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Condensation reaction

In organic chemistry, a condensation reaction is a type of chemical reaction in which two molecules are combined to form a single molecule, usually with the loss of a small molecule such as water.[1] If water is lost, the reaction is also known as a dehydration synthesis. However other molecules can also be lost, such as ammonia, ethanol, acetic acid and hydrogen sulfide.[2]

The addition of the two molecules typically proceeds in a step-wise fashion to the addition product, usually in equilibrium, and with loss of a water molecule (hence the name condensation).[3] The reaction may otherwise involve the functional groups of the molecule, and is a versatile class of reactions that can occur in acidic or basic conditions or in the presence of a catalyst. This class of reactions is a vital part of life as it is essential to the formation of peptide bonds between amino acids and to the biosynthesis of fatty acids.[4]

Idealized scheme showing condensation of two amino acids to give a peptide bond.

Many variations of condensation reactions exist. Common examples include the aldol condensation and the Knoevenagel condensation, which both form water as a by-product, as well as the Claisen condensation and the Dieckman condensation (intramolecular Claisen condensation), which form alcohols as by-products.[5]

See also edit

References edit

  1. ^ "25.18 Condensation Reactions". Book: Introductory Chemistry (CK-12). Chemistry Libre Texts. 12 August 2020. Retrieved 9 January 2021.
  2. ^ "Condensation Reaction". IUPAC Compendium of Chemical Terminology (Gold Book). IUPAC. 2014. doi:10.1351/goldbook.C01238. Retrieved 7 December 2017.
  3. ^ Fakirov, S. (2019-02-01). "Condensation Polymers: Their Chemical Peculiarities Offer Great Opportunities". Progress in Polymer Science. 89: 1–18. doi:10.1016/j.progpolymsci.2018.09.003. ISSN 0079-6700. S2CID 105101288.
  4. ^ Voet, Donald; Voet, Judith; Pratt, Chriss (2008). Fundamentals of Biochemistry. Hoboken, NJ: John Wiley & Sons, Inc. pp. 88. ISBN 978-0470-12930-2.
  5. ^ Bruckner, Reinhard (2002). Advanced Organic Chemistry (First ed.). San Diego, California: Harcourt Academic Press. pp. 414–427. ISBN 0-12-138110-2.

condensation, reaction, organic, chemistry, condensation, reaction, type, chemical, reaction, which, molecules, combined, form, single, molecule, usually, with, loss, small, molecule, such, water, water, lost, reaction, also, known, dehydration, synthesis, how. In organic chemistry a condensation reaction is a type of chemical reaction in which two molecules are combined to form a single molecule usually with the loss of a small molecule such as water 1 If water is lost the reaction is also known as a dehydration synthesis However other molecules can also be lost such as ammonia ethanol acetic acid and hydrogen sulfide 2 The addition of the two molecules typically proceeds in a step wise fashion to the addition product usually in equilibrium and with loss of a water molecule hence the name condensation 3 The reaction may otherwise involve the functional groups of the molecule and is a versatile class of reactions that can occur in acidic or basic conditions or in the presence of a catalyst This class of reactions is a vital part of life as it is essential to the formation of peptide bonds between amino acids and to the biosynthesis of fatty acids 4 Idealized scheme showing condensation of two amino acids to give a peptide bond Many variations of condensation reactions exist Common examples include the aldol condensation and the Knoevenagel condensation which both form water as a by product as well as the Claisen condensation and the Dieckman condensation intramolecular Claisen condensation which form alcohols as by products 5 See also editAnabolism Hydrolysis the opposite of a condensation reaction Condensed tanninsReferences edit 25 18 Condensation Reactions Book Introductory Chemistry CK 12 Chemistry Libre Texts 12 August 2020 Retrieved 9 January 2021 Condensation Reaction IUPAC Compendium of Chemical Terminology Gold Book IUPAC 2014 doi 10 1351 goldbook C01238 Retrieved 7 December 2017 Fakirov S 2019 02 01 Condensation Polymers Their Chemical Peculiarities Offer Great Opportunities Progress in Polymer Science 89 1 18 doi 10 1016 j progpolymsci 2018 09 003 ISSN 0079 6700 S2CID 105101288 Voet Donald Voet Judith Pratt Chriss 2008 Fundamentals of Biochemistry Hoboken NJ John Wiley amp Sons Inc pp 88 ISBN 978 0470 12930 2 Bruckner Reinhard 2002 Advanced Organic Chemistry First ed San Diego California Harcourt Academic Press pp 414 427 ISBN 0 12 138110 2 Retrieved from https en wikipedia org w index php title Condensation reaction amp oldid 1136424691, wikipedia, wiki, book, books, library,

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