As the fumonisins appear to be non-genotoxic the possibility that they belong to another class of non-genotoxic carcinogens, the peroxisome proliferators, was investigated[3]
Genetic engineering is reported as a promising means of detoxifying mycotoxins. This approach may provide innovative solutions to the problem of fumonisin in corn.[4]
At least 15 different fumonisins have so far been reported and other minor metabolites have been identified, although most of them have not been shown to occur naturally.[5] In 2015, a unique class of non-aminated fumonisins[6] was reported on grapes infected with Aspergillus welwitschiae, although their toxicities have not yet been established.
Other Fusarium toxinsedit
The trichothecene (T-2) mycotoxins are a group of over 40 compounds produced by fungi of the genus Fusarium, a common grain mold.[7]
The estrogenic metabolite, zearalenone, is also referred to as F-2 toxin.[8]
^Gelderblom, Wentzel C. A.; Marasas, Walter F. O.; Vleggaar, R.; Thiel, Pieter G.; Cawood, M. E. (February 1992). "Fumonisins: Isolation, chemical characterization and biological effects". Mycopathologia. 117 (1–2): 11–16. doi:10.1007/BF00497273. PMID 1513367. S2CID 12066786.
^Jackson, Lauren S.; Jonathan W. DeVries; Lloyd B. Bullerman (1996). Fumonisins In Food. New York, NY: Plenum Press. p. 289. ISBN0-306-45216-2.
^Igawa, T; Takahashi-Ando, N; Ochiai, N; Ohsato, S; Shimizu, T; Kudo, T; Yamaguchi, I; Kimura, M (March 2007). "Reduced contamination by the Fusarium mycotoxin zearalenone in maize kernels through genetic modification with a detoxification gene". Appl Environ Microbiol. 73 (5): 1622–9. Bibcode:2007ApEnM..73.1622I. doi:10.1128/aem.01077-06. PMC1828766. PMID 17209063.
^Marasas, W.F.O.; J.D. Miller; R.T. Riley; A. Visconti (2000). Environmental Health Criteria 219: Fumonisin B1. Vammala, Finland: World Health Organization. p. 9. ISBN92-4-157219-1.
^Renaud, J.B.R; M.J Kelman; Tianyu F. Qi; K.A. Seifert; M.W. Sumarah (2015). "Product ion filtering with rapid polarity switching for the detection of all fumonisins and AAL-toxins". Rapid Communications in Mass Spectrometry. Rapid Communications in Mass Spectrometry Volume 29, Issue 22, 30 November 2015, Pages 2131–2139. 29 (22): 2131–2139. Bibcode:2015RCMS...29.2131R. doi:10.1002/rcm.7374. PMID 26467225.
^USAMRIID's Medical Management of Biological Casualties Handbook, 6th Ed. McLean, VA: International Medical Publishing, Inc. 2005. pp. 102–103. ISBN1-58808-162-1.
^Marasas, W.F.O.; Paul E. Nelson (1987). Mycotoxicology: Introduction to the Mycology, Plant Pathology, Chemistry, Toxicology, and Pathology of Naturally Occurring Mycotoxicoses In Animals and Man. University Park, PA: The Pennsylvania State University Press. p. 47. ISBN0-271-00442-8.
This biochemistry article is a stub. You can help Wikipedia by expanding it.
fumonisin, fumonisins, group, mycotoxins, derived, from, fusarium, their, liseola, section, they, have, strong, structural, similarity, sphinganine, backbone, precursor, sphingolipids, chemical, structure, fumonisin, b1more, specifically, refer, b4as, fumonisi. The fumonisins are a group of mycotoxins derived from Fusarium and their Liseola section 1 They have strong structural similarity to sphinganine the backbone precursor of sphingolipids 2 Chemical structure of fumonisin B1More specifically it can refer to Fumonisin B1 Fumonisin B2 Fumonisin B3 Fumonisin B4As the fumonisins appear to be non genotoxic the possibility that they belong to another class of non genotoxic carcinogens the peroxisome proliferators was investigated 3 Genetic engineering is reported as a promising means of detoxifying mycotoxins This approach may provide innovative solutions to the problem of fumonisin in corn 4 At least 15 different fumonisins have so far been reported and other minor metabolites have been identified although most of them have not been shown to occur naturally 5 In 2015 a unique class of non aminated fumonisins 6 was reported on grapes infected with Aspergillus welwitschiae although their toxicities have not yet been established Other Fusarium toxins editThe trichothecene T 2 mycotoxins are a group of over 40 compounds produced by fungi of the genus Fusarium a common grain mold 7 The estrogenic metabolite zearalenone is also referred to as F 2 toxin 8 References edit Fumonisins at the U S National Library of Medicine Medical Subject Headings MeSH Gelderblom Wentzel C A Marasas Walter F O Vleggaar R Thiel Pieter G Cawood M E February 1992 Fumonisins Isolation chemical characterization and biological effects Mycopathologia 117 1 2 11 16 doi 10 1007 BF00497273 PMID 1513367 S2CID 12066786 Jackson Lauren S Jonathan W DeVries Lloyd B Bullerman 1996 Fumonisins In Food New York NY Plenum Press p 289 ISBN 0 306 45216 2 Igawa T Takahashi Ando N Ochiai N Ohsato S Shimizu T Kudo T Yamaguchi I Kimura M March 2007 Reduced contamination by the Fusarium mycotoxin zearalenone in maize kernels through genetic modification with a detoxification gene Appl Environ Microbiol 73 5 1622 9 Bibcode 2007ApEnM 73 1622I doi 10 1128 aem 01077 06 PMC 1828766 PMID 17209063 Marasas W F O J D Miller R T Riley A Visconti 2000 Environmental Health Criteria 219 Fumonisin B1 Vammala Finland World Health Organization p 9 ISBN 92 4 157219 1 Renaud J B R M J Kelman Tianyu F Qi K A Seifert M W Sumarah 2015 Product ion filtering with rapid polarity switching for the detection of all fumonisins and AAL toxins Rapid Communications in Mass Spectrometry Rapid Communications in Mass Spectrometry Volume 29 Issue 22 30 November 2015 Pages 2131 2139 29 22 2131 2139 Bibcode 2015RCMS 29 2131R doi 10 1002 rcm 7374 PMID 26467225 USAMRIID s Medical Management of Biological Casualties Handbook 6th Ed McLean VA International Medical Publishing Inc 2005 pp 102 103 ISBN 1 58808 162 1 Marasas W F O Paul E Nelson 1987 Mycotoxicology Introduction to the Mycology Plant Pathology Chemistry Toxicology and Pathology of Naturally Occurring Mycotoxicoses In Animals and Man University Park PA The Pennsylvania State University Press p 47 ISBN 0 271 00442 8 nbsp This biochemistry article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Fumonisin amp oldid 1184185506, wikipedia, wiki, book, books, library,
