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Fibrous cap

The fibrous cap is a layer of fibrous connective tissue, which is thicker and less cellular than the normal intima, found in atherosclerotic plaques. The fibrous cap contains macrophages and smooth muscle cells.[1] The fibrous cap of an atheroma is composed of bundles of muscle cells, macrophages, foam cells, lymphocytes, collagen and elastin.[1]

The fibrous cap is prone to rupture and ulceration which can lead to thrombosis. In advanced lesions, further complications may arise including calcification of the fibrous cap.[2]

References edit

  1. ^ a b Hansson, Göran K.; Libby, Peter (July 2006). "The immune response in atherosclerosis: a double-edged sword". Nature Reviews Immunology. 6 (7): 508–519. doi:10.1038/nri1882. PMID 16778830.
  2. ^ Swirski, F. K.; Nahrendorf, M. (10 January 2013). "Leukocyte Behavior in Atherosclerosis, Myocardial Infarction, and Heart Failure". Science. 339 (6116): 161–166. doi:10.1126/science.1230719. PMC 3891792. PMID 23307733.


fibrous, fibrous, layer, fibrous, connective, tissue, which, thicker, less, cellular, than, normal, intima, found, atherosclerotic, plaques, fibrous, contains, macrophages, smooth, muscle, cells, fibrous, atheroma, composed, bundles, muscle, cells, macrophages. The fibrous cap is a layer of fibrous connective tissue which is thicker and less cellular than the normal intima found in atherosclerotic plaques The fibrous cap contains macrophages and smooth muscle cells 1 The fibrous cap of an atheroma is composed of bundles of muscle cells macrophages foam cells lymphocytes collagen and elastin 1 The fibrous cap is prone to rupture and ulceration which can lead to thrombosis In advanced lesions further complications may arise including calcification of the fibrous cap 2 References edit a b Hansson Goran K Libby Peter July 2006 The immune response in atherosclerosis a double edged sword Nature Reviews Immunology 6 7 508 519 doi 10 1038 nri1882 PMID 16778830 Swirski F K Nahrendorf M 10 January 2013 Leukocyte Behavior in Atherosclerosis Myocardial Infarction and Heart Failure Science 339 6116 161 166 doi 10 1126 science 1230719 PMC 3891792 PMID 23307733 nbsp This cardiovascular system article is a stub You can help Wikipedia by expanding it vte nbsp This article related to pathology is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Fibrous cap amp oldid 1090490321, wikipedia, wiki, book, books, library,

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