^ abcGRCh38: Ensembl release 89: ENSG00000143924 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000032624 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Entrez Gene: EML4 echinoderm microtubule associated protein like 4".
^Choi YL, Takeuchi K, Soda M, Inamura K, Togashi Y, Hatano S, Enomoto M, Hamada T, Haruta H, Watanabe H, Kurashina K, Hatanaka H, Ueno T, Takada S, Yamashita Y, Sugiyama Y, Ishikawa Y, Mano H (July 2008). "Identification of novel isoforms of the EML4-ALK transforming gene in non-small cell lung cancer". Cancer Res. 68 (13): 4971–6. doi:10.1158/0008-5472.CAN-07-6158. PMID 18593892.
Further readingedit
Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Heidebrecht HJ, Buck F, Pollmann M, et al. (2000). "Cloning and localization of C2orf2(ropp120), a previously unknown WD repeat protein". Genomics. 68 (3): 348–50. doi:10.1006/geno.2000.6301. PMID 10995578.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC514446. PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC528928. PMID 15489334.
Rush J, Moritz A, Lee KA, et al. (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nat. Biotechnol. 23 (1): 94–101. doi:10.1038/nbt1046. PMID 15592455. S2CID 7200157.
Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. Bibcode:2005Natur.434..724H. doi:10.1038/nature03466. PMID 15815621.
Pollmann M, Parwaresch R, Adam-Klages S, et al. (2006). "Human EML4, a novel member of the EMAP family, is essential for microtubule formation". Exp. Cell Res. 312 (17): 3241–51. doi:10.1016/j.yexcr.2006.06.035. PMID 16890222.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC1847948. PMID 17353931.
External linksedit
Overview of all the structural information available in the PDB for UniProt: Q9HC35 (Human Echinoderm microtubule-associated protein-like 4 (EML4)) at the PDBe-KB.
This article on a gene on human chromosome 2 is a stub. You can help Wikipedia by expanding it.
eml4, echinoderm, microtubule, associated, protein, like, protein, that, humans, encoded, gene, available, structurespdbortholog, search, pdbe, rcsblist, codes4cgcidentifiersaliases, c2orf2, elp120, emap, emapl4, ropp120, echinoderm, microtubule, associated, p. Echinoderm microtubule associated protein like 4 is a protein that in humans is encoded by the EML4 gene 5 EML4Available structuresPDBOrtholog search PDBe RCSBList of PDB id codes4CGCIdentifiersAliasesEML4 C2orf2 ELP120 EMAP 4 EMAPL4 ROPP120 echinoderm microtubule associated protein like 4 EMAP like 4External IDsOMIM 607442 MGI 1926048 HomoloGene 56841 GeneCards EML4Gene location Human Chr Chromosome 2 human 1 Band2p21Start42 169 353 bp 1 End42 332 548 bp 1 Gene location Mouse Chr Chromosome 17 mouse 2 Band17 17 E4Start83 658 360 bp 2 End83 787 790 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed intibiajejunal mucosavisceral pleurathymusduodenumrectumpylorusspleenparotid glandlymph nodeTop expressed inhandmaxillary prominencemolarprimitive streakabdominal wallsecondary oocyterenal corpusclemedullary collecting ductciliary bodyotolith organMore reference expression dataBioGPSMore reference expression dataGene ontologyMolecular functionmicrotubule binding molecular functionCellular componentcytoplasm microtubule cytoskeleton membrane microtubule cytoskeleton mitotic spindleBiological processmicrotubule based process mitotic cell cycle microtubule cytoskeleton organizationSources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez2743678798EnsemblENSG00000143924ENSMUSG00000032624UniProtQ9HC35Q3UMY5RefSeq mRNA NM 001145076NM 019063NM 001114361NM 001114362NM 001286567NM 199466NM 001357886NM 001379373NM 001379374RefSeq protein NP 001138548NP 061936NP 001107833NP 001107834NP 001273496NP 955760NP 001344815NP 001366302NP 001366303Location UCSC Chr 2 42 17 42 33 MbChr 17 83 66 83 79 MbPubMed search 3 4 WikidataView Edit HumanView Edit Mouse This protein is involved in cancers when spliced with the anaplastic lymphoma kinase 6 References edit a b c GRCh38 Ensembl release 89 ENSG00000143924 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000032624 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Entrez Gene EML4 echinoderm microtubule associated protein like 4 Choi YL Takeuchi K Soda M Inamura K Togashi Y Hatano S Enomoto M Hamada T Haruta H Watanabe H Kurashina K Hatanaka H Ueno T Takada S Yamashita Y Sugiyama Y Ishikawa Y Mano H July 2008 Identification of novel isoforms of the EML4 ALK transforming gene in non small cell lung cancer Cancer Res 68 13 4971 6 doi 10 1158 0008 5472 CAN 07 6158 PMID 18593892 Further reading editAndersson B Wentland MA Ricafrente JY et al 1996 A double adaptor method for improved shotgun library construction Anal Biochem 236 1 107 13 doi 10 1006 abio 1996 0138 PMID 8619474 Yu W Andersson B Worley KC et al 1997 Large scale concatenation cDNA sequencing Genome Res 7 4 353 8 doi 10 1101 gr 7 4 353 PMC 139146 PMID 9110174 Heidebrecht HJ Buck F Pollmann M et al 2000 Cloning and localization of C2orf2 ropp120 a previously unknown WD repeat protein Genomics 68 3 348 50 doi 10 1006 geno 2000 6301 PMID 10995578 Strausberg RL Feingold EA Grouse LH et al 2003 Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 99 26 16899 903 Bibcode 2002PNAS 9916899M doi 10 1073 pnas 242603899 PMC 139241 PMID 12477932 Ota T Suzuki Y Nishikawa T et al 2004 Complete sequencing and characterization of 21 243 full length human cDNAs Nat Genet 36 1 40 5 doi 10 1038 ng1285 PMID 14702039 Beausoleil SA Jedrychowski M Schwartz D et al 2004 Large scale characterization of HeLa cell nuclear phosphoproteins Proc Natl Acad Sci U S A 101 33 12130 5 Bibcode 2004PNAS 10112130B doi 10 1073 pnas 0404720101 PMC 514446 PMID 15302935 Gerhard DS Wagner L Feingold EA et al 2004 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 10B 2121 7 doi 10 1101 gr 2596504 PMC 528928 PMID 15489334 Rush J Moritz A Lee KA et al 2005 Immunoaffinity profiling of tyrosine phosphorylation in cancer cells Nat Biotechnol 23 1 94 101 doi 10 1038 nbt1046 PMID 15592455 S2CID 7200157 Hillier LW Graves TA Fulton RS et al 2005 Generation and annotation of the DNA sequences of human chromosomes 2 and 4 Nature 434 7034 724 31 Bibcode 2005Natur 434 724H doi 10 1038 nature03466 PMID 15815621 Pollmann M Parwaresch R Adam Klages S et al 2006 Human EML4 a novel member of the EMAP family is essential for microtubule formation Exp Cell Res 312 17 3241 51 doi 10 1016 j yexcr 2006 06 035 PMID 16890222 Olsen JV Blagoev B Gnad F et al 2006 Global in vivo and site specific phosphorylation dynamics in signaling networks Cell 127 3 635 48 doi 10 1016 j cell 2006 09 026 PMID 17081983 S2CID 7827573 Ewing RM Chu P Elisma F et al 2007 Large scale mapping of human protein protein interactions by mass spectrometry Mol Syst Biol 3 1 89 doi 10 1038 msb4100134 PMC 1847948 PMID 17353931 External links editOverview of all the structural information available in the PDB for UniProt Q9HC35 Human Echinoderm microtubule associated protein like 4 EML4 at the PDBe KB nbsp This article on a gene on human chromosome 2 is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title EML4 amp oldid 1115521531, wikipedia, wiki, book, books, library,
