This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is dCTP aminohydrolase. Other names in common use include deoxycytidine triphosphate deaminase, and 5-methyl-dCTP deaminase. This enzyme participates in pyrimidine metabolism.
Structural studiesedit
As of late 2007, 9 structures have been solved for this class of enzymes, with PDB accession codes 1OGH, 1PKH, 1PKJ, 1PKK, 1XS1, 1XS4, 1XS6, 2J4H, and 2J4Q.
Referencesedit
Tomita F, Takahashi I (1969). "A novel enzyme, dCTP deaminase, found in Bacillus subtilis infected with phage PBS I". Biochim. Biophys. Acta. 179 (1): 18–27. doi:10.1016/0005-2787(69)90117-8. PMID 4976547.
dctp, deaminase, enzymology, enzyme, that, catalyzes, chemical, reactionidentifiersec, 13cas, 37289, 2databasesintenzintenz, viewbrendabrenda, entryexpasynicezyme, viewkeggkegg, entrymetacycmetabolic, pathwaypriamprofilepdb, structuresrcsb, pdbe, pdbsumgene, o. In enzymology a dCTP deaminase EC 3 5 4 13 is an enzyme that catalyzes the chemical reactiondCTP deaminaseIdentifiersEC no 3 5 4 13CAS no 37289 18 2DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumGene OntologyAmiGO QuickGOSearchPMCarticlesPubMedarticlesNCBIproteins dCTP H2O displaystyle rightleftharpoons dUTP NH3 Thus the two substrates of this enzyme are dCTP and H2O whereas its two products are dUTP and NH3 This enzyme belongs to the family of hydrolases those acting on carbon nitrogen bonds other than peptide bonds specifically in cyclic amidines The systematic name of this enzyme class is dCTP aminohydrolase Other names in common use include deoxycytidine triphosphate deaminase and 5 methyl dCTP deaminase This enzyme participates in pyrimidine metabolism Structural studies editAs of late 2007 9 structures have been solved for this class of enzymes with PDB accession codes 1OGH 1PKH 1PKJ 1PKK 1XS1 1XS4 1XS6 2J4H and 2J4Q References editTomita F Takahashi I 1969 A novel enzyme dCTP deaminase found in Bacillus subtilis infected with phage PBS I Biochim Biophys Acta 179 1 18 27 doi 10 1016 0005 2787 69 90117 8 PMID 4976547 Portal nbsp Biology This EC 3 5 enzyme related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title DCTP deaminase amp oldid 1172344075, wikipedia, wiki, book, books, library,
