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Histoplasma

Histoplasma is a genus of fungi in the order Onygenales.[1] Species are known human pathogens producing yeast-like states under pathogenic conditions. They are the causative agents of histoplasmosis in humans and epizootic lymphangitis in horses.[2]

Histoplasma
Tuberculate macroconidia of Histoplasma capsulatum
Scientific classification
Domain: Eukaryota
Kingdom: Fungi
Division: Ascomycota
Class: Eurotiomycetes
Order: Onygenales
Family: Ajellomycetaceae
Genus: Histoplasma
Darling (1906)
Type species
Histoplasma capsulatum
Darling (1906)
Species

Histoplasma capsulatum
Histoplasma duboisii
Histoplasma mississippiense (nom. inval.)
Histoplasma ohiense (nom. inval.)
Histoplasma suramericanum (nom. inval.)

Forms and stages edit

Histoplasma species have two forms: their environmental form is hyphal with microconidia and tuberculate macroconidia while their pathogenic form is a small intracellular yeast with a narrow neck and no bud with no capsule.[3] Infection occurs through inhalation of microconidia or small mycelial fragments. The dimorphic mold-yeast transforms and enters host macrophages and proliferates within them. Infections are most often seen in immunodeficient individuals.[4]

Species are mainly found in the Ohio and Mississippi River Valleys in the United States (H.ohiense and H. mississippiense) as well as Central (H. capsulatum) and South America (H. suramericanum), Africa (H. duboisii), Asia, and Australia.[5][6]

References edit

  1. ^ Jiang Y, Dukik K, Munoz JF, Sigler L, Schwartz IS, Govender NP, Kenyon C, Feng P, van den Ende BG, Stielow JB, Stchigel AM, Lu H, de Hoog S (2018). "Phylogeny, ecology and taxonomy of systemic pathogens and their relatives in Ajellomycetaceae (Onygenales): Blastomyces, Emergomyces, Emmonsia, Emmonsiellopsis". Fungal Diversity. 90: 245–291. doi:10.1007/s13225-018-0403-y. hdl:10067/1520590151162165141.
  2. ^ OIE Manual of Diagnostic Tests and Vaccines for Terrestrial Animals 2004 Chapter 2.5.13, . Archived from the original on 2007-08-04. Retrieved 2007-06-14.{{cite web}}: CS1 maint: archived copy as title (link)
  3. ^ Hutton, JP (April 1985). "Hyphal forms of Histoplasma capsulatum. A common manifestation of intravascular infections". Archives of Pathology and Laboratory Medicine. 109 (4): 330–332. PMID 3885898 – via Pubmed.
  4. ^ Lopez, CE (Oct 2006). "Dimorphism and pathogenesis of Histoplasma capsulatum". Revista Argentina de Microbiologia. 38 (4): 235–242. PMID 17370580 – via Pubmed.
  5. ^ "Histoplasmosis". Centers for Disease Control and Prevention. 28 October 2020. Retrieved 27 January 2021.
  6. ^ Sepúlveda VE, Márquez R, Turissini DA, Goldman WE, Matute DR (2017). "Genome sequences reveal cryptic speciation in the human pathogen Histoplasma capsulatum". mBio. 8 (6). doi:10.1128/mbio.01339-17. PMC 5717386.



histoplasma, genus, fungi, order, onygenales, species, known, human, pathogens, producing, yeast, like, states, under, pathogenic, conditions, they, causative, agents, histoplasmosis, humans, epizootic, lymphangitis, horses, tuberculate, macroconidia, capsulat. Histoplasma is a genus of fungi in the order Onygenales 1 Species are known human pathogens producing yeast like states under pathogenic conditions They are the causative agents of histoplasmosis in humans and epizootic lymphangitis in horses 2 HistoplasmaTuberculate macroconidia of Histoplasma capsulatumScientific classificationDomain EukaryotaKingdom FungiDivision AscomycotaClass EurotiomycetesOrder OnygenalesFamily AjellomycetaceaeGenus HistoplasmaDarling 1906 Type speciesHistoplasma capsulatumDarling 1906 SpeciesHistoplasma capsulatumHistoplasma duboisiiHistoplasma mississippiense nom inval Histoplasma ohiense nom inval Histoplasma suramericanum nom inval Forms and stages editHistoplasma species have two forms their environmental form is hyphal with microconidia and tuberculate macroconidia while their pathogenic form is a small intracellular yeast with a narrow neck and no bud with no capsule 3 Infection occurs through inhalation of microconidia or small mycelial fragments The dimorphic mold yeast transforms and enters host macrophages and proliferates within them Infections are most often seen in immunodeficient individuals 4 Species are mainly found in the Ohio and Mississippi River Valleys in the United States H ohiense and H mississippiense as well as Central H capsulatum and South America H suramericanum Africa H duboisii Asia and Australia 5 6 References edit Jiang Y Dukik K Munoz JF Sigler L Schwartz IS Govender NP Kenyon C Feng P van den Ende BG Stielow JB Stchigel AM Lu H de Hoog S 2018 Phylogeny ecology and taxonomy of systemic pathogens and their relatives in Ajellomycetaceae Onygenales Blastomyces Emergomyces Emmonsia Emmonsiellopsis Fungal Diversity 90 245 291 doi 10 1007 s13225 018 0403 y hdl 10067 1520590151162165141 OIE Manual of Diagnostic Tests and Vaccines for Terrestrial Animals 2004 Chapter 2 5 13 Archived copy Archived from the original on 2007 08 04 Retrieved 2007 06 14 a href Template Cite web html title Template Cite web cite web a CS1 maint archived copy as title link Hutton JP April 1985 Hyphal forms of Histoplasma capsulatum A common manifestation of intravascular infections Archives of Pathology and Laboratory Medicine 109 4 330 332 PMID 3885898 via Pubmed Lopez CE Oct 2006 Dimorphism and pathogenesis of Histoplasma capsulatum Revista Argentina de Microbiologia 38 4 235 242 PMID 17370580 via Pubmed Histoplasmosis Centers for Disease Control and Prevention 28 October 2020 Retrieved 27 January 2021 Sepulveda VE Marquez R Turissini DA Goldman WE Matute DR 2017 Genome sequences reveal cryptic speciation in the human pathogen Histoplasma capsulatum mBio 8 6 doi 10 1128 mbio 01339 17 PMC 5717386 nbsp This Ascomycota related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Histoplasma amp oldid 1205179525, wikipedia, wiki, book, books, library,

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