Thus, the two substrates of this enzyme are ATP and dephospho-CoA, whereas its two products are ADP and CoA.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:dephospho-CoA 3'-phosphotransferase. Other names in common use include dephosphocoenzyme A kinase (phosphorylating), 3'-dephospho-CoA kinase, and dephosphocoenzyme A kinase. This enzyme participates in pantothenate and coa biosynthesis.
Structural studiesedit
As of late 2007, 8 structures have been solved for this class of enzymes, with PDB accession codes 1JJV, 1N3B, 1T3H, 1VHL, 1VHT, 1VIY, 2GRJ, and 2IF2.
Referencesedit
Abiko Y (1970). "Pantothenic acid and coenzyme A:dephospho-CoA pyrophosphorylase and dephospho-CoA kinase as a possible bifunctional enzyme complex (ATP:pantetheine-4'-phosphate adenylyltransferase, EC 2.7.7.3 and ATP:dephospho-CoA-3'-phosphotransferase EC 2.7.1.24)". Methods Enzymol. 18A: 358–364. doi:10.1016/0076-6879(71)18327-9.
HOAGLAND MB, NOVELLI GD (1954). "Biosynthesis of coenzyme A from phospho-pantetheine and of pantetheine from pantothenate". J. Biol. Chem. 207 (2): 767–73. PMID 13163064.
Wang TP, Kaplan NO (1954). "Kinases for the synthesis of coenzyme A and triphosphopyridine nucleotide". J. Biol. Chem. 206 (1): 311–325. PMID 13130551.
dephospho, kinase, enzymology, dephospho, kinase, enzyme, that, catalyzes, chemical, reactiondephospho, kinaseidentifiersec, 24cas, 9026, 9databasesintenzintenz, viewbrendabrenda, entryexpasynicezyme, viewkeggkegg, entrymetacycmetabolic, pathwaypriamprofilepdb. In enzymology a dephospho CoA kinase EC 2 7 1 24 is an enzyme that catalyzes the chemical reactiondephospho CoA kinaseIdentifiersEC no 2 7 1 24CAS no 9026 83 9DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumGene OntologyAmiGO QuickGOSearchPMCarticlesPubMedarticlesNCBIproteins ATP dephospho CoA displaystyle rightleftharpoons ADP CoAThus the two substrates of this enzyme are ATP and dephospho CoA whereas its two products are ADP and CoA This enzyme belongs to the family of transferases specifically those transferring phosphorus containing groups phosphotransferases with an alcohol group as acceptor The systematic name of this enzyme class is ATP dephospho CoA 3 phosphotransferase Other names in common use include dephosphocoenzyme A kinase phosphorylating 3 dephospho CoA kinase and dephosphocoenzyme A kinase This enzyme participates in pantothenate and coa biosynthesis Structural studies editAs of late 2007 8 structures have been solved for this class of enzymes with PDB accession codes 1JJV 1N3B 1T3H 1VHL 1VHT 1VIY 2GRJ and 2IF2 References editAbiko Y 1970 Pantothenic acid and coenzyme A dephospho CoA pyrophosphorylase and dephospho CoA kinase as a possible bifunctional enzyme complex ATP pantetheine 4 phosphate adenylyltransferase EC 2 7 7 3 and ATP dephospho CoA 3 phosphotransferase EC 2 7 1 24 Methods Enzymol 18A 358 364 doi 10 1016 0076 6879 71 18327 9 HOAGLAND MB NOVELLI GD 1954 Biosynthesis of coenzyme A from phospho pantetheine and of pantetheine from pantothenate J Biol Chem 207 2 767 73 PMID 13163064 Wang TP Kaplan NO 1954 Kinases for the synthesis of coenzyme A and triphosphopyridine nucleotide J Biol Chem 206 1 311 325 PMID 13130551 Portal nbsp Biology This EC 2 7 enzyme related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Dephospho CoA kinase amp oldid 1172344459, wikipedia, wiki, book, books, library,
