microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding.
The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products.
The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.
mir6087, microrna, 6087, mirna, that, humans, encoded, gene, identifiersaliaseshsa, 6087microrna, 6087external, idsgenecards, orthologsspecieshumanmouseentrezn, aensembln, auniprotnan, arefseq, mrna, arefseq, protein, alocation, ucsc, apubmed, searchn, awikida. MicroRNA 6087 is a miRNA that in humans is encoded by the MIR6087 gene 1 MIR6087IdentifiersAliaseshsa mir 6087microRNA 6087External IDsGeneCards 1 OrthologsSpeciesHumanMouseEntrezn an aEnsembln an aUniProtnan aRefSeq mRNA n an aRefSeq protein n an aLocation UCSC n an aPubMed searchn an aWikidataView Edit HumanFunction editmicroRNAs miRNAs are short 20 24 nt non coding RNAs that are involved in post transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts pri miRNAs that can be either protein coding or non coding The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70 nt stem loop precursor miRNA pre miRNA which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star miRNA products The mature miRNA is incorporated into a RNA induced silencing complex RISC which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA The RefSeq represents the predicted microRNA stem loop References edit Entrez Gene MicroRNA 6087 Retrieved 2016 11 16 Further reading editThis article incorporates text from the United States National Library of Medicine which is in the public domain nbsp This article on a gene on the human X chromosome and or its associated protein is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title MIR6087 amp oldid 1079123235, wikipedia, wiki, book, books, library,
