Members of the F-box protein family, such as FBXO28, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004).[supplied by OMIM][6]
Referencesedit
^ abcGRCh38: Ensembl release 89: ENSG00000143756 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000047539 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Seki N, Ohira M, Nagase T, Ishikawa K, Miyajima N, Nakajima D, Nomura N, Ohara O (Feb 1998). "Characterization of cDNA clones in size-fractionated cDNA libraries from human brain". DNA Res. 4 (5): 345–9. doi:10.1093/dnares/4.5.345. PMID 9455484.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Jin J, Cardozo T, Lovering RC, et al. (2005). "Systematic analysis and nomenclature of mammalian F-box proteins". Genes Dev. 18 (21): 2573–80. doi:10.1101/gad.1255304. PMC525538. PMID 15520277.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC139241. PMID 12477932.
January 01, 1970
fbxo28, only, protein, protein, that, humans, encoded, gene, identifiersaliases, cenp, fbx28, protein, dee100external, idsomim, 609100, 1261890, homologene, 9050, genecards, gene, location, human, chromosome, human, band1q42, 11start224, end224, gene, location. F box only protein 28 is a protein that in humans is encoded by the FBXO28 gene 5 6 FBXO28IdentifiersAliasesFBXO28 CENP 30 Fbx28 F box protein 28 DEE100External IDsOMIM 609100 MGI 1261890 HomoloGene 9050 GeneCards FBXO28Gene location Human Chr Chromosome 1 human 1 Band1q42 11Start224 114 111 bp 1 End224 162 047 bp 1 Gene location Mouse Chr Chromosome 1 mouse 2 Band1 H5 1 84 93 cMStart182 140 667 bp 2 End182 169 194 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed inhair follicleendothelial cellkidney tubuleAchilles tendonBrodmann area 23tibiagerminal epitheliummiddle temporal gyrusvulvavisceral pleuraTop expressed insecondary oocyteexternal carotid arteryinternal carotid arterylacrimal glandsubmandibular glandmotor neuronparotid glandretinal pigment epitheliummedial ganglionic eminenceirisMore reference expression dataBioGPSMore reference expression dataOrthologsSpeciesHumanMouseEntrez2321967948EnsemblENSG00000143756ENSMUSG00000047539UniProtQ9NVF7Q8BIG4RefSeq mRNA NM 001136115NM 015176NM 175127RefSeq protein NP 001129587NP 055991NP 780336Location UCSC Chr 1 224 11 224 16 MbChr 1 182 14 182 17 MbPubMed search 3 4 WikidataView Edit HumanView Edit Mouse Members of the F box protein family such as FBXO28 are characterized by an approximately 40 amino acid F box motif SCF complexes formed by SKP1 MIM 601434 cullin see CUL1 MIM 603134 and F box proteins act as protein ubiquitin ligases F box proteins interact with SKP1 through the F box and they interact with ubiquitination targets through other protein interaction domains Jin et al 2004 supplied by OMIM 6 References edit a b c GRCh38 Ensembl release 89 ENSG00000143756 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000047539 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Seki N Ohira M Nagase T Ishikawa K Miyajima N Nakajima D Nomura N Ohara O Feb 1998 Characterization of cDNA clones in size fractionated cDNA libraries from human brain DNA Res 4 5 345 9 doi 10 1093 dnares 4 5 345 PMID 9455484 a b Entrez Gene FBXO28 F box protein 28 Further reading editOlsen JV Blagoev B Gnad F et al 2006 Global in vivo and site specific phosphorylation dynamics in signaling networks Cell 127 3 635 48 doi 10 1016 j cell 2006 09 026 PMID 17081983 S2CID 7827573 Gregory SG Barlow KF McLay KE et al 2006 The DNA sequence and biological annotation of human chromosome 1 Nature 441 7091 315 21 Bibcode 2006Natur 441 315G doi 10 1038 nature04727 PMID 16710414 Rual JF Venkatesan K Hao T et al 2005 Towards a proteome scale map of the human protein protein interaction network Nature 437 7062 1173 8 Bibcode 2005Natur 437 1173R doi 10 1038 nature04209 PMID 16189514 S2CID 4427026 Jin J Cardozo T Lovering RC et al 2005 Systematic analysis and nomenclature of mammalian F box proteins Genes Dev 18 21 2573 80 doi 10 1101 gad 1255304 PMC 525538 PMID 15520277 Gerhard DS Wagner L Feingold EA et al 2004 The Status Quality and Expansion of the NIH Full Length cDNA Project The Mammalian Gene Collection MGC Genome Res 14 10B 2121 7 doi 10 1101 gr 2596504 PMC 528928 PMID 15489334 Ota T Suzuki Y Nishikawa T et al 2004 Complete sequencing and characterization of 21 243 full length human cDNAs Nat Genet 36 1 40 5 doi 10 1038 ng1285 PMID 14702039 Strausberg RL Feingold EA Grouse LH et al 2003 Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 99 26 16899 903 Bibcode 2002PNAS 9916899M doi 10 1073 pnas 242603899 PMC 139241 PMID 12477932 Retrieved from https en wikipedia org w index php title FBXO28 amp oldid 1142681239, wikipedia, wiki, book, books, library,
