Flavokavain A is a flavokavain found in the kava plant.[1] It induces apoptosis in bladder cancer cells via a Bax protein-dependent and mitochondria-dependent apoptotic pathway.[2]
^Dharmaratne, H. Ranjith W.; N. P. Dhammika Nanayakkara; Ikhlas A. Khan (February 2002). "Kavalactones from Piper methysticum, and their 13C NMR spectroscopic analyses". Phytochemistry. 59 (4): 429–33. doi:10.1016/S0031-9422(01)00443-5. PMID 11830162.
^Zi X, Simoneau AR (April 2005). "Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice" (PDF). Cancer Research. 65 (8): 3479–86. doi:10.1158/0008-5472.CAN-04-3803. PMID 15833884.
flavokavain, flavokavain, found, kava, plant, induces, apoptosis, bladder, cancer, cells, protein, dependent, mitochondria, dependent, apoptotic, pathway, namespreferred, iupac, name, hydroxy, trimethoxychalconeother, names, flavokawain, aidentifierscas, numbe. Flavokavain A is a flavokavain found in the kava plant 1 It induces apoptosis in bladder cancer cells via a Bax protein dependent and mitochondria dependent apoptotic pathway 2 Flavokavain A NamesPreferred IUPAC name 2 Hydroxy 4 4 6 trimethoxychalconeOther names Flavokawain AIdentifiersCAS Number 37951 13 6 Y3D model JSmol Interactive imageBeilstein Reference 2224776PubChem CID 5355469UNII 8OM2XZ2ZM3 YSMILES O C C2 C O C C OC C C2OC C C C1 CC C OC C C1PropertiesChemical formula C 18H 18O 5Molar mass 314 337 g mol 1Except where otherwise noted data are given for materials in their standard state at 25 C 77 F 100 kPa Y verify what is Y N Infobox references Flavokavains A and B enhance hepatotoxicity of paracetamol underscoring a potentially serious interaction between paracetamol and kava See also editKavalactoneReferences edit Dharmaratne H Ranjith W N P Dhammika Nanayakkara Ikhlas A Khan February 2002 Kavalactones from Piper methysticum and their 13C NMR spectroscopic analyses Phytochemistry 59 4 429 33 doi 10 1016 S0031 9422 01 00443 5 PMID 11830162 Zi X Simoneau AR April 2005 Flavokawain A a novel chalcone from kava extract induces apoptosis in bladder cancer cells by involvement of Bax protein dependent and mitochondria dependent apoptotic pathway and suppresses tumor growth in mice PDF Cancer Research 65 8 3479 86 doi 10 1158 0008 5472 CAN 04 3803 PMID 15833884 External links editFlavokawain A at the United States National Library of Medicine nbsp This article about an aromatic compound is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Flavokavain A amp oldid 1192283168, wikipedia, wiki, book, books, library,
