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Collecting duct carcinoma

Collecting duct carcinoma (CDC) is a type of kidney cancer that originates in the papillary duct of the kidney. It is rare, accounting for 1-3% of all kidney cancers.[2] It is also recently described; a 2002 review found just 40 case reports worldwide.[3] Previously, due to its location, CDC was commonly diagnosed as renal cell carcinoma or a subtype of renal cell carcinoma.[4] However, CDC does not respond well to chemotherapy drugs used for renal cell carcinoma, and progresses and spreads more quickly.

Collecting duct carcinoma
Other namesBellini duct carcinoma[1]
Collecting duct carcinoma. H&E stain.
SpecialtyOncology/nephrology
Collecting duct carcinoma in computed tomography

Signs and symptoms edit

Signs and symptoms are as for kidney cancer.[citation needed]

Histology edit

Histologic examination of collecting duct carcinoma demonstrates an infiltrative lesion with tubulopapillary, irregular channels lined by high grade hobnail cells with marked desmoplastic response and brisk neutrophilic infiltrate.[citation needed]

Treatment edit

History edit

CDC was thought to be renal cell carcinoma, until "recently developed techniques of lectin histochemistry" helped forward knowledge of kidney duct cancers.[5]

References edit

  1. ^ Amin MB, MacLennan GT, Gupta R, Grignon D, Paraf F, Vieillefond A, Paner GP, Stovsky M, Young AN, Srigley JR, Cheville JC (March 2009). "Tubulocystic carcinoma of the kidney: clinicopathologic analysis of 31 cases of a distinctive rare subtype of renal cell carcinoma". Am. J. Surg. Pathol. 33 (3): 384–92. doi:10.1097/PAS.0b013e3181872d3f. PMID 19011562.
  2. ^ Fakhrai N, Haitel A, Balassy C, Zielinski CC, Schmidinger M (January 2005). "Major response and clinical benefit following third-line treatment for Bellini duct carcinoma". Wien. Klin. Wochenschr. 117 (1–2): 63–5. doi:10.1007/s00508-004-0289-4. PMID 15986594.
  3. ^ Singh I, Nabi G (2002). "Bellini duct carcinoma: review of diagnosis and management" (PDF). Int Urol Nephrol. 34 (1): 91–5. doi:10.1023/A:1021315130481. PMID 12549647.
  4. ^ Méjean A, Rouprêt M, Larousserie F, Hopirtean V, Thiounn N, Dufour B (April 2003). "Is there a place for radical nephrectomy in the presence of metastatic collecting duct (Bellini) carcinoma?". J. Urol. 169 (4): 1287–90. doi:10.1097/01.ju.0000050221.51509.f5. PMID 12629344.
  5. ^ O Natsume; S Ozono; T Futami & M Ohta (1997). "Bellini duct carcinoma: a case report". Japanese Journal of Clinical Oncology. 27 (2): 107–110. doi:10.1093/jjco/27.2.107. PMID 9152800.

External links edit

collecting, duct, carcinoma, type, kidney, cancer, that, originates, papillary, duct, kidney, rare, accounting, kidney, cancers, also, recently, described, 2002, review, found, just, case, reports, worldwide, previously, location, commonly, diagnosed, renal, c. Collecting duct carcinoma CDC is a type of kidney cancer that originates in the papillary duct of the kidney It is rare accounting for 1 3 of all kidney cancers 2 It is also recently described a 2002 review found just 40 case reports worldwide 3 Previously due to its location CDC was commonly diagnosed as renal cell carcinoma or a subtype of renal cell carcinoma 4 However CDC does not respond well to chemotherapy drugs used for renal cell carcinoma and progresses and spreads more quickly Collecting duct carcinomaOther namesBellini duct carcinoma 1 Collecting duct carcinoma H amp E stain SpecialtyOncology nephrology Collecting duct carcinoma in computed tomography Contents 1 Signs and symptoms 2 Histology 3 Treatment 4 History 5 References 6 External linksSigns and symptoms editSigns and symptoms are as for kidney cancer citation needed Histology editHistologic examination of collecting duct carcinoma demonstrates an infiltrative lesion with tubulopapillary irregular channels lined by high grade hobnail cells with marked desmoplastic response and brisk neutrophilic infiltrate citation needed Treatment editThis section is empty You can help by adding to it February 2018 History editCDC was thought to be renal cell carcinoma until recently developed techniques of lectin histochemistry helped forward knowledge of kidney duct cancers 5 References edit Amin MB MacLennan GT Gupta R Grignon D Paraf F Vieillefond A Paner GP Stovsky M Young AN Srigley JR Cheville JC March 2009 Tubulocystic carcinoma of the kidney clinicopathologic analysis of 31 cases of a distinctive rare subtype of renal cell carcinoma Am J Surg Pathol 33 3 384 92 doi 10 1097 PAS 0b013e3181872d3f PMID 19011562 Fakhrai N Haitel A Balassy C Zielinski CC Schmidinger M January 2005 Major response and clinical benefit following third line treatment for Bellini duct carcinoma Wien Klin Wochenschr 117 1 2 63 5 doi 10 1007 s00508 004 0289 4 PMID 15986594 Singh I Nabi G 2002 Bellini duct carcinoma review of diagnosis and management PDF Int Urol Nephrol 34 1 91 5 doi 10 1023 A 1021315130481 PMID 12549647 Mejean A Roupret M Larousserie F Hopirtean V Thiounn N Dufour B April 2003 Is there a place for radical nephrectomy in the presence of metastatic collecting duct Bellini carcinoma J Urol 169 4 1287 90 doi 10 1097 01 ju 0000050221 51509 f5 PMID 12629344 O Natsume S Ozono T Futami amp M Ohta 1997 Bellini duct carcinoma a case report Japanese Journal of Clinical Oncology 27 2 107 110 doi 10 1093 jjco 27 2 107 PMID 9152800 External links edit Retrieved from https en wikipedia org w index php title Collecting duct carcinoma amp oldid 1170972201, wikipedia, wiki, book, books, library,

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