D-alanine gamma-glutamyltransferase

In enzymology, a D-alanine gamma-glutamyltransferase (EC 2.3.2.14) is an enzyme that catalyzes the chemical reaction

D-alanine gamma-glutamyltransferase
Identifiers
EC no.	2.3.2.14
CAS no.	9046-27-9
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

L-glutamine + D-alanine ${\displaystyle \rightleftharpoons }$ NH₃ + gamma-L-glutamyl-D-alanine

Thus, the two substrates of this enzyme are L-glutamine and D-alanine, whereas its two products are NH₃ and gamma-L-glutamyl-D-alanine.

This enzyme belongs to the family of transferases, specifically the aminoacyltransferases. The systematic name of this enzyme class is L-glutamine:D-alanine gamma-glutamyltransferase.

References

• Kawasaki Y, Ogawa T, Sasaoka K (1982). "Occurrence and some properties of a novel gamma-glutamyltransferase responsible for the synthesis of gamma-L-glutamyl-D-alanine in pea-seedlings". Biochim. Biophys. Acta. 716: 194–200. doi:10.1016/0304-4165(82)90268-9.