This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is GTP:alpha-D-mannose-1-phosphate guanylyltransferase. Other names in common use include GTP-mannose-1-phosphate guanylyltransferase, PIM-GMP (phosphomannose isomerase-guanosine 5'-diphospho-D-mannose, pyrophosphorylase), GDP-mannose pyrophosphorylase, guanosine 5'-diphospho-D-mannose pyrophosphorylase, guanosine diphosphomannose pyrophosphorylase, guanosine triphosphate-mannose 1-phosphate guanylyltransferase, and mannose 1-phosphate guanylyltransferase (guanosine triphosphate). This enzyme participates in fructose and mannose metabolism.
Structural studiesedit
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2CU2.
Referencesedit
Munch-Peterson A (1955). "Enzymatic synthesis and phosphorolysis of guanosine diphosphate mannose". Arch. Biochem. Biophys. 55 (2): 592–593. doi:10.1016/0003-9861(55)90441-0.
PREISS J, WOOD E (1964). "Sugar Nucleotide Reactions in Arthrobacter. I. Guanosine Diphosphate Mannose Pyrophosphorylase: Purification and Properties". J. Biol. Chem. 239: 3119–26. PMID 14245350.
mannose, phosphate, guanylyltransferase, enzymology, mannose, phosphate, guanylyltransferase, enzyme, that, catalyzes, chemical, reactionmannose, phosphate, guanylyltransferaseidentifiersec, 13cas, 37278, 3databasesintenzintenz, viewbrendabrenda, entryexpasyni. In enzymology a mannose 1 phosphate guanylyltransferase EC 2 7 7 13 is an enzyme that catalyzes the chemical reactionmannose 1 phosphate guanylyltransferaseIdentifiersEC no 2 7 7 13CAS no 37278 24 3DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumGene OntologyAmiGO QuickGOSearchPMCarticlesPubMedarticlesNCBIproteins GTP alpha D mannose 1 phosphate displaystyle rightleftharpoons diphosphate GDP mannoseThus the two substrates of this enzyme are GTP and alpha D mannose 1 phosphate whereas its two products are diphosphate and GDP mannose This enzyme belongs to the family of transferases specifically those transferring phosphorus containing nucleotide groups nucleotidyltransferases The systematic name of this enzyme class is GTP alpha D mannose 1 phosphate guanylyltransferase Other names in common use include GTP mannose 1 phosphate guanylyltransferase PIM GMP phosphomannose isomerase guanosine 5 diphospho D mannose pyrophosphorylase GDP mannose pyrophosphorylase guanosine 5 diphospho D mannose pyrophosphorylase guanosine diphosphomannose pyrophosphorylase guanosine triphosphate mannose 1 phosphate guanylyltransferase and mannose 1 phosphate guanylyltransferase guanosine triphosphate This enzyme participates in fructose and mannose metabolism Structural studies editAs of late 2007 only one structure has been solved for this class of enzymes with the PDB accession code 2CU2 References editMunch Peterson A 1955 Enzymatic synthesis and phosphorolysis of guanosine diphosphate mannose Arch Biochem Biophys 55 2 592 593 doi 10 1016 0003 9861 55 90441 0 PREISS J WOOD E 1964 Sugar Nucleotide Reactions in Arthrobacter I Guanosine Diphosphate Mannose Pyrophosphorylase Purification and Properties J Biol Chem 239 3119 26 PMID 14245350 Portal nbsp Biology This EC 2 7 enzyme related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Mannose 1 phosphate guanylyltransferase amp oldid 1172352958, wikipedia, wiki, book, books, library,
