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Wikipedia

KCNH6

Potassium voltage-gated channel subfamily H member 6 is a protein that in humans is encoded by the KCNH6 gene.[5] The protein encoded by this gene is a voltage-gated potassium channel subunit.[5]

KCNH6
Identifiers
AliasesKCNH6, ERG-2, ERG2, HERG2, Kv11.2, hERG-2, potassium voltage-gated channel subfamily H member 6
External IDsOMIM: 608168 MGI: 2684139 HomoloGene: 32740 GeneCards: KCNH6
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001278919
NM_001278920
NM_030779
NM_173092

NM_001037712

RefSeq (protein)

NP_001265848
NP_001265849
NP_110406
NP_775115

n/a

Location (UCSC)Chr 17: 63.52 – 63.55 MbChr 11: 106.01 – 106.03 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References edit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000173826 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000001901 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

Further reading edit

  • Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ganetzky B, Robertson GA, Wilson GF, et al. (1999). "The eag family of K+ channels in Drosophila and mammals". Ann. N. Y. Acad. Sci. 868 (1): 356–69. Bibcode:1999NYASA.868..356G. doi:10.1111/j.1749-6632.1999.tb11297.x. PMID 10414305. S2CID 33512855.
  • Bauer CK, Wulfsen I, Schäfer R, et al. (2003). "HERG K(+) currents in human prolactin-secreting adenoma cells". Pflügers Arch. 445 (5): 589–600. doi:10.1007/s00424-002-0980-0. PMID 12634931. S2CID 20178757.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.

External links edit


kcnh6, potassium, voltage, gated, channel, subfamily, member, protein, that, humans, encoded, gene, protein, encoded, this, gene, voltage, gated, potassium, channel, subunit, identifiersaliases, erg2, herg2, kv11, herg, potassium, voltage, gated, channel, subf. Potassium voltage gated channel subfamily H member 6 is a protein that in humans is encoded by the KCNH6 gene 5 The protein encoded by this gene is a voltage gated potassium channel subunit 5 KCNH6IdentifiersAliasesKCNH6 ERG 2 ERG2 HERG2 Kv11 2 hERG 2 potassium voltage gated channel subfamily H member 6External IDsOMIM 608168 MGI 2684139 HomoloGene 32740 GeneCards KCNH6Gene location Human Chr Chromosome 17 human 1 Band17q23 3Start63 523 334 bp 1 End63 548 977 bp 1 Gene location Mouse Chr Chromosome 11 mouse 2 Band11 11 E1Start106 008 124 bp 2 End106 034 549 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed inkidneyanterior pituitaryislet of Langerhansjejunal mucosaprostateduodenumrenal medullarenal cortexkidney tubulehypothalamusTop expressed inislet of Langerhansoptic nervegranular layerPurkinje cellinferior colliculushypothalamuspontine nucleiatriuminternal granular layerneural tubeMore reference expression dataBioGPSn aGene ontologyMolecular functionvoltage gated potassium channel activity ion channel activity potassium channel activity voltage gated ion channel activityCellular componentintegral component of membrane plasma membrane membrane integral component of plasma membraneBiological processregulation of membrane potential potassium ion transport regulation of ion transmembrane transport ion transport transmembrane transport potassium ion transmembrane transport regulation of heart rate by cardiac conductionSources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez81033192775EnsemblENSG00000173826ENSMUSG00000001901UniProtQ9H252n aRefSeq mRNA NM 001278919NM 001278920NM 030779NM 173092NM 001037712RefSeq protein NP 001265848NP 001265849NP 110406NP 775115n aLocation UCSC Chr 17 63 52 63 55 MbChr 11 106 01 106 03 MbPubMed search 3 4 WikidataView Edit HumanView Edit MouseReferences edit a b c GRCh38 Ensembl release 89 ENSG00000173826 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000001901 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine a b Gutman GA Chandy KG Grissmer S Lazdunski M McKinnon D Pardo LA Robertson GA Rudy B Sanguinetti MC Stuhmer W Wang X Dec 2005 International Union of Pharmacology LIII Nomenclature and molecular relationships of voltage gated potassium channels Pharmacol Rev 57 4 473 508 doi 10 1124 pr 57 4 10 PMID 16382104 S2CID 219195192 Further reading editStrausberg RL Feingold EA Grouse LH et al 2002 Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 99 26 16899 903 Bibcode 2002PNAS 9916899M doi 10 1073 pnas 242603899 PMC 139241 PMID 12477932 Ganetzky B Robertson GA Wilson GF et al 1999 The eag family of K channels in Drosophila and mammals Ann N Y Acad Sci 868 1 356 69 Bibcode 1999NYASA 868 356G doi 10 1111 j 1749 6632 1999 tb11297 x PMID 10414305 S2CID 33512855 Bauer CK Wulfsen I Schafer R et al 2003 HERG K currents in human prolactin secreting adenoma cells Pflugers Arch 445 5 589 600 doi 10 1007 s00424 002 0980 0 PMID 12634931 S2CID 20178757 Gerhard DS Wagner L Feingold EA et al 2004 The Status Quality and Expansion of the NIH Full Length cDNA Project The Mammalian Gene Collection MGC Genome Res 14 10B 2121 7 doi 10 1101 gr 2596504 PMC 528928 PMID 15489334 Ota T Suzuki Y Nishikawa T et al 2004 Complete sequencing and characterization of 21 243 full length human cDNAs Nat Genet 36 1 40 5 doi 10 1038 ng1285 PMID 14702039 External links editKv11 2 Potassium Channel at the U S National Library of Medicine Medical Subject Headings MeSH KCNH6 protein human at the U S National Library of Medicine Medical Subject Headings MeSH nbsp This membrane protein related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title KCNH6 amp oldid 1115907055, wikipedia, wiki, book, books, library,

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