Wikipedia
Cyclohexanol dehydrogenase
In enzymology, a cyclohexanol dehydrogenase (EC 1.1.1.245) is an enzyme that catalyzes the chemical reaction
| cyclohexanol dehydrogenase | |
|---|---|
| Identifiers | |
| EC no. | 1.1.1.245 |
| CAS no. | 63951-98-4 |
| Databases | |
| IntEnz | IntEnz view |
| BRENDA | BRENDA entry |
| ExPASy | NiceZyme view |
| KEGG | KEGG entry |
| MetaCyc | metabolic pathway |
| PRIAM | profile |
| PDB structures | RCSB PDB PDBe PDBsum |
| Gene Ontology | AmiGO / QuickGO |
- cyclohexanol + NAD+ cyclohexanone + NADH + H+
Thus, the two substrates of this enzyme are cyclohexanol and NAD+, whereas its 3 products are cyclohexanone, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cyclohexanol:NAD+ oxidoreductase. This enzyme participates in caprolactam degradation.
References edit
- Dangel W, Tschech A, Fuchs G (1989). "Enzyme-reactions involved in anaerobic cyclohexanol metabolism by a denitrifying Pseudomonas species". Arch. Microbiol. 152 (3): 273–279. doi:10.1007/BF00409663. PMID 2505723.
- Donoghue NA, Trudgill PW (1975). "The metabolism of cyclohexanol by Acinetobacter NCIB 9871". Eur. J. Biochem. 60 (1): 1–7. doi:10.1111/j.1432-1033.1975.tb20968.x. PMID 1261.
- Trower MK, Buckland RM, Higgins R, Griffin M (1985). "Isolation and Characterization of a Cyclohexane-Metabolizing Xanthobacter sp". Appl. Environ. Microbiol. 49 (5): 1282–1289. PMC 238543. PMID 16346796.