^ abcGRCm38: Ensembl release 89: ENSMUSG00000031576 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Schreiber M, Wei A, Yuan A, Gaut J, Saito M, Salkoff L (February 1998). "Slo3, a novel pH-sensitive K+ channel from mammalian spermatocytes". J. Biol. Chem. 273 (6): 3509–16. doi:10.1074/jbc.273.6.3509. PMID 9452476.
^Wei AD, Gutman GA, Aldrich R, Chandy KG, Grissmer S, Wulff H (2005). "International Union of Pharmacology. LII. Nomenclature and molecular relationships of calcium-activated potassium channels". Pharmacol Rev. 57 (4): 463–72. doi:10.1124/pr.57.4.9. PMID 16382103. S2CID 8290401.
^Zhang X, Zeng X, Xia XM, Lingle CJ (September 2006). "pH-regulated Slo3 K+ channels: properties of unitary currents". J. Gen. Physiol. 128 (3): 301–15. doi:10.1085/jgp.200609551. PMC2151565. PMID 16940554.
^Zhang X, Zeng X, Lingle CJ (September 2006). "Slo3 K+ channels: voltage and pH dependence of macroscopic currents". J. Gen. Physiol. 128 (3): 317–36. doi:10.1085/jgp.200609552. PMC2151566. PMID 16940555.
Celia M. Santi, Alice Butler, Julia Kuhn, Aguan Wei, Lawrence Salkoff. Bovine and mouse SLO3 K+ channels: Evolutionary divergence points to a RCK1 region of critical function. J Biol Chem.284: 21589-98 (2009).
External linksedit
Overview of all the structural information available in the PDB for UniProt: A8MYU2 (Potassium channel subfamily U member 1) at the PDBe-KB.
Further readingedit
Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC139241. PMID 12477932.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC1356129. PMID 16344560.
Schreiber M, Wei A, Yuan A, et al. (1998). "Slo3, a novel pH-sensitive K+ channel from mammalian spermatocytes". J. Biol. Chem. 273 (6): 3509–16. doi:10.1074/jbc.273.6.3509. PMID 9452476.
Nusbaum C, Mikkelsen TS, Zody MC, et al. (2006). "DNA sequence and analysis of human chromosome 8". Nature. 439 (7074): 331–5. Bibcode:2006Natur.439..331N. doi:10.1038/nature04406. PMID 16421571.
Wei AD, Gutman GA, Aldrich R, et al. (2005). "International Union of Pharmacology. LII. Nomenclature and molecular relationships of calcium-activated potassium channels". Pharmacol. Rev. 57 (4): 463–72. doi:10.1124/pr.57.4.9. PMID 16382103. S2CID 8290401.
Celia M. Santi, Alice Butler, Julia Kuhn, Aguan Wei, Lawrence Salkoff. Bovine and mouse SLO3 K+ channels: Evolutionary divergence points to a RCK1 region of critical function. J Biol Chem.284: 21589-98 (2009).
This article on a gene on human chromosome 8 is a stub. You can help Wikipedia by expanding it.
kcnu1, potassium, channel, subfamily, member, also, known, gene, encoding, kca5, protein, available, structurespdbortholog, search, pdbe, rcsblist, codes4hpfidentifiersaliases, kcnmc1, kca5, kca5, kcnma3, slo3, potassium, calcium, activated, channel, subfamily. Potassium channel subfamily U member 1 also known as KCNU1 is a gene encoding the KCa5 1 protein 4 KCNU1Available structuresPDBOrtholog search PDBe RCSBList of PDB id codes4HPFIdentifiersAliasesKCNU1 KCNMC1 KCa5 KCa5 1 Kcnma3 Slo3 potassium calcium activated channel subfamily U member 1External IDsOMIM 615215 MGI 1202300 HomoloGene 7392 GeneCards KCNU1Gene location Mouse Chr Chromosome 8 mouse 1 Band8 8 A2Start26 339 651 bp 1 End26 427 967 bp 1 RNA expression patternBgeeHumanMouse ortholog Top expressed inspermbone marrow cellscaput epididymissubstantia nigramonocytemammary glandbreastsubcutaneous adipose tissuemale reproductive glandprostateTop expressed inspermatidseminiferous tubulespermatocytefacial motor nucleusislet of Langerhansmorulaanterior horn of spinal cordsuperior frontal gyrusblastocystneural tubeMore reference expression dataBioGPSn aGene ontologyMolecular functionvoltage gated potassium channel activity large conductance calcium activated potassium channel activity ion channel activity potassium channel activity voltage gated ion channel activity calcium activated potassium channel activity outward rectifier potassium channel activityCellular componentintegral component of membrane voltage gated potassium channel complex plasma membrane membraneBiological processpotassium ion transport regulation of ion transmembrane transport ion transport transmembrane transport potassium ion transmembrane transport sperm egg recognition reproductive process regulation of membrane potentialSources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez15785516532Ensembln aENSMUSG00000031576UniProtA8MYU2O54982RefSeq mRNA NM 001031836NM 008432RefSeq protein NP 001027006NP 032458Location UCSC n aChr 8 26 34 26 43 MbPubMed search 2 3 WikidataView Edit HumanView Edit Mouse Although this channel is structurally related to the calcium activated potassium channels it cannot be classified as such since it is activated by high intracellular pH and relatively insensitive to changes in calcium concentrations 5 6 7 References edit a b c GRCm38 Ensembl release 89 ENSMUSG00000031576 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Schreiber M Wei A Yuan A Gaut J Saito M Salkoff L February 1998 Slo3 a novel pH sensitive K channel from mammalian spermatocytes J Biol Chem 273 6 3509 16 doi 10 1074 jbc 273 6 3509 PMID 9452476 Wei AD Gutman GA Aldrich R Chandy KG Grissmer S Wulff H 2005 International Union of Pharmacology LII Nomenclature and molecular relationships of calcium activated potassium channels Pharmacol Rev 57 4 463 72 doi 10 1124 pr 57 4 9 PMID 16382103 S2CID 8290401 Zhang X Zeng X Xia XM Lingle CJ September 2006 pH regulated Slo3 K channels properties of unitary currents J Gen Physiol 128 3 301 15 doi 10 1085 jgp 200609551 PMC 2151565 PMID 16940554 Zhang X Zeng X Lingle CJ September 2006 Slo3 K channels voltage and pH dependence of macroscopic currents J Gen Physiol 128 3 317 36 doi 10 1085 jgp 200609552 PMC 2151566 PMID 16940555 Celia M Santi Alice Butler Julia Kuhn Aguan Wei Lawrence Salkoff Bovine and mouse SLO3 K channels Evolutionary divergence points to a RCK1 region of critical function J Biol Chem 284 21589 98 2009 External links editOverview of all the structural information available in the PDB for UniProt A8MYU2 Potassium channel subfamily U member 1 at the PDBe KB Further reading editStrausberg RL Feingold EA Grouse LH et al 2002 Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 99 26 16899 903 Bibcode 2002PNAS 9916899M doi 10 1073 pnas 242603899 PMC 139241 PMID 12477932 Kimura K Wakamatsu A Suzuki Y et al 2006 Diversification of transcriptional modulation large scale identification and characterization of putative alternative promoters of human genes Genome Res 16 1 55 65 doi 10 1101 gr 4039406 PMC 1356129 PMID 16344560 Schreiber M Wei A Yuan A et al 1998 Slo3 a novel pH sensitive K channel from mammalian spermatocytes J Biol Chem 273 6 3509 16 doi 10 1074 jbc 273 6 3509 PMID 9452476 Nusbaum C Mikkelsen TS Zody MC et al 2006 DNA sequence and analysis of human chromosome 8 Nature 439 7074 331 5 Bibcode 2006Natur 439 331N doi 10 1038 nature04406 PMID 16421571 Wei AD Gutman GA Aldrich R et al 2005 International Union of Pharmacology LII Nomenclature and molecular relationships of calcium activated potassium channels Pharmacol Rev 57 4 463 72 doi 10 1124 pr 57 4 9 PMID 16382103 S2CID 8290401 Celia M Santi Alice Butler Julia Kuhn Aguan Wei Lawrence Salkoff Bovine and mouse SLO3 K channels Evolutionary divergence points to a RCK1 region of critical function J Biol Chem 284 21589 98 2009 nbsp This article on a gene on human chromosome 8 is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title KCNU1 amp oldid 1081689568, 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