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Enthesitis

Enthesitis is inflammation of the entheses, the sites where tendons or ligaments insert into the bone.[1][2] It is an enthesopathy, a pathologic condition of the entheses. Early clinical manifestations are an aching sensation akin to "working out too much", and it gets better with activity. It is worse in the morning (after sleeping and not moving). The muscle insertion hurts very focally as it joins into the bone, but there is little to no pain at all with passive motion. There are some cases of isolated, primary enthesitis which are very poorly studied and understood. It is known to be associated with other autoimmune diseases, like spondyloarthropathies and psoriasis (thought to often precede psoriatic arthritis). A common autoimmune enthesitis is at the heel, where the Achilles tendon attaches to the calcaneus.

Enthesitis
Typical joint showing the entheses
SpecialtyRheumatology


It is associated with HLA B27 arthropathies, such as ankylosing spondylitis, psoriatic arthritis, and reactive arthritis.[3][4] Symptoms include multiple points of tenderness at the heel, tibial tuberosity, iliac crest, and other tendon insertion sites.

Images edit

 
Sagittal magnetic resonance images of ankle region: psoriatic arthritis. (a) Short tau inversion recovery (STIR) image, showing high signal intensity at the Achilles tendon insertion (enthesitis, thick arrow) and in the synovium of the ankle joint (synovitis, long thin arrow). Bone marrow oedema is seen at the tendon insertion (short thin arrow). (b, c) T1 weighted images of a different section of the same patient, before (panel b) and after (panel c) intravenous contrast injection, confirm inflammation (large arrow) at the enthesis and reveal bone erosion at tendon insertion (short thin arrows).

Related conditions edit

Anatomically close but separate conditions are:

  • Apophysitis, inflammation of the bony attachment, generally associated with overuse among growing children.[5][6][7]
  • Tendinopathy is a disorder of the tendon, and is associated with direct injury or repetitive activities.[8]

See also edit

References edit

  1. ^ Maria Antonietta D'Agostino, MD; Ignazio Olivieri, MD (June 2006). "Enthesitis". Best Practice & Research Clinical Rheumatology. Clinical Rheumatology. 20 (3): 473–86. doi:10.1016/j.berh.2006.03.007. PMID 16777577.
  2. ^ The Free Dictionary (2009). "Enthesitis". Retrieved 2010-11-27.
  3. ^ Schett, G; Lories, RJ; D'Agostino, MA; Elewaut, D; Kirkham, B; Soriano, ER; McGonagle, D (November 2017). "Enthesitis: from pathophysiology to treatment". Nature Reviews Rheumatology (Review). 13 (12): 731–41. doi:10.1038/nrrheum.2017.188. PMID 29158573.
  4. ^ Schmitt, SK (June 2017). "Reactive Arthritis". Infectious Disease Clinics of North America (Review). 31 (2): 265–77. doi:10.1016/j.idc.2017.01.002. PMID 28292540.
  5. ^ "OrthoKids - Osgood-Schlatter's Disease".
  6. ^ "Sever's Disease". Kidshealth.org. Retrieved 2014-04-29.
  7. ^ Hendrix CL (2005). "Calcaneal apophysitis (Sever disease)". Clinics in Podiatric Medicine and Surgery. 22 (1): 55–62, vi. doi:10.1016/j.cpm.2004.08.011. PMID 15555843.
  8. ^ "Tendinitis". National Institute of Arthritis and Musculoskeletal and Skin Diseases. 12 April 2017. Retrieved 18 November 2018.

External links edit

enthesitis, inflammation, entheses, sites, where, tendons, ligaments, insert, into, bone, enthesopathy, pathologic, condition, entheses, early, clinical, manifestations, aching, sensation, akin, working, much, gets, better, with, activity, worse, morning, afte. Enthesitis is inflammation of the entheses the sites where tendons or ligaments insert into the bone 1 2 It is an enthesopathy a pathologic condition of the entheses Early clinical manifestations are an aching sensation akin to working out too much and it gets better with activity It is worse in the morning after sleeping and not moving The muscle insertion hurts very focally as it joins into the bone but there is little to no pain at all with passive motion There are some cases of isolated primary enthesitis which are very poorly studied and understood It is known to be associated with other autoimmune diseases like spondyloarthropathies and psoriasis thought to often precede psoriatic arthritis A common autoimmune enthesitis is at the heel where the Achilles tendon attaches to the calcaneus EnthesitisTypical joint showing the enthesesSpecialtyRheumatologyThis section needs additional citations for verification Please help improve this article by adding citations to reliable sources in this section Unsourced material may be challenged and removed October 2019 Learn how and when to remove this template message It is associated with HLA B27 arthropathies such as ankylosing spondylitis psoriatic arthritis and reactive arthritis 3 4 Symptoms include multiple points of tenderness at the heel tibial tuberosity iliac crest and other tendon insertion sites Contents 1 Images 2 Related conditions 3 See also 4 References 5 External linksImages edit nbsp Sagittal magnetic resonance images of ankle region psoriatic arthritis a Short tau inversion recovery STIR image showing high signal intensity at the Achilles tendon insertion enthesitis thick arrow and in the synovium of the ankle joint synovitis long thin arrow Bone marrow oedema is seen at the tendon insertion short thin arrow b c T1 weighted images of a different section of the same patient before panel b and after panel c intravenous contrast injection confirm inflammation large arrow at the enthesis and reveal bone erosion at tendon insertion short thin arrows Related conditions editAnatomically close but separate conditions are Apophysitis inflammation of the bony attachment generally associated with overuse among growing children 5 6 7 Tendinopathy is a disorder of the tendon and is associated with direct injury or repetitive activities 8 See also editEnthesis plural Entheses References edit Maria Antonietta D Agostino MD Ignazio Olivieri MD June 2006 Enthesitis Best Practice amp Research Clinical Rheumatology Clinical Rheumatology 20 3 473 86 doi 10 1016 j berh 2006 03 007 PMID 16777577 The Free Dictionary 2009 Enthesitis Retrieved 2010 11 27 Schett G Lories RJ D Agostino MA Elewaut D Kirkham B Soriano ER McGonagle D November 2017 Enthesitis from pathophysiology to treatment Nature Reviews Rheumatology Review 13 12 731 41 doi 10 1038 nrrheum 2017 188 PMID 29158573 Schmitt SK June 2017 Reactive Arthritis Infectious Disease Clinics of North America Review 31 2 265 77 doi 10 1016 j idc 2017 01 002 PMID 28292540 OrthoKids Osgood Schlatter s Disease Sever s Disease Kidshealth org Retrieved 2014 04 29 Hendrix CL 2005 Calcaneal apophysitis Sever disease Clinics in Podiatric Medicine and Surgery 22 1 55 62 vi doi 10 1016 j cpm 2004 08 011 PMID 15555843 Tendinitis National Institute of Arthritis and Musculoskeletal and Skin Diseases 12 April 2017 Retrieved 18 November 2018 External links edit Retrieved from https en wikipedia org w index php title Enthesitis amp oldid 1182763706, wikipedia, wiki, book, books, library,

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