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Frank DeStefano

August 25, 2023

Not to be confused with Frank De Stefano.

Frank DeStefano FACPM is a medical epidemiologist and researcher at the Centers for Disease Control and Prevention, where he is director of the Immunization Safety Office.

Education Edit

Frank DeStefano graduated from Cortland (NY) High School in 1970. DeStefano graduated from Cornell University in 1974, receiving a Bachelor of Science degree, and the University of Pittsburgh School of Medicine, from which he received a medical degree in 1978. He received his MPH at Johns Hopkins University School of Hygiene and Public Health in 1984.[1]

Research Edit

DeStefano is an author of a number of scientific studies concluding that vaccines, in particular thimerosal-containing ones, do not cause autism. In March 2013, for example, DeStefano was the lead author on a study in the Journal of Pediatrics, which concluded that exposure of children to particular ingredients in vaccines, namely proteins and polysaccharides, did not increase their risk of autism. In addition, DeStefano et al. concluded that children with autism had received the same number of antigens as children without.[2] This study received widespread media attention.[3][4][5]

As director of the ISO, his research focuses primarily on alleged and real adverse reactions to vaccines, and how common these reactions are. As mentioned above, some of DeStefano's research pertains to the use of thiomersal in vaccines; for example, he co-authored a study in 2003 in Pediatrics which concluded that there was no consistent association between thimerosal-containing vaccines and neurodevelopmental disorders.[6] In addition, he was the final author of a study on the alleged link between thimerosal and autism, authored by the Vaccine Safety Datalink team, published in the New England Journal of Medicine. This study concluded that "Our study does not support a causal association between early exposure to mercury from thimerosal-containing vaccines and immune globulins and deficits in neuropsychological functioning at the age of 7 to 10 years."[7] Other topics he has published research on include Guillain–Barré syndrome,[8] as well as the potential link between seizures and the whole-cell pertussis vaccine or MMR vaccine.[9] More generally, with regard to the VSD, he published a study in 2001 summarizing the ability of the project to reveal potential risks associated with vaccination, especially intussusception, through conduction of a population-based cohort study.[10]

Originally, however, DeStefano's research focused on the safety of contraceptives, a topic he researched from 1982 to 1984 as a medical officer at the National Institutes of Health.[11] Also in 1982, he joined the CDC as a senior epidemiologist in the Agent Orange projects.

Career Edit

After completing a residency in pediatrics at the University of Rochester School of Medicine, he joined the Epidemic Intelligence Service in 1979. In 1982, he completed a CDC residency in preventive medicine. In 2004, DeStefano was appointed acting chief of the Immunization Safety Branch of the National Immunization Program, now known as the National Center for Immunization and Respiratory Diseases. From 1992 to 1996, DeStefano held a post at the Marshfield Medical Research Foundation in Marshfield, Wisconsin. In 1996, he returned to the CDC.[12]

Selected publications Edit

  • Kramarz, Piotr; France, Eric (2001). "Population-based study of rotavirus vaccination and intussusception". Pediatric Infectious Disease Journal. 20 (4): 410–416. doi:10.1097/00006454-200104000-00008. PMID 11332666. S2CID 23664999.
  • Bohlke, K.; Davis, R. L.; Marcy, S. M.; et al. (2003). "Risk of Anaphylaxis After Vaccination of Children and Adolescents". Pediatrics. 112 (4): 815–820. doi:10.1542/peds.112.4.815. PMID 14523172.
  • Varricchio, F.; Iskander, J.; Destefano, F.; Ball, R.; Pless, R.; Braun, M. M.; Chen, R. T. (2004). "Understanding vaccine safety information from the Vaccine Adverse Event Reporting System". The Pediatric Infectious Disease Journal. 23 (4): 287–294. doi:10.1097/00006454-200404000-00002. PMID 15071280.

References Edit

  1. ^ "Frank DeStefano MD MPH". WebMD. Retrieved 14 August 2013.
  2. ^ "The Risk of Autism Is Not Increased by "Too Many Vaccines Too Soon"". Journal of Pediatrics. 29 March 2013. Retrieved 14 August 2013.
  3. ^ "Vaccine-autism connection debunked again". CNN. 29 March 2013. Retrieved 11 September 2013.
  4. ^ Trotter, J. K. (29 March 2013). "Nope, Vaccinations Don't Cause Autism". The Atlantic Wire. Retrieved 11 September 2013.
  5. ^ Hamilton, Jon (29 March 2013). "Number Of Early Childhood Vaccines Not Linked To Autism". NPR.org. NPR. Retrieved 11 September 2013.
  6. ^ Verstraeten, Thomas (November 2003). "Safety of Thimerosal-Containing Vaccines: A Two-Phased Study of Computerized Health Maintenance Organization Databases". Pediatrics. 112 (5): 1039–1048. doi:10.1542/peds.112.2.e98. PMID 14595043.
  7. ^ Thompson, W. W.; Price, C.; Goodson, B.; Shay, D. K.; Benson, P.; Hinrichsen, V. L.; Lewis, E.; Eriksen, E.; Ray, P.; Marcy, S. M.; Dunn, J.; Jackson, L. A.; Lieu, T. A.; Black, S.; Stewart, G.; Weintraub, E. S.; Davis, R. L.; Destefano, F.; Vaccine Safety Datalink, T. (2007). "Early Thimerosal Exposure and Neuropsychological Outcomes at 7 to 10 Years". New England Journal of Medicine. 357 (13): 1281–1292. doi:10.1056/NEJMoa071434. PMID 17898097.
  8. ^ Haber, P.; Destefano, F.; Angulo, F. J.; Iskander, J.; Shadomy, S. V.; Weintraub, E.; Chen, R. T. (2004). "Guillain–Barré Syndrome Following Influenza Vaccination". JAMA. 292 (20): 2478–2481. doi:10.1001/jama.292.20.2478. PMID 15562126.
  9. ^ Barlow, W. E.; Davis, R. L.; Glasser, J. W.; Rhodes, P. H.; Thompson, R. S.; Mullooly, J. P.; Black, S. B.; Shinefield, H. R.; Ward, J. I.; Marcy, S. M.; Destefano, F.; Chen, V.; Immanuel, J. A.; Pearson, C. M.; Vadheim, V.; Rebolledo, D.; Christakis, P. J.; Benson, N.; Lewis, R. T.; Centers for Disease Control Prevention Vaccine Safety Datalink Working Group (2001). "The Risk of Seizures after Receipt of Whole-Cell Pertussis or Measles, Mumps, and Rubella Vaccine". New England Journal of Medicine. 345 (9): 656–661. doi:10.1056/NEJMoa003077. PMID 11547719.
  10. ^ Destefano, F.; Vaccine Safety Datalink Research Group (2001). "The Vaccine Safety Datalink project". Pharmacoepidemiology and Drug Safety. 10 (5): 403–406. doi:10.1002/pds.613. PMID 11802585. S2CID 20854409.
  11. ^ Ory, H. W.; Rubin, G. L.; Jones, V.; et al. (1984). "Mortality among young black women using contraceptives". JAMA: The Journal of the American Medical Association. 251 (8): 1044–1048. doi:10.1001/jama.1984.03340320030022. PMID 6229648.
  12. ^ "NCIRD Milestones". National Center for Immunization and Respiratory Diseases. September 2006. Archived from the original on 2013-08-15. Retrieved 15 August 2013.

August 25, 2023
frank, destefano, confused, with, frank, stefano, facpm, medical, epidemiologist, researcher, centers, disease, control, prevention, where, director, immunization, safety, office, contents, education, research, career, selected, publications, referenceseducati. Not to be confused with Frank De Stefano Frank DeStefano FACPM is a medical epidemiologist and researcher at the Centers for Disease Control and Prevention where he is director of the Immunization Safety Office Contents 1 Education 2 Research 3 Career 4 Selected publications 5 ReferencesEducation EditFrank DeStefano graduated from Cortland NY High School in 1970 DeStefano graduated from Cornell University in 1974 receiving a Bachelor of Science degree and the University of Pittsburgh School of Medicine from which he received a medical degree in 1978 He received his MPH at Johns Hopkins University School of Hygiene and Public Health in 1984 1 Research EditDeStefano is an author of a number of scientific studies concluding that vaccines in particular thimerosal containing ones do not cause autism In March 2013 for example DeStefano was the lead author on a study in the Journal of Pediatrics which concluded that exposure of children to particular ingredients in vaccines namely proteins and polysaccharides did not increase their risk of autism In addition DeStefano et al concluded that children with autism had received the same number of antigens as children without 2 This study received widespread media attention 3 4 5 As director of the ISO his research focuses primarily on alleged and real adverse reactions to vaccines and how common these reactions are As mentioned above some of DeStefano s research pertains to the use of thiomersal in vaccines for example he co authored a study in 2003 in Pediatrics which concluded that there was no consistent association between thimerosal containing vaccines and neurodevelopmental disorders 6 In addition he was the final author of a study on the alleged link between thimerosal and autism authored by the Vaccine Safety Datalink team published in the New England Journal of Medicine This study concluded that Our study does not support a causal association between early exposure to mercury from thimerosal containing vaccines and immune globulins and deficits in neuropsychological functioning at the age of 7 to 10 years 7 Other topics he has published research on include Guillain Barre syndrome 8 as well as the potential link between seizures and the whole cell pertussis vaccine or MMR vaccine 9 More generally with regard to the VSD he published a study in 2001 summarizing the ability of the project to reveal potential risks associated with vaccination especially intussusception through conduction of a population based cohort study 10 Originally however DeStefano s research focused on the safety of contraceptives a topic he researched from 1982 to 1984 as a medical officer at the National Institutes of Health 11 Also in 1982 he joined the CDC as a senior epidemiologist in the Agent Orange projects Career EditAfter completing a residency in pediatrics at the University of Rochester School of Medicine he joined the Epidemic Intelligence Service in 1979 In 1982 he completed a CDC residency in preventive medicine In 2004 DeStefano was appointed acting chief of the Immunization Safety Branch of the National Immunization Program now known as the National Center for Immunization and Respiratory Diseases From 1992 to 1996 DeStefano held a post at the Marshfield Medical Research Foundation in Marshfield Wisconsin In 1996 he returned to the CDC 12 Selected publications EditKramarz Piotr France Eric 2001 Population based study of rotavirus vaccination and intussusception Pediatric Infectious Disease Journal 20 4 410 416 doi 10 1097 00006454 200104000 00008 PMID 11332666 S2CID 23664999 Bohlke K Davis R L Marcy S M et al 2003 Risk of Anaphylaxis After Vaccination of Children and Adolescents Pediatrics 112 4 815 820 doi 10 1542 peds 112 4 815 PMID 14523172 Varricchio F Iskander J Destefano F Ball R Pless R Braun M M Chen R T 2004 Understanding vaccine safety information from the Vaccine Adverse Event Reporting System The Pediatric Infectious Disease Journal 23 4 287 294 doi 10 1097 00006454 200404000 00002 PMID 15071280 References Edit Frank DeStefano MD MPH WebMD Retrieved 14 August 2013 The Risk of Autism Is Not Increased by Too Many Vaccines Too Soon Journal of Pediatrics 29 March 2013 Retrieved 14 August 2013 Vaccine autism connection debunked again CNN 29 March 2013 Retrieved 11 September 2013 Trotter J K 29 March 2013 Nope Vaccinations Don t Cause Autism The Atlantic Wire Retrieved 11 September 2013 Hamilton Jon 29 March 2013 Number Of Early Childhood Vaccines Not Linked To Autism NPR org NPR Retrieved 11 September 2013 Verstraeten Thomas November 2003 Safety of Thimerosal Containing Vaccines A Two Phased Study of Computerized Health Maintenance Organization Databases Pediatrics 112 5 1039 1048 doi 10 1542 peds 112 2 e98 PMID 14595043 Thompson W W Price C Goodson B Shay D K Benson P Hinrichsen V L Lewis E Eriksen E Ray P Marcy S M Dunn J Jackson L A Lieu T A Black S Stewart G Weintraub E S Davis R L Destefano F Vaccine Safety Datalink T 2007 Early Thimerosal Exposure and Neuropsychological Outcomes at 7 to 10 Years New England Journal of Medicine 357 13 1281 1292 doi 10 1056 NEJMoa071434 PMID 17898097 Haber P Destefano F Angulo F J Iskander J Shadomy S V Weintraub E Chen R T 2004 Guillain Barre Syndrome Following Influenza Vaccination JAMA 292 20 2478 2481 doi 10 1001 jama 292 20 2478 PMID 15562126 Barlow W E Davis R L Glasser J W Rhodes P H Thompson R S Mullooly J P Black S B Shinefield H R Ward J I Marcy S M Destefano F Chen V Immanuel J A Pearson C M Vadheim V Rebolledo D Christakis P J Benson N Lewis R T Centers for Disease Control Prevention Vaccine Safety Datalink Working Group 2001 The Risk of Seizures after Receipt of Whole Cell Pertussis or Measles Mumps and Rubella Vaccine New England Journal of Medicine 345 9 656 661 doi 10 1056 NEJMoa003077 PMID 11547719 Destefano F Vaccine Safety Datalink Research Group 2001 The Vaccine Safety Datalink project Pharmacoepidemiology and Drug Safety 10 5 403 406 doi 10 1002 pds 613 PMID 11802585 S2CID 20854409 Ory H W Rubin G L Jones V et al 1984 Mortality among young black women using contraceptives JAMA The Journal of the American Medical Association 251 8 1044 1048 doi 10 1001 jama 1984 03340320030022 PMID 6229648 NCIRD Milestones National Center for Immunization and Respiratory Diseases September 2006 Archived from the original on 2013 08 15 Retrieved 15 August 2013 Retrieved from https en wikipedia org w index php title Frank DeStefano amp oldid 1171072695, wikipedia, wiki, book, books, library,

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