Iroquois homeobox factors are a family of homeodomaintranscription factors that play a role in many developmental processes.[1][2] The loci were named for the flies carrying mutations in one of these genes, which are devoid of all bristles in the lateral part of the notum, leaving only a median stripe of bristles, similar to the Iroquois tribes which shaved all but a medial stripe of hairs on the head.[3]
Human genes that encode Iroquois homeobox factors include:[2]
^Gómez-Skarmeta JL, Modolell J (August 2002). "Iroquois genes: genomic organization and function in vertebrate neural development". Curr. Opin. Genet. Dev. 12 (4): 403–8. doi:10.1016/S0959-437X(02)00317-9. PMID 12100884.
^ abKerner P, Ikmi A, Coen D, Vervoort M (2009). "Evolutionary history of the iroquois/Irx genes in metazoans". BMC Evol. Biol. 9 (1): 74. Bibcode:2009BMCEE...9...74K. doi:10.1186/1471-2148-9-74. PMC2674049. PMID 19368711.
^Leyns L, Gómez-Skarmeta JL, Dambly-Chaudière C (September 1996). "iroquois: a prepattern gene that controls the formation of bristles on the thorax ofDrosophila". Mech. Dev. 59 (1): 63–72. doi:10.1016/0925-4773(96)00577-1. PMID 8892233. S2CID 8144286.
January 01, 1970
iroquois, homeobox, factor, family, homeodomain, transcription, factors, that, play, role, many, developmental, processes, loci, were, named, flies, carrying, mutations, these, genes, which, devoid, bristles, lateral, part, notum, leaving, only, median, stripe. Iroquois homeobox factors are a family of homeodomain transcription factors that play a role in many developmental processes 1 2 The loci were named for the flies carrying mutations in one of these genes which are devoid of all bristles in the lateral part of the notum leaving only a median stripe of bristles similar to the Iroquois tribes which shaved all but a medial stripe of hairs on the head 3 Human genes that encode Iroquois homeobox factors include 2 IrxA sub group IRX1 IRX2 IRX4 IrxB sub group IRX3 IRX5 IRX6 Iroquois like gene MKXReferences edit Gomez Skarmeta JL Modolell J August 2002 Iroquois genes genomic organization and function in vertebrate neural development Curr Opin Genet Dev 12 4 403 8 doi 10 1016 S0959 437X 02 00317 9 PMID 12100884 a b Kerner P Ikmi A Coen D Vervoort M 2009 Evolutionary history of the iroquois Irx genes in metazoans BMC Evol Biol 9 1 74 Bibcode 2009BMCEE 9 74K doi 10 1186 1471 2148 9 74 PMC 2674049 PMID 19368711 Leyns L Gomez Skarmeta JL Dambly Chaudiere C September 1996 iroquois a prepattern gene that controls the formation of bristles on the thorax ofDrosophila Mech Dev 59 1 63 72 doi 10 1016 0925 4773 96 00577 1 PMID 8892233 S2CID 8144286 Retrieved from https en wikipedia org w index php title Iroquois homeobox factor amp oldid 1217003551, wikipedia, wiki, book, books, library,
