Cloroqualone is a quinazolinone-class GABAergic and is an analogue of methaqualone developed in the 1980s and marketed mainly in France and some other European countries. It has sedative and antitussive properties resulting from its agonist activity at the β subtype of the GABAa receptor and sigma-1 receptor, and was sold either alone or in combination with other ingredients as a cough medicine. Cloroqualone has weaker sedative properties than methaqualone and was sold for its useful cough-suppressing effects, but was withdrawn from the French market in 1994 because of concerns about its potential for abuse and overdose.[1]
cloroqualone, quinazolinone, class, gabaergic, analogue, methaqualone, developed, 1980s, marketed, mainly, france, some, other, european, countries, sedative, antitussive, properties, resulting, from, agonist, activity, subtype, gabaa, receptor, sigma, recepto. Cloroqualone is a quinazolinone class GABAergic and is an analogue of methaqualone developed in the 1980s and marketed mainly in France and some other European countries It has sedative and antitussive properties resulting from its agonist activity at the b subtype of the GABAa receptor and sigma 1 receptor and was sold either alone or in combination with other ingredients as a cough medicine Cloroqualone has weaker sedative properties than methaqualone and was sold for its useful cough suppressing effects but was withdrawn from the French market in 1994 because of concerns about its potential for abuse and overdose 1 CloroqualoneClinical dataPregnancycategory Routes ofadministration ATC codenonePharmacokinetic dataBioavailability Metabolism Elimination half life Excretion IdentifiersIUPAC name 3 2 6 Dichlorophenyl 2 ethyl 4 quinazolinoneCAS Number25509 07 3 NPubChem CID63338DrugBank NChemSpider57005 YUNII172D4Q6LOWChEMBLChEMBL2106114 NCompTox Dashboard EPA DTXSID10180201ECHA InfoCard100 042 761Chemical and physical dataFormulaC 16H 12Cl 2N 2OMolar mass319 185 g mol 13D model JSmol Interactive imageSMILES Clc3cccc Cl c3N 1C O c2c N C 1CC cccc2InChI InChI 1S C16H12Cl2N2O c1 2 14 19 13 9 4 3 6 10 13 16 21 20 14 15 11 17 7 5 8 12 15 18 h3 9H 2H2 1H3 YKey SONHVLIDLXLSOL UHFFFAOYSA N Y N Y what is this verify See also editMethaqualone Afloqualone Etaqualone Methylmethaqualone Mecloqualone Mebroqualone Diproqualone Gamma Aminobutyric acidReferences edit Cloroqualone PubChem U S National Library of Medicine Retrieved 2022 07 29 nbsp This sedative related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Cloroqualone amp oldid 1143242757, wikipedia, wiki, book, books, library,
