Hill, 1980. ISBN0-07-071135-6.
Wintrobe MM. Hematology, the Blossoming of a Science: A Story of Inspiration and Effort. Lippincott Williams & Wilkins, 1985. ISBN0-8121-0961-9.
External linksedit
at the University of Utah
January 01, 1970
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This article includes a list of references related reading or external links but its sources remain unclear because it lacks inline citations Please help improve this article by introducing more precise citations January 2013 Learn how and when to remove this message Maxwell Myer Wintrobe October 27 1901 December 9 1986 was an Austrian born American physician who was a 20th century authority in the medical field of hematology His 1942 textbook on hematology Clinical Hematology was the first dedicated work in the field and he contributed to the diagnostic approach of anemia and copper metabolism amongst many other achievements Maxwell WintrobeBorn 1901 10 27 27 October 1901Austria Austria HungaryDied9 December 1986 1986 12 09 aged 85 OccupationPhysicianKnown forWintrobe hematocrit method introduced in 1929 Contents 1 Biography 2 Works 3 References 4 External linksBiography editWintrobe was born in Austria Fred 2007 contrary to previous historical records His family name reflects the Jewish origin of his parents Herman and Ethel who emigrated from Austria with their son Max in 1906 Canadian census records show that the family arrived in Halifax Nova Scotia in 1906 where Ethel s four brothers were living at the time The family moved to Manitoba in 1912 Wintrobe attended the University of Manitoba from the early age of 15 where he graduated in 1921 and obtained his M D in 1926 He married Becky Zamphir and moved to the United States where he obtained a PhD at Tulane University in New Orleans Louisiana in 1929 his thesis was titled The Erythrocyte in Man Initially working in Johns Hopkins Hospital where he served on the faculty he was appointed as professor of internal medicine at the College of Medicine of the University of Utah in 1943 he also served as the first Chairman of the Department of Medicine and physician in chief for the Salt Lake County General Hospital In Salt Lake City he led research in hereditary and metabolic disorders 1945 1973 and cardiovascular research 1969 1973 He retired officially in 1965 but remained in function until 1973 Valentine 1990 In that year he was elected to the National Academy of Sciences Works editIn New Orleans Wintrobe pioneered new ways of measuring the hematocrit including what are now known as Wintrobe indices mean cell volume mean cell hemoglobin and mean cell hemoglobin concentration all quantitative measures of the red blood cell population Wintrobe 1932 Much of this work continued in Hopkins and Utah where he also worked on pernicious anemia copper metabolism and Wilson s disease sickle cell disease and other anemias Wintrobe was the principal editor of Clinical Hematology which first appeared in 1942 and is in its eleventh edition Greer et al as of 2003 update still bearing his name He was part of the team that pioneered the use of chemotherapy in cancer Goodman et al 1946 He was one of the editors of the first edition 1950 of Harrison s Principles of Internal Medicine In 1980 he published Blood pure and eloquent and in 1985 he published Hematology the Blossoming of a Science Both works are historical overviews of his field References editFred H L 2007 Maxwell Myer Wintrobe New history and a new appreciation Texas Heart Institute Journal 34 3 328 335 PMC 1995040 PMID 17948084 Goodman L S Wintrobe M M Dameshek W Goodman M J Gilman A McLennan M T 1984 Landmark article Sept 21 1946 Nitrogen mustard therapy Use of methyl bis beta chloroethyl amine hydrochloride and tris beta chloroethyl amine hydrochloride for Hodgkin s disease lymphosarcoma leukemia and certain allied and miscellaneous disorders By Louis S Goodman Maxwell M Wintrobe William Dameshek Morton J Goodman Alfred Gilman and Margaret T McLennan JAMA The Journal of the American Medical Association 251 17 2255 2261 doi 10 1001 jama 251 17 2255 PMID 6368885 Greer JP Foerster J Lukens JN Wintrobe s Clinical Hematology 11th edition Lippincott Williams amp Wilkins 2003 ISBN 0 7817 3650 1 Valentine WN Maxwell Myer Wintrobe In Biographical Memoirs National Academy of Sciences 1990 59 446 472 ISBN 0 309 04198 8 Fulltext Wintrobe M M 1990 The size and hemoglobin content of the erythrocyte Methods of determination and clinical application 1932 The Journal of Laboratory and Clinical Medicine 115 3 374 387 PMID 2179436 Wintrobe MM Blood pure and eloquent a story of discovery of people and ideas New York McGraw Hill 1980 ISBN 0 07 071135 6 Wintrobe MM Hematology the Blossoming of a Science A Story of Inspiration and Effort Lippincott Williams amp Wilkins 1985 ISBN 0 8121 0961 9 External links editCollection of papers at the University of Utah Retrieved from https en wikipedia org w index php title Maxwell Wintrobe amp oldid 1095302764, wikipedia, wiki, book, books, library,
