In this Spanish name, the first or paternal surname is Patarroyo and the second or maternal family name is Murillo.
Manuel Elkin Patarroyo Murillo (born November 3, 1946)[1] is a Colombian Professor of Pathology and Immunology who made the world's first attempt to create a synthetic vaccine against the protozoal parasite Plasmodium falciparum, the cause of severe malaria,[2] and responsible for the death of ~1.5 million people per year in tropical and subtropical regions, including parts of the Americas, Asia, and Africa.
The vaccine candidate, first developed in 1987 in Colombia, was evaluated in clinical trials carried out by the WHO in Gambia, Tanzania and Thailand, and had mixed results.[3] In 2009, a comprehensive Cochrane review assessed the SPf66 as being not efficacious in Africa and Asia, and as having a low but statistically significant efficacy of 28% in South America.[4] Researchers and vaccine developers have been working on many approaches to bring forward the availability of a malaria vaccine."[5] More research and clinical trials are required for a universal vaccine to be implemented.
Patarroyo is a recipient of the TWAS Prize (1998).[6]
Scientific workedit
Patarroyo started experimenting with animals since the decade of the 1980s, paying for wild monkeys captured in the Amazonian rainforest generating illegal traffic carried on by indigenous people who hunt the elusive monkeys for sale.[7]
The Corporation for the Sustainable Development of the South of the Amazon (Corpoamazonía), has opened a file (number 000102) for complaints about irregularities committed by the FIDIC (Fundación Instituto de Inmunología de Colombia) research team led by Manuel Elkin Patarroyo. The Ministry of Environment, Housing and Territorial Development of Colombia carried out an investigation motivated by the Corpoamazonía denunciations, in which there were evidenced within the facilities of the FIDIC 627 monkeys of the species Aotus nancymaae [Night_monkey], which had only been registered in Brazil and Peru and not in Colombian territory.[8] The export of these animals was not registered in the permits of the administrative authorities. For 2008, the alleged illegal trade in this animal species is under investigation by the Colombian government against the FIDIC. On 2012 the Administrative Court of Cundinamarca in Colombia revoked the permits of experimenting with 4,000 night monkeys (Aotus trivirgatus) for Patarroyo's jungle laboratory[9] but in March 2015 the decision was reversed and the experiments with primates were allowed to continue.
In April 2016, Dr. Patarroyo was awarded the honorary doctorate from the Ricardo Palma University, in whose official ceremony there was a controversy against defenders of the biodiversity of Peruvian wildlife. Dr. Patarroyo, using in its clinical trials species of green-tailed monkeys Aotus nancymaae, using more than 4000 specimens, which returned to its wild state without spleen, deprived of immune system,[10] reason why it was recriminated in the mentioned act . The ecologists supported their accusations based on allegations in SERFOR of Peru, for which the investigator had no response.
In November 2016 a Colombian journalistic investigation reveals the traffic and the environmental impact of Patarroyo's investigation[11]
^Holloway, M. (1996) Profile: Manuel Elkin Patarroyo – The Man Who Would Conquer Malaria, Scientific American275(6), 52-56.
^- Susan Aldridge, Magic Molecules: How Drugs Work (Cambridge University Press, 1998), p. 89
^- Graves, P. M. and Gelband, H. (2009) Vaccines for preventing malaria (SPf66) (Review), The Cochrane Library 2009, (2), pp.1-38. 2011-07-20 at the Wayback Machine
^Hunting of the nocturnal monkey for scientific purposes threatens the species and devastates the environment(Spanish)
External linksedit
Structural and Immunological Principles Leading to Chemically Synthesized, Multiantigeni c, Multistage, Minimal Subunit-Based Vaccine Development, abstract of article in Chemical Reviews, from de American Chemical Society.
Emerging Rules for Subunit-Based, Multiantigenic, Multistage Chemically Synthesized Vaccines, abstract of article in Accounts of Chemical Research, from the American Chemical Society.
Toward A New Generation Of Vaccines For Malaria And Other Diseases in 'Science Daily'.
Race for Malaria Money
Guardian Unlimited: Scientist whose dream of beating disease came true
November 23, 2023
manuel, elkin, patarroyo, this, spanish, name, first, paternal, surname, patarroyo, second, maternal, family, name, murillo, murillo, born, november, 1946, colombian, professor, pathology, immunology, made, world, first, attempt, create, synthetic, vaccine, ag. In this Spanish name the first or paternal surname is Patarroyo and the second or maternal family name is Murillo Manuel Elkin Patarroyo Murillo born November 3 1946 1 is a Colombian Professor of Pathology and Immunology who made the world s first attempt to create a synthetic vaccine against the protozoal parasite Plasmodium falciparum the cause of severe malaria 2 and responsible for the death of 1 5 million people per year in tropical and subtropical regions including parts of the Americas Asia and Africa Manuel Elkin PatarroyoBornManuel Elkin Patarroyo Murillo 1946 11 03 November 3 1946 age 77 Ataco Tolima ColombiaEducationNational University of Colombia MD Known forSPf66 Malaria vaccineMedical careerProfessionPhysician scientistInstitutionsHospital San Juan de Dios National University of ColombiaSub specialtiesPathologistResearchImmunologyAwardsPrince of Asturias Awards 1994 Robert Koch Prize 1994 The vaccine candidate first developed in 1987 in Colombia was evaluated in clinical trials carried out by the WHO in Gambia Tanzania and Thailand and had mixed results 3 In 2009 a comprehensive Cochrane review assessed the SPf66 as being not efficacious in Africa and Asia and as having a low but statistically significant efficacy of 28 in South America 4 Researchers and vaccine developers have been working on many approaches to bring forward the availability of a malaria vaccine 5 More research and clinical trials are required for a universal vaccine to be implemented Patarroyo is a recipient of the TWAS Prize 1998 6 Scientific work editPatarroyo started experimenting with animals since the decade of the 1980s paying for wild monkeys captured in the Amazonian rainforest generating illegal traffic carried on by indigenous people who hunt the elusive monkeys for sale 7 The Corporation for the Sustainable Development of the South of the Amazon Corpoamazonia has opened a file number 000102 for complaints about irregularities committed by the FIDIC Fundacion Instituto de Inmunologia de Colombia research team led by Manuel Elkin Patarroyo The Ministry of Environment Housing and Territorial Development of Colombia carried out an investigation motivated by the Corpoamazonia denunciations in which there were evidenced within the facilities of the FIDIC 627 monkeys of the species Aotus nancymaae Night monkey which had only been registered in Brazil and Peru and not in Colombian territory 8 The export of these animals was not registered in the permits of the administrative authorities For 2008 the alleged illegal trade in this animal species is under investigation by the Colombian government against the FIDIC On 2012 the Administrative Court of Cundinamarca in Colombia revoked the permits of experimenting with 4 000 night monkeys Aotus trivirgatus for Patarroyo s jungle laboratory 9 but in March 2015 the decision was reversed and the experiments with primates were allowed to continue In April 2016 Dr Patarroyo was awarded the honorary doctorate from the Ricardo Palma University in whose official ceremony there was a controversy against defenders of the biodiversity of Peruvian wildlife Dr Patarroyo using in its clinical trials species of green tailed monkeys Aotus nancymaae using more than 4000 specimens which returned to its wild state without spleen deprived of immune system 10 reason why it was recriminated in the mentioned act The ecologists supported their accusations based on allegations in SERFOR of Peru for which the investigator had no response In November 2016 a Colombian journalistic investigation reveals the traffic and the environmental impact of Patarroyo s investigation 11 References edit Fundacion Principe de Asturias Manuel Elkin Patarroyo Archived 2008 05 13 at the Wayback Machine Spanish Premiados Investigacion Cientifica y Tecnica 1994 Holloway M 1996 Profile Manuel Elkin Patarroyo The Man Who Would Conquer Malaria Scientific American 275 6 52 56 Susan Aldridge Magic Molecules How Drugs Work Cambridge University Press 1998 p 89 Graves P M and Gelband H 2009 Vaccines for preventing malaria SPf66 Review The Cochrane Library 2009 2 pp 1 38 Archived 2011 07 20 at the Wayback Machine WHO 2010 Tables of Malaria Vaccine Projects Globally Updated December 2010 Initiative for Vaccine Research Prizes and Awards The World Academy of Sciences 2016 Environmental Crime in Latin America The Theft of Nature and the Poisoning on the land Primate Rights vs Research Battle in Colombian Rainforest A legal victory for night monkeys International Primate Protection League Controversy Still Surrounds Malaria Vaccine Hunting of the nocturnal monkey for scientific purposes threatens the species and devastates the environment Spanish External links editStructural and Immunological Principles Leading to Chemically Synthesized Multiantigeni c Multistage Minimal Subunit Based Vaccine Development abstract of article in Chemical Reviews from de American Chemical Society Emerging Rules for Subunit Based Multiantigenic Multistage Chemically Synthesized Vaccines abstract of article in Accounts of Chemical Research from the American Chemical Society Toward A New Generation Of Vaccines For Malaria And Other Diseases in Science Daily Race for Malaria Money Scientists Herald Malaria Breakthrough Guardian Unlimited Scientist whose dream of beating disease came true Tables of Malaria Vaccine Projects Retrieved from https en wikipedia org w index php title Manuel Elkin Patarroyo amp oldid 1180902606, wikipedia, wiki, book, books, library,
