Hyperuricosuria is a medical term referring to the presence of excessive amounts of uric acid in the urine. For men this is at a rate greater than 800 mg/day, and for women, 750 mg/day.[1] Notable direct causes of hyperuricosuria are dissolution of uric acid crystals in the kidneys or urinary bladder, and hyperuricemia. Notable indirect causes include uricosuric drugs, rapid breakdown of bodily tissues containing large quantities of DNA and RNA, and a diet high in purine.
Medications that may contribute to the cure or amelioration of hyperuricosuria include allopurinol which acts by inhibiting xanthine oxidase and reducing uric acid production.[2] Hyperuricosuria may be a medical sign of:
Acute hyperuricosuria is a common complication of tumor lysis syndrome. This syndrome appears not to contribute to gout and to uric acid nephrolithiasis, which is evidence that these two conditions have chronic, not acute, causes.
Chronic hyperuricosuria is associated with gout and uric acid nephrolithiasis.[3] However, both conditions can occur in the absence of hyperuricosuria. Treatment of gout with uricosuric drugs can lead to uric acid nephrolithiasis.
Treatment
If neither hyperuricemia nor gout is present, then the risk of uric acid nephrolithiasis can be reduced by the use of antiuricosuric drugs. One should also consider eating a low purine diet. Additionally, making the urine pH more alkaline is protective.[4]
References
^"Hyperuricosuria and Gouty Diathesis". Medscape, WebMD Ltd. 2016. Retrieved 1 April 2013.
^"Allopurinol". MedlinePlus, National Library of Medicine, US National Institutes of Health. 2016. Retrieved 24 December 2016.
^"Nephrolithiasis". The Lecturio Medical Concept Library. Retrieved 11 August 2021.
^Mattle D, Hess B (May 2005). "Preventive treatment of nephrolithiasis with alkali citrate--a critical review" (PDF). Urol. Res. 33 (2): 73–9. doi:10.1007/s00240-005-0464-8. PMID 15875173.
External links
This article about a disease of the genitourinary system is a stub. You can help Wikipedia by expanding it.
hyperuricosuria, medical, term, referring, presence, excessive, amounts, uric, acid, urine, this, rate, greater, than, women, notable, direct, causes, hyperuricosuria, dissolution, uric, acid, crystals, kidneys, urinary, bladder, hyperuricemia, notable, indire. Hyperuricosuria is a medical term referring to the presence of excessive amounts of uric acid in the urine For men this is at a rate greater than 800 mg day and for women 750 mg day 1 Notable direct causes of hyperuricosuria are dissolution of uric acid crystals in the kidneys or urinary bladder and hyperuricemia Notable indirect causes include uricosuric drugs rapid breakdown of bodily tissues containing large quantities of DNA and RNA and a diet high in purine HyperuricosuriaUric acidSpecialtyNephrology urologyMedications that may contribute to the cure or amelioration of hyperuricosuria include allopurinol which acts by inhibiting xanthine oxidase and reducing uric acid production 2 Hyperuricosuria may be a medical sign of Gout very common Kidney stones of uric acid uric acid nephrolithiasis Acute uric acid nephropathy Acute kidney failure Tumor lysis syndrome Fanconi syndrome Dent s disease very rare Contents 1 Classification 2 Treatment 3 References 4 External linksClassification EditAcute hyperuricosuria is a common complication of tumor lysis syndrome This syndrome appears not to contribute to gout and to uric acid nephrolithiasis which is evidence that these two conditions have chronic not acute causes Chronic hyperuricosuria is associated with gout and uric acid nephrolithiasis 3 However both conditions can occur in the absence of hyperuricosuria Treatment of gout with uricosuric drugs can lead to uric acid nephrolithiasis Treatment EditIf neither hyperuricemia nor gout is present then the risk of uric acid nephrolithiasis can be reduced by the use of antiuricosuric drugs One should also consider eating a low purine diet Additionally making the urine pH more alkaline is protective 4 References Edit Hyperuricosuria and Gouty Diathesis Medscape WebMD Ltd 2016 Retrieved 1 April 2013 Allopurinol MedlinePlus National Library of Medicine US National Institutes of Health 2016 Retrieved 24 December 2016 Nephrolithiasis The Lecturio Medical Concept Library Retrieved 11 August 2021 Mattle D Hess B May 2005 Preventive treatment of nephrolithiasis with alkali citrate a critical review PDF Urol Res 33 2 73 9 doi 10 1007 s00240 005 0464 8 PMID 15875173 External links EditThis article about a disease of the genitourinary system is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Hyperuricosuria amp oldid 1038262288, wikipedia, wiki, book, books, library,
