guanosine 3′,5′-bis(diphosphate) + H2O GDP + diphosphate
This enzyme belongs to the family of hydrolases, specifically those acting on diphosphoric monoester bonds. The systematic name is guanosine-3′,5′-bis(diphosphate) 3′-diphosphohydrolase. Other names in common use include guanosine-3′,5′-bis(diphosphate) 3′-pyrophosphatase, PpGpp-3'-pyrophosphohydrolase, and PpGpp phosphohydrolase. This enzyme participates in purine metabolism.
Structural studiesedit
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1VJ7.
Referencesedit
^Heinemeyer EA, Richter D (1978). "Characterization of the guanosine 5'-triphosphate 3′-diphosphate and guanosine 5′-diphosphate 3′-diphosphate degradation reaction catalyzed by a specific pyrophosphorylase from Escherichia coli". Biochemistry. 17 (25): 5368–72. doi:10.1021/bi00618a007. PMID 365225.
^Richter D, Fehr S, Harder R (1979). "The guanosine 3′,5′-bis(diphosphate) (ppGpp) cycle. Comparison of synthesis and degradation of guanosine 3′,5′-bis(diphosphate) in various bacterial systems". Eur. J. Biochem. 99 (1): 57–64. doi:10.1111/j.1432-1033.1979.tb13230.x. PMID 114395.
guanosine, diphosphate, diphosphatase, enzyme, guanosine, diphosphate, diphosphatase, catalyzes, reactionguanosine, diphosphate, diphosphataseidentifiersec, 2cas, 70457, 4databasesintenzintenz, viewbrendabrenda, entryexpasynicezyme, viewkeggkegg, entrymetacycm. The enzyme guanosine 3 5 bis diphosphate 3 diphosphatase EC 3 1 7 2 1 2 catalyzes the reactionguanosine 3 5 bis diphosphate 3 diphosphataseIdentifiersEC no 3 1 7 2CAS no 70457 12 4DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumGene OntologyAmiGO QuickGOSearchPMCarticlesPubMedarticlesNCBIproteins guanosine 3 5 bis diphosphate H2O displaystyle rightleftharpoons GDP diphosphate This enzyme belongs to the family of hydrolases specifically those acting on diphosphoric monoester bonds The systematic name is guanosine 3 5 bis diphosphate 3 diphosphohydrolase Other names in common use include guanosine 3 5 bis diphosphate 3 pyrophosphatase PpGpp 3 pyrophosphohydrolase and PpGpp phosphohydrolase This enzyme participates in purine metabolism Structural studies editAs of late 2007 only one structure has been solved for this class of enzymes with the PDB accession code 1VJ7 References edit Heinemeyer EA Richter D 1978 Characterization of the guanosine 5 triphosphate 3 diphosphate and guanosine 5 diphosphate 3 diphosphate degradation reaction catalyzed by a specific pyrophosphorylase from Escherichia coli Biochemistry 17 25 5368 72 doi 10 1021 bi00618a007 PMID 365225 Richter D Fehr S Harder R 1979 The guanosine 3 5 bis diphosphate ppGpp cycle Comparison of synthesis and degradation of guanosine 3 5 bis diphosphate in various bacterial systems Eur J Biochem 99 1 57 64 doi 10 1111 j 1432 1033 1979 tb13230 x PMID 114395 Portal nbsp Biology This EC 3 1 enzyme related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Guanosine 3 27 5 27 bis diphosphate 3 27 diphosphatase amp oldid 1172349379, wikipedia, wiki, book, books, library,
