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Rifampicin/isoniazid/pyrazinamide

Rifampicin/isoniazid/pyrazinamide, also known as rifampin/isoniazid/pyrazinamide, and sold under the trade name Rifater, is a medication used to treat tuberculosis.[1] It is a fixed dose combination of rifampicin, isoniazid, and pyrazinamide.[1] It is used either by itself or along with other antituberculosis medication.[1] It is taken by mouth.[1]

Rifampicin/isoniazid/pyrazinamide
Combination of
RifampicinRifamycin antibiotic
IsoniazidAnti-tuberculosis medication
PyrazinamideAnti-tuberculosis medication
Clinical data
Trade namesRifater, Trifazid, others
AHFS/Drugs.comFDA Professional Drug Information
License data
  • US DailyMedRifampin_isoniazid_and_pyrazinamide
Routes of
administration
By mouth
ATC code
Legal status
Legal status
  • US: ℞-only
  • In general: ℞ (Prescription only)
Identifiers
CAS Number
  • 161935-14-4
PubChem CID
  • 6474062
ChemSpider
  • none
KEGG
  • D10210
  (verify)
3D structure Rifampicin/isoniazid/pyrazinamide

Side effects are those of the underlying medications.[1] These may include poor coordination, loss of appetite, nausea, joint pain, feeling tired, and numbness.[2] Severe side effects include liver problems.[3] Use in those under the age of 15 may not be appropriate.[3] It is unclear if use in pregnancy is safe for the baby.[3]

Rifampicin/isoniazid/pyrazinamide was approved for medical use in the United States in 1994.[3] It is on the World Health Organization's List of Essential Medicines.[4]

Medical uses edit

The hope of a fixed-dose combination pill is to increase the likelihood that people will take all of three medications.[5] Also, if people forget to take one or two of their drugs, they might not then develop resistance to the remaining drugs.[citation needed]

Society and culture edit

It is manufactured by Aventis.[citation needed]

See also edit

References edit

  1. ^ a b c d e World Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. p. 143. hdl:10665/44053. ISBN 9789241547659.
  2. ^ "Rifater Side Effects in Detail - Drugs.com". www.drugs.com. from the original on 21 December 2016. Retrieved 18 December 2016.
  3. ^ a b c d "Rifater - FDA prescribing information, side effects and uses". www.drugs.com. October 2016. from the original on 21 December 2016. Retrieved 18 December 2016.
  4. ^ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
  5. ^ Brown MJ, Sharma P, Bennett PN (30 July 2012). Clinical Pharmacology. Elsevier Health Sciences. p. 204. ISBN 978-0-7020-5113-5.

rifampicin, isoniazid, pyrazinamide, also, known, rifampin, isoniazid, pyrazinamide, sold, under, trade, name, rifater, medication, used, treat, tuberculosis, fixed, dose, combination, rifampicin, isoniazid, pyrazinamide, used, either, itself, along, with, oth. Rifampicin isoniazid pyrazinamide also known as rifampin isoniazid pyrazinamide and sold under the trade name Rifater is a medication used to treat tuberculosis 1 It is a fixed dose combination of rifampicin isoniazid and pyrazinamide 1 It is used either by itself or along with other antituberculosis medication 1 It is taken by mouth 1 Rifampicin isoniazid pyrazinamideCombination ofRifampicinRifamycin antibioticIsoniazidAnti tuberculosis medicationPyrazinamideAnti tuberculosis medicationClinical dataTrade namesRifater Trifazid othersAHFS Drugs comFDA Professional Drug InformationLicense dataUS DailyMed Rifampin isoniazid and pyrazinamideRoutes ofadministrationBy mouthATC codeJ04AM05 WHO Legal statusLegal statusUS only In general Prescription only IdentifiersCAS Number161935 14 4PubChem CID6474062ChemSpidernoneKEGGD10210 verify 3D structure Rifampicin isoniazid pyrazinamideSide effects are those of the underlying medications 1 These may include poor coordination loss of appetite nausea joint pain feeling tired and numbness 2 Severe side effects include liver problems 3 Use in those under the age of 15 may not be appropriate 3 It is unclear if use in pregnancy is safe for the baby 3 Rifampicin isoniazid pyrazinamide was approved for medical use in the United States in 1994 3 It is on the World Health Organization s List of Essential Medicines 4 Contents 1 Medical uses 2 Society and culture 3 See also 4 ReferencesMedical uses editThe hope of a fixed dose combination pill is to increase the likelihood that people will take all of three medications 5 Also if people forget to take one or two of their drugs they might not then develop resistance to the remaining drugs citation needed Society and culture editIt is manufactured by Aventis citation needed See also editTuberculosis treatment Rifampicin isoniazid ethambutolReferences edit a b c d e World Health Organization 2009 Stuart MC Kouimtzi M Hill SR eds WHO Model Formulary 2008 World Health Organization p 143 hdl 10665 44053 ISBN 9789241547659 Rifater Side Effects in Detail Drugs com www drugs com Archived from the original on 21 December 2016 Retrieved 18 December 2016 a b c d Rifater FDA prescribing information side effects and uses www drugs com October 2016 Archived from the original on 21 December 2016 Retrieved 18 December 2016 World Health Organization 2019 World Health Organization model list of essential medicines 21st list 2019 Geneva World Health Organization hdl 10665 325771 WHO MVP EMP IAU 2019 06 License CC BY NC SA 3 0 IGO Brown MJ Sharma P Bennett PN 30 July 2012 Clinical Pharmacology Elsevier Health Sciences p 204 ISBN 978 0 7020 5113 5 Portal nbsp Medicine nbsp This antiinfective drug article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Rifampicin isoniazid pyrazinamide amp oldid 1190628276, wikipedia, wiki, book, books, library,

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