growth, factor, like, domain, growth, factor, like, domain, gfld, protein, domain, structurally, related, epidermal, growth, factor, which, high, binding, affinity, epidermal, growth, factor, receptor, structural, domains, within, larger, proteins, gfld, regio. A growth factor like domain GFLD is a protein domain structurally related to epidermal growth factor which has a high binding affinity for the epidermal growth factor receptor As structural domains within larger proteins GFLD regions commonly bind calcium ions A subtype present in the N terminal region of the amyloid precursor protein is a member of the heparin binding class of GFLDs and may itself have growth factor function particularly in promoting neuronal development Amyloid precursor N terminalThe GFLD region of amyloid precursor proteinIdentifiersSymbolAPP CU bdPfamPF02177InterProIPR008154SMARTSM00006SCOP21mwp SCOPe SUPFAMAvailable protein structures Pfam structures ECOD PDBRCSB PDB PDBe PDBjPDBsumstructure summaryPDB1mwp 1owt 2fjz 2fk1 2fk2 2fk3 2fkl 2fma References editRossjohn J Cappai R Feil SC Henry A McKinstry WJ Galatis D Hesse L Multhaup G Beyreuther K Masters CL Parker MW April 1999 Crystal structure of the N terminal growth factor like domain of Alzheimer amyloid precursor protein Nature Structural Biology 6 4 327 31 doi 10 1038 7562 PMID 10201399 S2CID 30925432 nbsp This protein related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Growth factor like domain amp oldid 977931564, wikipedia, wiki, book, books, library,
